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Study on the complex prescription compatibility law of the cold and hot nature of Mahuang Decoction (麻黄汤) and its categorized formulae based on the cold-hot pad differentiating assay
- Chinese Journal of Integrative Medicine Vol. 17, Issue 4, Pages: 290-295(2011)
- Affiliations：
1. China Military Institute of Chinese Materia Medica,Beijing,China
2. Chengdu University of Traditional Chinese Medicine,Chengdu,China
3. Academy of Life Science and Technology, Kunming University of Science and Technology,Kunming,China
- Author bio：
- Funds：Supported by the Major State Basic Research Development Program of China (973 Program, No. 2007CB512607), the National Science Fund for Distinguished Young Scholars (No. 30625042), and National Science and Technology Major Project of the Ministry of Science and Technology of China (No. 2009ZX10005-017)
DOI：10.1007/s11655-011-0694-2
CLC：Published：2011，
Published Online：21 April 2011，
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Jia, L., Zhao, Yl., Wang, Jb. et al. Study on the complex prescription compatibility law of the cold and hot nature of Mahuang Decoction (麻黄汤) and its categorized formulae based on the cold-hot pad differentiating assay., Chin. J. Integr. Med. 17, 290–295 (2011). https://doi.org/10.1007/s11655-011-0694-2
Lei Jia, Yan-ling Zhao, Jia-bo Wang, et al. Study on the complex prescription compatibility law of the cold and hot nature of Mahuang Decoction (麻黄汤) and its categorized formulae based on the cold-hot pad differentiating assay. [J]. Chinese Journal of Integrative Medicine 17(4):290-295(2011)
Jia, L., Zhao, Yl., Wang, Jb. et al. Study on the complex prescription compatibility law of the cold and hot nature of Mahuang Decoction (麻黄汤) and its categorized formulae based on the cold-hot pad differentiating assay., Chin. J. Integr. Med. 17, 290–295 (2011). https://doi.org/10.1007/s11655-011-0694-2 DOI：
Lei Jia, Yan-ling Zhao, Jia-bo Wang, et al. Study on the complex prescription compatibility law of the cold and hot nature of Mahuang Decoction (麻黄汤) and its categorized formulae based on the cold-hot pad differentiating assay. [J]. Chinese Journal of Integrative Medicine 17(4):290-295(2011) DOI： 10.1007/s11655-011-0694-2.
摘要
To explore the complex prescription compatibility law of the cold and hot nature of Mahuang Decoction (麻黄汤
MHD) and Maxing Shigan Decoction (麻杏石甘汤
MXSGD)
both categorized both categorized MHD) and Maxing Shigan Decoction (both categorized MXSGD)
both categorized formulas but with different hot/cold natures. Oxygen consumption of mice was determined among three groups: MHD
MXSGD and the control; a cold-hot pad differentiating assay was used to observe the variability of temperature tropism among the groups of mice which was treated with MHD
MXSGD
and their compositions. Meanwhile
the total anti-oxidant capability (T-AOC) activity were detected. After administration of MHD
the mice showed increased oxygen consumption (P<0.01). Compared with MHD group
the remaining rate of MXSGD mice on the hot pad was found to be significantly increased with the cold-hot pad differentiating assay (P<0.05). There was no significant difference (P>0.05) among the remaining rates of MXSGD
MXSGD with high dose Gypsum Fibrosum (MXHGF) group
and MXSGD with low dose Gypsum Fibrosum (MXLGF) group mice. Compared with the MHD group
T-AOC activity of the mice in the Consensus Compositons group was significantly decreased (P=0.0494). Compared with the MXSGD group
T-AOC activity of Gypsum Fibrosum (GF) group was increased significantly (P=0.0013). The differences in cold and hot nature could be represented objectively between MHD with a hot nature and MXSGD with a cold nature. The reason may be the Gypsum Fibrosum which decreased the efficacy of the consensus compositions. However
increasing or decreasing the dose of Gypsum Fibrosum will not change the cold and hot nature of MXSGD.
Abstract
To explore the complex prescription compatibility law of the cold and hot nature of Mahuang Decoction (麻黄汤
MHD) and Maxing Shigan Decoction (麻杏石甘汤
MXSGD)
both categorized both categorized MHD) and Maxing Shigan Decoction (both categorized MXSGD)
both categorized formulas but with different hot/cold natures. Oxygen consumption of mice was determined among three groups: MHD
MXSGD and the control; a cold-hot pad differentiating assay was used to observe the variability of temperature tropism among the groups of mice which was treated with MHD
MXSGD
and their compositions. Meanwhile
the total anti-oxidant capability (T-AOC) activity were detected. After administration of MHD
the mice showed increased oxygen consumption (P<0.01). Compared with MHD group
the remaining rate of MXSGD mice on the hot pad was found to be significantly increased with the cold-hot pad differentiating assay (P<0.05). There was no significant difference (P>0.05) among the remaining rates of MXSGD
MXSGD with high dose Gypsum Fibrosum (MXHGF) group
and MXSGD with low dose Gypsum Fibrosum (MXLGF) group mice. Compared with the MHD group
T-AOC activity of the mice in the Consensus Compositons group was significantly decreased (P=0.0494). Compared with the MXSGD group
T-AOC activity of Gypsum Fibrosum (GF) group was increased significantly (P=0.0013). The differences in cold and hot nature could be represented objectively between MHD with a hot nature and MXSGD with a cold nature. The reason may be the Gypsum Fibrosum which decreased the efficacy of the consensus compositions. However
increasing or decreasing the dose of Gypsum Fibrosum will not change the cold and hot nature of MXSGD.
关键词
Mahuang Decoction and its categorized formulaecold and hot nature of Chinese drugscomplex prescription compatibility law of Chinese medicinecold-hot pad differentiating assay
Keywords
Mahuang Decoction and its categorized formulaecold and hot nature of Chinese drugscomplex prescription compatibility law of Chinese medicinecold-hot pad differentiating assay
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