A randomized controlled single-blind clinical trial on 84 outpatients with psoriasis vulgaris by auricular therapy combined with optimized Yinxieling Formula (银屑灵优化方)

Chuan-jian Lu; Yu Xiang; Xiu-li Xie; Mei-ling Xuan; Ze-hui He

doi:10.1007/s11655-012-1020-3

Your Location：

Home >

Browse articles >

A randomized controlled single-blind clinical trial on 84 outpatients with psoriasis vulgaris by auricular therapy combined with optimized Yinxieling Formula (银屑灵优化方)

Updated：2021-08-27

- A randomized controlled single-blind clinical trial on 84 outpatients with psoriasis vulgaris by auricular therapy combined with optimized Yinxieling Formula (银屑灵优化方)
- Chinese Journal of Integrative Medicine Vol. 18, Issue 3, Pages: 186-191(2012)
- Affiliations：
  
  Department of Dermatology, Guangdong Provincial Hospital of Traditional Chinese Medicine,Guangzhou,China
- Author bio：
- Funds：
  
  Supported by the Financial Industry Technology Research and Development Program of Guangdong Province (No. 201105)
- DOI：10.1007/s11655-012-1020-3
  CLC：
- Published：2012，
  
  Published Online：2 April 2012，
Scan for full text
Lu, Cj., Xiang, Y., Xie, Xl. et al. A randomized controlled single-blind clinical trial on 84 outpatients with psoriasis vulgaris by auricular therapy combined with optimized Yinxieling Formula (银屑灵优化方)., Chin. J. Integr. Med. 18, 186–191 (2012). https://doi.org/10.1007/s11655-012-1020-3

Chuan-jian Lu, Yu Xiang, Xiu-li Xie, et al. A randomized controlled single-blind clinical trial on 84 outpatients with psoriasis vulgaris by auricular therapy combined with optimized Yinxieling Formula (银屑灵优化方). [J]. Chinese Journal of Integrative Medicine 18(3):186-191(2012)
Lu, Cj., Xiang, Y., Xie, Xl. et al. A randomized controlled single-blind clinical trial on 84 outpatients with psoriasis vulgaris by auricular therapy combined with optimized Yinxieling Formula (银屑灵优化方)., Chin. J. Integr. Med. 18, 186–191 (2012). https://doi.org/10.1007/s11655-012-1020-3 DOI：

Chuan-jian Lu, Yu Xiang, Xiu-li Xie, et al. A randomized controlled single-blind clinical trial on 84 outpatients with psoriasis vulgaris by auricular therapy combined with optimized Yinxieling Formula (银屑灵优化方). [J]. Chinese Journal of Integrative Medicine 18(3):186-191(2012) DOI： 10.1007/s11655-012-1020-3.

摘要

To explore the therapeutic effect of auricular therapy combined with optimized Yinxieling Formula (银屑灵优化方) on psoriasis vulgaris. A randomized controlled single-blind clinical trial on 84 outpatients with psoriasis vulgaris was conducted. The patients were randomized to a treatment group (43 cases treated by auricular therapy combined with optimized Yinxieling Formula) and a control group (41 cases treated by optimized Yinxieling Formula alone) according to a random number generated by SPSS 17.0 software. The treatment duration for both groups was 8 weeks. The therapeutic effect was comprehensively measured by the primary outcome measure [Psoriasis Area and Severity Index (PASI) reduction rate] and the secondary outcome measure [PASI

Visual Analogue Scale (VAS)

Dermatology Life Quality Index (DLQI)

Self-rating Depression Scale (SDS)

and Self-rating Anxiety Scale (SAS)]. The outcomes of both groups were obtained and compared before and after the intervention. The PASI reduction rate in the treatment group was 74.4% (32/43)

which was higher than that in the control group (36.6%

15/41

P<0.01). The PASI scores decreased in both groups after treatment and was lower in the treatment group compared with the control group P<0.01). With stratified analysis

there were significant differences between the PASI scores in the following subgroups: age 18–30

baseline PASI>10 and stable stage (P<0.05). DLQI decreased in both groups on some categories after treatment

but there were no significant differences between the two groups in SDS

SAS and VAS (P >0.05). No obvious adverse reactions were found in either group. The therapeutic effect of auricular therapy combined with Optimized Yinxieling Formula was superior to Optimized Yinxieling Formula alone with no obvious adverse reaction.

