Anti-fatigue effect of Renshen Yangrong decoction (人参养荣汤) in mice

Yan-zhi Chen; Fei Lin; Ping-ping Li

doi:10.1007/s11655-011-0879-8

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Anti-fatigue effect of Renshen Yangrong decoction (人参养荣汤) in mice

Updated：2021-08-27

- Anti-fatigue effect of Renshen Yangrong decoction (人参养荣汤) in mice
- Chinese Journal of Integrative Medicine Vol. 17, Issue 10, Pages: 770-774(2011)
- Affiliations：
  
  1. Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Integration of Traditional Chinese and Western Medicine, Peking University School of Oncology, Beijing Cancer Hospital and Institute,Beijing,China
  2. National Institute for the Control of Pharmaceutical and Biological Products,Beijing,China
- Author bio：
- Funds：
  
  Supported by the Fund for Scientific and Technologic Projects from Beijing Administration of Traditional Chinese Medicine (No. 2004 Jing Zhong Zhong IV15)
- DOI：10.1007/s11655-011-0879-8
  CLC：
- Published：2011，
  
  Published Online：26 March 2013，
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Chen, Yz., Lin, F. & Li, Pp. Anti-fatigue effect of Renshen Yangrong decoction (人参养荣汤) in mice., Chin. J. Integr. Med. 17, 770–774 (2011). https://doi.org/10.1007/s11655-011-0879-8

Yan-zhi Chen, Fei Lin, Ping-ping Li. Anti-fatigue effect of Renshen Yangrong decoction (人参养荣汤) in mice. [J]. Chinese Journal of Integrative Medicine 17(10):770-774(2011)
Chen, Yz., Lin, F. & Li, Pp. Anti-fatigue effect of Renshen Yangrong decoction (人参养荣汤) in mice., Chin. J. Integr. Med. 17, 770–774 (2011). https://doi.org/10.1007/s11655-011-0879-8 DOI：

Yan-zhi Chen, Fei Lin, Ping-ping Li. Anti-fatigue effect of Renshen Yangrong decoction (人参养荣汤) in mice. [J]. Chinese Journal of Integrative Medicine 17(10):770-774(2011) DOI： 10.1007/s11655-011-0879-8.

摘要

To explore the anti-fatigue effect of Renshen Yangrong Decoction (人参养荣汤

RYD): in mice. One hundred Kunming mice were randomly divided into 5 groups with 20 mice in each: group. The negative control group was treated with distilled water

the positive control group was treated with Shiyiwei Shenqi Tablet (十一味参芪片

1.0 g/kg)

the high-

medium- and low-dose RYD groups were treated with 42.0

21.0 and 10.5 g/kg of RYD daily

respectively

by gastric infusion. At the end of the 7-day treatment

loaded swimming time

organ wet weight and coefficient

serum glucose

urea nitrogen

and hepatic glycogen levels were determined. The outcomes were compared among groups. As compared with the negative: control group

the loaded swimming time was significantly increased in the positive control group

specifically the medium- and high-dose RYD groups (P<0.01). In addition

the wet weights and coefficients of the spleen and thymus

and the serum glucose and hepatic glycogen contents were increased

whereas serum urea nitrogen level was significantly decreased in the positive control group and the high dose RYD group (P<0.05 or P<0.01). RYD showed an anti-fatigue effect in mice.

Abstract

To explore the anti-fatigue effect of Renshen Yangrong Decoction (人参养荣汤

RYD): in mice. One hundred Kunming mice were randomly divided into 5 groups with 20 mice in each: group. The negative control group was treated with distilled water

the positive control group was treated with Shiyiwei Shenqi Tablet (十一味参芪片

1.0 g/kg)

the high-

medium- and low-dose RYD groups were treated with 42.0

21.0 and 10.5 g/kg of RYD daily

respectively

by gastric infusion. At the end of the 7-day treatment

loaded swimming time

organ wet weight and coefficient

serum glucose

urea nitrogen

and hepatic glycogen levels were determined. The outcomes were compared among groups. As compared with the negative: control group

the loaded swimming time was significantly increased in the positive control group

specifically the medium- and high-dose RYD groups (P<0.01). In addition

the wet weights and coefficients of the spleen and thymus

and the serum glucose and hepatic glycogen contents were increased

whereas serum urea nitrogen level was significantly decreased in the positive control group and the high dose RYD group (P<0.05 or P<0.01). RYD showed an anti-fatigue effect in mice.

关键词

Renshen Yangrong Decoctionanti-fatigueloaded swimming timeurea nitrogenhepatic glycogen

Keywords

Renshen Yangrong Decoctionanti-fatigueloaded swimming timeurea nitrogenhepatic glycogen

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Key laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Integration of Traditional Chinese and Western Medicine, Peking University School of Oncology, Beijing Cancer Hospital & Institute

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