Study on the tongue manifestations for the blood-stasis and toxin syndrome in the stable patients of coronary heart disease

Yan Feng; Hao Xu; Dan Qu; Feng Zheng; Da-zhuo Shi; Ke-ji Chen

doi:10.1007/s11655-011-0615-4

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Study on the tongue manifestations for the blood-stasis and toxin syndrome in the stable patients of coronary heart disease

Updated：2021-08-27

- Study on the tongue manifestations for the blood-stasis and toxin syndrome in the stable patients of coronary heart disease
- Chinese Journal of Integrative Medicine Vol. 17, Issue 5, Pages: 333-338(2011)
- Affiliations：
  
  1. Graduate School of China Academy of Chinese Medical Sciences,Beijing,China
  2. National Integrative Medicine Center for Cardiovascular Disease, China-Japan Friendship Hospital,Beijing,China
  3. Beijing University of Chinese Medicine,Beijing,China
  4. Xiyuan Hospital, China Academy of Chinese Medical Sciences,Beijing,China
- Author bio：
- Funds：
  
  Supported by National Major Project for Fundamental Research and Development (No. 2006CB504803);National Natural Science Foundation of China (No. 30973702);Beijing Project of Science and Technology Plan (No. D08050703020801);Major Discipline Project of China-Japan Friendship Hospital
- DOI：10.1007/s11655-011-0615-4
  CLC：
- Published：2011，
  
  Published Online：25 May 2011，
Scan for full text
Feng, Y., Xu, H., Qu, D. et al. Study on the tongue manifestations for the blood-stasis and toxin syndrome in the stable patients of coronary heart disease., Chin. J. Integr. Med. 17, 333–338 (2011). https://doi.org/10.1007/s11655-011-0615-4

Yan Feng, Hao Xu, Dan Qu, et al. Study on the tongue manifestations for the blood-stasis and toxin syndrome in the stable patients of coronary heart disease. [J]. Chinese Journal of Integrative Medicine 17(5):333-338(2011)
Feng, Y., Xu, H., Qu, D. et al. Study on the tongue manifestations for the blood-stasis and toxin syndrome in the stable patients of coronary heart disease., Chin. J. Integr. Med. 17, 333–338 (2011). https://doi.org/10.1007/s11655-011-0615-4 DOI：

Yan Feng, Hao Xu, Dan Qu, et al. Study on the tongue manifestations for the blood-stasis and toxin syndrome in the stable patients of coronary heart disease. [J]. Chinese Journal of Integrative Medicine 17(5):333-338(2011) DOI： 10.1007/s11655-011-0615-4.

摘要

To explore the tongue manifestations for the blood-stasis and toxin syndrome in the stable patients of coronary heart disease (CHD) according to the acute cardiovascular events (ACEs) in one-year follow-up which based on the pathogenesis hypothesis of “blood-stasis and toxin causing catastrophe”. Totally 254 stable CHD cases were enrolled after diagnosed by coronary angiography

their tongue appearances were recorded by the digital camera of uniform type

29 cases with ACEs during one-year follow-up were assigned in ACEs group. The non-ACEs were matched in proportion of 2:1 according to the gender

age (±2.5 years)

diabetes mellitus history and previous acute coronary syndrome hospitalization history in the non-ACEs group

and 54 cases were eligibly included. The differences of tongue appearance between the ACEs and non-ACEs group were compared. Fifteen cases manifested with bluish tongue (including bluish-grounding or bluish purple tongue)

among which 11 cases (37.9%) in the ACEs group and four cases (7.4%) in the non-ACEs group

and there was significant difference (P<0.002). Twenty six cases showed yellow tongue coating in the non-ACEs group

which was significantly higher than that in the ACEs group (48.1 vs. 10.3%

P=0.001). The tongue of sticky greasy coating was more frequently occurred in the non-ACEs group than that in the ACEs group (66.7% vs. 41.4%

P=0.026). The proportion of purplish-red sublingual vessel was higher in the ACEs group than that in the non-ACEs group (41.4% vs. 20.4%

P=0.041). Odd ratio (OR) analysis showed that the patients with bluish tongue

purplish-red sublingual vessel

dry-greasy or dirty greasy coating were more likely to experience ACEs during oneoneyear follow-up (OR: 11.67

95%CI: 3.34 year 3.34–40.81

P<0.001; OR: 2.76

95%CI: 1.02 1.02–7.44

P<0.05; OR: 3.12

95%

CI: 0.89 0.89–10.92

P=0.066). The bluish tongue (including bluish-grounding or bluish purple tongue) and purplish-red sublingual vessel were potential tongue manifestations of blood-stasis and toxin. The tongue coating changing from sticky greasy to dry greasy or dirty greasy was also probably a tongue manifestation of “transforming toxin”

which need demonstration by further study.

Abstract

their tongue appearances were recorded by the digital camera of uniform type

29 cases with ACEs during one-year follow-up were assigned in ACEs group. The non-ACEs were matched in proportion of 2:1 according to the gender

age (±2.5 years)

diabetes mellitus history and previous acute coronary syndrome hospitalization history in the non-ACEs group

among which 11 cases (37.9%) in the ACEs group and four cases (7.4%) in the non-ACEs group

and there was significant difference (P<0.002). Twenty six cases showed yellow tongue coating in the non-ACEs group

which was significantly higher than that in the ACEs group (48.1 vs. 10.3%

P=0.001). The tongue of sticky greasy coating was more frequently occurred in the non-ACEs group than that in the ACEs group (66.7% vs. 41.4%

P=0.026). The proportion of purplish-red sublingual vessel was higher in the ACEs group than that in the non-ACEs group (41.4% vs. 20.4%

P=0.041). Odd ratio (OR) analysis showed that the patients with bluish tongue

purplish-red sublingual vessel

dry-greasy or dirty greasy coating were more likely to experience ACEs during oneoneyear follow-up (OR: 11.67

95%CI: 3.34 year 3.34–40.81

P<0.001; OR: 2.76

95%CI: 1.02 1.02–7.44

P<0.05; OR: 3.12

95%

CI: 0.89 0.89–10.92

which need demonstration by further study.

关键词

coronary heart diseaseblood-stasis and toxintongue manifestations

Keywords

coronary heart diseaseblood-stasis and toxintongue manifestations

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Department of Cardiology, Guang’anmen Hospital, China Academy of Chinese Medical Sciences

Academy of Chinese Medical Sciences

Department of Cardiology, Guang’anmen Hospital

Department of Integrative Cardiology, China-Japan Friendship Hospital

Guangdong Provincial Hospital of Chinese Medicine

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