Abstract

Visual Analogue Scale (VAS)

Dermatology Life Quality Index (DLQI)

Self-rating Depression Scale (SDS)

and Self-rating Anxiety Scale (SAS)]. The outcomes of both groups were obtained and compared before and after the intervention. The PASI reduction rate in the treatment group was 74.4% (32/43)

which was higher than that in the control group (36.6%

15/41

P<0.01). The PASI scores decreased in both groups after treatment and was lower in the treatment group compared with the control group P<0.01). With stratified analysis

there were significant differences between the PASI scores in the following subgroups: age 18–30

baseline PASI>10 and stable stage (P<0.05). DLQI decreased in both groups on some categories after treatment

but there were no significant differences between the two groups in SDS

关键词

psoriasis vulgarisauricular therapyoptimized Yinxieling Formulaefficacy

Keywords

psoriasis vulgarisauricular therapyoptimized Yinxieling Formulaefficacy

references

Koo J. Population based epidemiologic study of psoriasis with emphasis on quality of life assessment. Dermatol Clin 1996;14:485–496.

Langley RG, Krueger GG, Griffiths CE. Psoriasis: epidemiology, clinical features, and quality of life. Ann Rheum Dis 2005;64(Suppl) 2:ii18–23.

Ding XL, Wang TL, Shen YW, Wang XY, Zhou C, Tian S, et al. Prevalence of psoriasis in China: an epidemiological survey in six provinces. Chin J Dermatol Venereol (Chin) 2010;24:598–601.

Bao LL, Yang XH. The progress of acupuncture on treating psoriasis. Yunnan Chin Med (Chin) 2010;31(2):69–71.

Wang L, Huang YJ, Wang MH. Clinical observation of Yinxieling Formula for the treatment of psoriasis vulgaris. J Guangzhou Univ Tradit Chin Med (Chin) 2009;26:520–525.

Yan YH, Lu CJ. Optimized Yinxieling for treatment of psoriasis vulgaris: an exploratory clinical trial. Tradit Chin Drug Res Clin Pharmacol (Chin) 2011;22:691–693.

Barker R, Kober A, Hoerauf K, Latzke D, Adel S, Kain ZN, et al. Out-of-hospital auricular acupressure in elder patients with hip fracture: a randomized double-blinded trial. Acad Emerg Med 2006;13:19–23.

Gates S, Smith LA, Foxcroft DR. Auricular acupuncture for cocaine dependence. Cochrane Database Syst Rev. 2006;25(1):CD005192.

Karst M, Winterhalter M, Münte S, Francki B, Hondronikos A, Eckardt A, et al. Auricular acupuncture for dental anxiety: a randomized controlled trial. Anesth Analg 2007;104:295–300.

Liu CF, Yu LF, Lin CH, Lin SC. Effect of auricular pellet acupressure on antioxidative systems in high-risk diabetes mellitus. J Altern Complement Med 2008;14:303–307.

Qing H, Tian YS, Fan JM, Tang BY, Niu HQ, Lu JY. Meridian three-combined therapy for treatment of ordinary psoriasis: a multi-center randomized controlled study. Chin Acupunt Moxibust (Chin) 2009;29:181–184.

Psoriasis Group of Dermatology and Venereology, Chinese Medical Association. Clinical guidelines of psoriasis 2008. Chin J Dermatol (Chin) 2009;42:213–214.

Ashcroft DM, Wan Po AL, Williams HC, Griffiths CE. Clinical measures of disease severity and outcome in psoriasis: a critical appraisal of their quality. Br J Dermatol 1999; 141:185–191.

