The use of repeated measures analysis of variance to study the effect of phlegm-heat syndrome on neurological deficits in patients with stroke

Xi-yan Xin; Ying Gao

doi:10.1007/s11655-012-1087-x

Your Location：

Home >

Browse articles >

The use of repeated measures analysis of variance to study the effect of phlegm-heat syndrome on neurological deficits in patients with stroke

Updated：2021-08-27

- The use of repeated measures analysis of variance to study the effect of phlegm-heat syndrome on neurological deficits in patients with stroke
- Chinese Journal of Integrative Medicine Vol. 19, Issue 8, Pages: 568-572(2013)
- Affiliations：
  
  Department of Neurology, Dongzhimen Hospital, Beijing University of Chinese Medicine,Beijing,China
- Author bio：
- Funds：
  
  Supported by the State Administration of Traditional Chinese Medcine of China (No. 200707001), the Major State Basic Research Development Program of China (973 Program, No. 2003CB517102a), the Independent Subject Project of Beijing University of Chinese Medicine (No. 2009JYBZZ-XS060), and the State Major Science and Technology Special Project “Major Creation of New Drugs” (No. 2009ZX09502-028)
- DOI：10.1007/s11655-012-1087-x
  CLC：
- Published：2013，
  
  Published Online：19 May 2012，
Scan for full text
Xin, Xy., Gao, Y. The use of repeated measures analysis of variance to study the effect of phlegm-heat syndrome on neurological deficits in patients with stroke., Chin. J. Integr. Med. 19, 568–572 (2013). https://doi.org/10.1007/s11655-012-1087-x

Xi-yan Xin, Ying Gao. The use of repeated measures analysis of variance to study the effect of phlegm-heat syndrome on neurological deficits in patients with stroke. [J]. Chinese Journal of Integrative Medicine 19(8):568-572(2013)
Xin, Xy., Gao, Y. The use of repeated measures analysis of variance to study the effect of phlegm-heat syndrome on neurological deficits in patients with stroke., Chin. J. Integr. Med. 19, 568–572 (2013). https://doi.org/10.1007/s11655-012-1087-x DOI：

Xi-yan Xin, Ying Gao. The use of repeated measures analysis of variance to study the effect of phlegm-heat syndrome on neurological deficits in patients with stroke. [J]. Chinese Journal of Integrative Medicine 19(8):568-572(2013) DOI： 10.1007/s11655-012-1087-x.

摘要

To explore the effect of phlegm-heat syndrome on the degree of neurological deficit and provide some data support for the correct recognition of the relationship between phlegm-heat syndrome and neurological deficits in stroke patients. Clinical information were collected on 294 patients with acute ischemic stroke (AIS) whose syndrome and National Institute of Health stroke scale (NIHSS) score were checked at baseline (within the first 3-day admission) and at 7

and 90 days after admission to our clinical research centre. We explored the effect of phlegm-heat syndrome on the degree of neurological deficit following stroke by applying a repeated measures analysis of variance. Stroke patients with phlegm-heat syndrome had higher NIHSS score than patients without the syndrome (P <0.01)

and there appeared to be a decrease in NIHSS score over time in all patients (P <0.01). Phlegm-heat syndrome in patients who have suffered stroke has an effect on the degree of neurological deficiency. Disappearance of phlegm-heat syndrome may improve the degree of neurological deficit observed in stroke patients.

Abstract

关键词

ischemic strokephlegm-heat syndromeneurological deficiencyrepeated measures analysis of variance

Keywords

ischemic strokephlegm-heat syndromeneurological deficiencyrepeated measures analysis of variance

references

Zeng DF. Brief discussion of the status and clinical significance of gas of intestines emphraxis in stroke patients. Jilin J Tradit Chin Med (Chin) 1984;12:14–15.

Zou YH. Experience investigation of application of removing phlegm to relax bowels method by professor Wang Yongyan in acute ischemic stroke. J Beijing Univ Tradit Chin Med (Chin) 1999;22(4):68–69.

Ding BG. The clinical and theoretical research on phlegmheat of stroke based on the theory of latent pathogen. Jinan: Shangdong University of Traditional Chinese Medicine Press; 2009:23.

Ding YQ. Exploration on the syndrome differentiation principle of the phlegm-heat and Sthenic-fu type of stroke. Shanxi J Tradit Chin Med (Chin) 2001;17(3):12–13.

Rao ML, ed. The guidelines for prevention and treatment of cerebrovascular disease in China (trial version). Beijing: Ministry of Health of the People’s Republic of China, Neurology Branch of Chinese Medical Association; 2005:30–36.

Acute Encephalopathy Cooperation Group of the State Administration of Traditional Chinese Medicine. Stroke diagnosis and efficacy evaluation criteria (trial). J Beijing Univ Tradit Chin Med (Chin) 1996;19:55–56.

Gao Y, Ma B, Liu Q, Wang YY. Methodological study and establishment of the diagnostic scale for TCM syndromes of ischemic stroke. J Tradit Chin Med (Chin) 2011;52:2097–2101.

Brott T, Adams Jr HP, Olinger CP, Marler JR, Barsan WG, Biller J, et al. Measurements of acute cerebral infarction: a clinical examination scale. Stroke 1989;20:864–870.

Duncan PW, Jorgensen HS, Wade DT. Outcome measures in acute stroke trials: a systematic review and some recommendations to improve practice. Stroke 2000;31:1429–1438.

Xu YY. Medical statistics. Beijing: Higher Education Press; 2001:65–67.

Chen CS, Xu YY, Cao XT. Orthogonal regression models for comparison of unequally-spaced repeated measures data across groups. Chin Health Statistics (Chin) 1996;13:125.

Zhang WT. SPSS statistical analysis (Advanced section). Beijing: Beijing Hope Electronic Press; 2002:36–45.

Yu SL, Xiang HY. Repeated measurement data analysis and SAS program. 1st ed. Beijing: Science Press; 2004:1.

Zhang CL. Clinical and experimental study of Xie Re Hua Tan Fang in treating acute ischemic apoplexy. Jinan: Shangdong University of Traditional Chinese Medicine Press; 2005:3.

Liu C, Gao Y, Zou YH. Clinical application and theoretical innovation of phlegm-heat treatment by removing phlegm to relax bowels method. Chin J Basic Med in Tradit Chin Med (Chin) 2011;17:89–91.

FULL TEXT LINK

More>

Views

1041

Downloads

CSCD

Alert me when the article has been cited

Submit

Tools

Publicity Resources

Cost-effectiveness analysis of combined Chinese medicine and Western medicine for ischemic stroke patients

Exploring molecular mechanism underlying Chinese medicine syndrome: A study on correlation between Chinese medicine syndrome and biomarkers for ischemic stroke

Evaluation of the conjoint efficacy in Chinese medicine with the longitudinal latent variable linear mixed model

Therapeutic effects of traditional herbal medicine on cerebral ischemia: A perspective of vascular protection

Several considerations in using traditional Chinese patent medicine for cerebral infarction

Related Author

No data

Related Institution

Division of Public Health Sciences, Fred Hutchinson Cancer Research Center

School of Public Health, Peking University Health Science Center, Peking University

Neurology Department of Peking University First Hospital, Peking University

Neurology Department of Peking University Third Hospital, Peking University

Department of Hospital Management, Peking University Health Science Center, Peking University

Address：1 Caochang, xiyuan, Beijing, People's Republic of China Postal code：100091
Tel：010-62886827, 62877592 Fax：010-62874291
Technical support is provided by Beijing Founder electronics co., LTD 京ICP备05067934号-1 京公网安备11010802024621
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