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Influence of Fuzheng Huayu Tablet (扶正化瘀片) on mental state and social function of patients with post-hepatitis B liver cirrhosis
- Chinese Journal of Integrative Medicine Vol. 18, Issue 6, Pages: 466-472(2012)
- Affiliations：
Ruikang Hospital affiliated to Guangxi Traditional Chinese Medicine College,Nanning,China
- Author bio：
- Funds：Supported by Project of Guangxi Science and Technology Department (No. 2010 GXNSFA 013217), Key Project of Guangxi Health Department (No. 2010095) and Guangxi Provincial Fund of Natural Science (No. Gui Ke Zi 0832174)
DOI：10.1007/s11655-012-1112-0
CLC：Published：2012，
Published Online：22 July 2012，
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Deng, X., Liang, J., Wu, Fs. et al. Influence of Fuzheng Huayu Tablet (扶正化瘀片) on mental state and social function of patients with post-hepatitis B liver cirrhosis., Chin. J. Integr. Med. 18, 466–472 (2012). https://doi.org/10.1007/s11655-012-1112-0
Xin Deng, Jian Liang, Fa-sheng Wu, et al. Influence of Fuzheng Huayu Tablet (扶正化瘀片) on mental state and social function of patients with post-hepatitis B liver cirrhosis. [J]. Chinese Journal of Integrative Medicine 18(6):466-472(2012)
Deng, X., Liang, J., Wu, Fs. et al. Influence of Fuzheng Huayu Tablet (扶正化瘀片) on mental state and social function of patients with post-hepatitis B liver cirrhosis., Chin. J. Integr. Med. 18, 466–472 (2012). https://doi.org/10.1007/s11655-012-1112-0 DOI：
Xin Deng, Jian Liang, Fa-sheng Wu, et al. Influence of Fuzheng Huayu Tablet (扶正化瘀片) on mental state and social function of patients with post-hepatitis B liver cirrhosis. [J]. Chinese Journal of Integrative Medicine 18(6):466-472(2012) DOI： 10.1007/s11655-012-1112-0.
摘要
To observe the influence of Fuzheng Huayu Tablet (扶正化瘀片
FZHYT) on mental state and social activity of patients with post-hepatitis B liver cirrhosis (LC-HB). Adopting grouped randomized double-blinded control method
180 LC-HB patients in 3 research centers were distributed to 2 groups
the treated group and the control group
90 in each group. Patients in the treated group were administered with FZHYT; while those in the control group treated with conventional therapy combined with placebo
the course for all patients were 6 months. Their mental state and social activity were evaluated before treatment
after 3 months’ treatment and at terminal of the 6-month therapeutic course by estimating with Zung self-rating anxiety scale (SAS)
self-rating depression scale (SDS) and social deficit screening scale (SDSS). Additionally
the basic demographic materials
liver function
cirrhosis index
hepatic and splenic images
blood coagulation function
etc. in the patients were tested and compared as well. As compared with before treatment
the normal rate of SAS and SDS scores increased and the social deficit rate decreased in the treated group significantly after treatment
showing statistical significance (P<0.05 or P<0.01); while in the control group
change was only shown in the social deficit (P<0.01)
inter-group comparisons after treatment showed significant differences in all the three indexes (P<0.05 or P<0.01). Additionally
after treatment
levels of liver function
cirrhosis
blood coagulation function and splenomegaly in the treated group were all improved significantly P<0.05 or P<0.01)
and the improvements were better than those in the control group (P<0.01) in levels of total bilirubin (TBIL)
albumin (ALB)
type IV collagen (IV-C)
prothrombin time (PT)
prothrombin activity (PTA). Most patients of LC-HB have mental disturbance and social activity deficit
which could definitely be improved by intervention with Chinese FZHYT.
Abstract
To observe the influence of Fuzheng Huayu Tablet (扶正化瘀片
FZHYT) on mental state and social activity of patients with post-hepatitis B liver cirrhosis (LC-HB). Adopting grouped randomized double-blinded control method
180 LC-HB patients in 3 research centers were distributed to 2 groups
the treated group and the control group
90 in each group. Patients in the treated group were administered with FZHYT; while those in the control group treated with conventional therapy combined with placebo
the course for all patients were 6 months. Their mental state and social activity were evaluated before treatment
after 3 months’ treatment and at terminal of the 6-month therapeutic course by estimating with Zung self-rating anxiety scale (SAS)
self-rating depression scale (SDS) and social deficit screening scale (SDSS). Additionally
the basic demographic materials
liver function
cirrhosis index
hepatic and splenic images
blood coagulation function
etc. in the patients were tested and compared as well. As compared with before treatment
the normal rate of SAS and SDS scores increased and the social deficit rate decreased in the treated group significantly after treatment
showing statistical significance (P<0.05 or P<0.01); while in the control group
change was only shown in the social deficit (P<0.01)
inter-group comparisons after treatment showed significant differences in all the three indexes (P<0.05 or P<0.01). Additionally
after treatment
levels of liver function
cirrhosis
blood coagulation function and splenomegaly in the treated group were all improved significantly P<0.05 or P<0.01)
and the improvements were better than those in the control group (P<0.01) in levels of total bilirubin (TBIL)
albumin (ALB)
type IV collagen (IV-C)
prothrombin time (PT)
prothrombin activity (PTA). Most patients of LC-HB have mental disturbance and social activity deficit
which could definitely be improved by intervention with Chinese FZHYT.
关键词
post-hepatitis B liver cirrhosisFuzheng Huayu Tabletmental statesocial activity
Keywords
post-hepatitis B liver cirrhosisFuzheng Huayu Tabletmental statesocial activity
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