Flytström I, Stenberg B, Svensson A, Bergbrant IM. Methotrexate vs. ciclosporin in psoriasis: effectiveness, quality of life and safety. A randomized controlled trial. Br J Dermatol 2008;158:116–121.

Lewis V, Finlay AY. Ten years experience of the Dermatology Life Quality Index (DLQI). J Inv Dermatol Symp Proc 2004; 9:169–180.

White S, Vender R, Thaçi D, Haverkamp C, Naeyaert JM, Foster R, et al. Use of calcipotriene cream (Dovonex cream) following acute treatment of psoriasis vulgaris with the calcipotriene/betamethasone dipropionate two-compound product (Taclonex): a randomized, parallel-group clinical trial. Am J Clin Dermatol 2006;7:177–184.

Gina L, Kathy R, Gail S. Alefacept for chronic plaque psoriasis: a selective therapy: clinical efficacy of alefacept. dermatol nurs. 2003;15(3):7–12.

Asher GN, Jonas DE, Coeytaux RR, Reilly AC, Loh YL, Motsinger-Reif AA, Winham SJ. Auriculotherapy for pain management: a systematic review and meta-analysis of randomized controlled trials. J Altern Complement Med 2010;10:1097–1108.

Ma XP. Auricular cutting combined with acupuncture treat 115 patients of psoriasis. Chin Acupunct Moxibust (Chin) 2004;24:254.

Zhang CS, Yang AW, Zhang AL, Fu WB, Thien FU, Lewith G, et al. Ear-acupressure for allergic rhinitis: a systematic review. Clin Otolaryngol 2010;35:6–12.

Yeh ML, Tsou MY, Lee BY, Chen HH, Chung YC. Effects of auricular acupressure on pain reduction in patient-controlled analgesia after lumbar spine surgery. Acta Anaesthesiol Taiwan 2010;48(2):80–86.

Nixon SA, Baetz J. Review of bloodletting and miraculous cures by Vincent Lam. Philosophy Ethics Humanities Med 2007;2:14.

Zhang H, Gu J. Progress of experimental study on treatment of psoriasis by Chinese medicinal monomer and single or compound recipe in Chinese materia medica. Chin J Integr Med 2007;13:312–316.

Xu LP, Bao DH. Therapeutic effect of treating psoriasis by “cutting therapy” at the eardrum. Acta Acad Med CPAPF (Chin) 2006;15:474.

Yin GZ, Zhen LJ. Clinical observation and nursing care of venesection blood letting on treating 72 cases of blood-heat psoriasis. Xinjiang Chin Med (Chin) 2009;27(5):13–15.

FULL TEXT LINK

More>

Views

120

Downloads

CSCD

Alert me when the article has been cited

Submit

Tools

Publicity Resources

Clinical research on acupuncture — Concepts and guidance on efficacy and effectiveness research

Literature research of Chinese medicine recipes for the treatment of psoriasis vulgaris with blood-heat syndrome type

Treatment of advanced non-small cell lung cancer with extracorporeal high frequency thermotherapy combined with Chinese medicine

Clinical observation on effect of triptolide tablet in treating patients with psoriasis vulgaris

Study on compound Salvia pellet in treating hypertensive cerebral hemorrhage

Related Author

No data

Related Institution

Institute for Social Medicine, Epidemiology and Health Economics, Charité University Medical Center

Department of Dermatology, China-Japan Friendship Hospital

Department of Cancer, Guangdong Provincial Hospital of Traditional Chinese Medicine

Institute of Dermatology, Chinese Academy of Medical Sciences, Peking Union Medical College

Department of Neuromedicine, Taizhou Hospital

Address：1 Caochang, xiyuan, Beijing, People's Republic of China Postal code：100091
Tel：010-62886827, 62877592 Fax：010-62874291
Technical support is provided by Beijing Founder electronics co., LTD 京ICP备05067934号-1 京公网安备11010802024621
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