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Effects and mechanisms of actions of Chinese herbal medicines for asthma
- Chinese Journal of Integrative Medicine Vol. 17, Issue 7, Pages: 483-491(2011)
- Affiliations：
1. Center for Chinese Medicine for Allergy and Asthma, Jaffe Food Allergy Institute, Pediatric Department, Division of Allergy and Immunology, The Mount Sinai School of Medicine,New York,USA
2. Respiratory Department, Zhangzhou Traditional Chinese Medicine Hospital, Affiliated Hospital of Fujian University of Traditional Chinese Medicine,Zhangzhou,China
- Author bio：
- Funds：
DOI：10.1007/s11655-011-0780-5
CLC：Published：2011，
Published Online：3 July 2011，
Scan for full text
Hong, Ml., Song, Y. & Li, Xm. Effects and mechanisms of actions of Chinese herbal medicines for asthma., Chin. J. Integr. Med. 17, 483–491 (2011). https://doi.org/10.1007/s11655-011-0780-5
Min-li Hong, Ying Song, Xiu-min Li. Effects and mechanisms of actions of Chinese herbal medicines for asthma. [J]. Chinese Journal of Integrative Medicine 17(7):483-491(2011)
Hong, Ml., Song, Y. & Li, Xm. Effects and mechanisms of actions of Chinese herbal medicines for asthma., Chin. J. Integr. Med. 17, 483–491 (2011). https://doi.org/10.1007/s11655-011-0780-5 DOI：
Min-li Hong, Ying Song, Xiu-min Li. Effects and mechanisms of actions of Chinese herbal medicines for asthma. [J]. Chinese Journal of Integrative Medicine 17(7):483-491(2011) DOI： 10.1007/s11655-011-0780-5.
摘要
Asthma is a chronic inflammatory disorder of airways that affects approximately 300 million adults and children worldwide. Most therapy currently uses bronchodilators and corticosteroids. Systemic side effects from chronic use of these drugs are concern. Chinese medicine (CM) has a long history of human use in China and other Asian countries and well received by the patients. But as one component of Western integrative medicine (WIM)
it is required that CM use is supported by scientific evidence. On the other hand
there are also suggestions that Western standardized medicine should consider personalized practice. In recent years there have been an increasing studies to narrow the gap between CM
the personalized medicine and Western medicine
evidence based medicine. This communication reviews several CM studies published in the English language in details by reviewing the effects and mechanisms of actions on asthma from clinic and experimental studies. Chinese herbal medicines exhibit broad actions on multiple asthma pathologic mechanisms. These mechanisms may involve antiinflammatory and immunomodulatory effects
inhibiting airway remodeling and normalization of hypothalamus
pituitary and adrenal (HPA)-axis disturbances. However
the mechanisms of actions of Chinese herbal medicines for asthma are not fully understood. More controlled clinical studies are warranted and some anti-asthma CM may be proved to be effective when used as monotherapy or complementary asthma therapies.
Abstract
Asthma is a chronic inflammatory disorder of airways that affects approximately 300 million adults and children worldwide. Most therapy currently uses bronchodilators and corticosteroids. Systemic side effects from chronic use of these drugs are concern. Chinese medicine (CM) has a long history of human use in China and other Asian countries and well received by the patients. But as one component of Western integrative medicine (WIM)
it is required that CM use is supported by scientific evidence. On the other hand
there are also suggestions that Western standardized medicine should consider personalized practice. In recent years there have been an increasing studies to narrow the gap between CM
the personalized medicine and Western medicine
evidence based medicine. This communication reviews several CM studies published in the English language in details by reviewing the effects and mechanisms of actions on asthma from clinic and experimental studies. Chinese herbal medicines exhibit broad actions on multiple asthma pathologic mechanisms. These mechanisms may involve antiinflammatory and immunomodulatory effects
inhibiting airway remodeling and normalization of hypothalamus
pituitary and adrenal (HPA)-axis disturbances. However
the mechanisms of actions of Chinese herbal medicines for asthma are not fully understood. More controlled clinical studies are warranted and some anti-asthma CM may be proved to be effective when used as monotherapy or complementary asthma therapies.
关键词
Asthmacomplementary and alternative medicineChinese MedicineChinese Herbal Medicinemechanism of action
Keywords
Asthmacomplementary and alternative medicineChinese MedicineChinese Herbal Medicinemechanism of action
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