FOLLOWUS
Natural products: A safest approach for obesity
- Chinese Journal of Integrative Medicine Vol. 18, Issue 6, Pages: 473-480(2012)
- Affiliations：
Department of Pharmaceutical Sciences, Guru Jambheshwar, University of Science and Technology, Hisar,India
- Author bio：
- Funds：
DOI：10.1007/s11655-012-1120-0
CLC：Published：2012，
Published Online：22 July 2012，
Scan for full text
Vasudeva, N., Yadav, N. & Sharma, S.K. Natural products: A safest approach for obesity., Chin. J. Integr. Med. 18, 473–480 (2012). https://doi.org/10.1007/s11655-012-1120-0
Neeru Vasudeva, Neerja Yadav, Surendra Kumar Sharma. Natural products: A safest approach for obesity. [J]. Chinese Journal of Integrative Medicine 18(6):473-480(2012)
Vasudeva, N., Yadav, N. & Sharma, S.K. Natural products: A safest approach for obesity., Chin. J. Integr. Med. 18, 473–480 (2012). https://doi.org/10.1007/s11655-012-1120-0 DOI：
Neeru Vasudeva, Neerja Yadav, Surendra Kumar Sharma. Natural products: A safest approach for obesity. [J]. Chinese Journal of Integrative Medicine 18(6):473-480(2012) DOI： 10.1007/s11655-012-1120-0.
摘要
Obesity is recognized as a social problem
associated with serious health risks and increased mortality. Numerous trials have been conducted to find and develop new anti-obesity drugs through herbal sources to minimize adverse reactions associated with the present anti-obesity drugs. The use of natural products as medicine has been documented for hundreds of years in various traditional systems of medicines throughout the world. This review focuses on the medicinal plants such as Achyranthus aspera
Camellia sinensis
Emblica officinalis
Garcinia cambogia
Terminalia arjuna
etc.
being used traditionally in Ayurvedic
Unani
Siddha and Chinese
etc.
systems of medicine. The review also highlights recent reported phytochemicals such as escins
perennisosides
dioscin
gracillin
etc.
and the various extracts of the plants like Nelumbo nucifera
Panax japonicas
Cichorium intybus
Cyperus rotundus
Paeonia suffruticosa
etc.
which have been successfully identified for the treatment of obesity.
Abstract
Obesity is recognized as a social problem
associated with serious health risks and increased mortality. Numerous trials have been conducted to find and develop new anti-obesity drugs through herbal sources to minimize adverse reactions associated with the present anti-obesity drugs. The use of natural products as medicine has been documented for hundreds of years in various traditional systems of medicines throughout the world. This review focuses on the medicinal plants such as Achyranthus aspera
Camellia sinensis
Emblica officinalis
Garcinia cambogia
Terminalia arjuna
etc.
being used traditionally in Ayurvedic
Unani
Siddha and Chinese
etc.
systems of medicine. The review also highlights recent reported phytochemicals such as escins
perennisosides
dioscin
gracillin
etc.
and the various extracts of the plants like Nelumbo nucifera
Panax japonicas
Cichorium intybus
Cyperus rotundus
Paeonia suffruticosa
etc.
which have been successfully identified for the treatment of obesity.
关键词
AyurvedaChinese MedicineobesitySiddhaUnani medicine
Keywords
AyurvedaChinese MedicineobesitySiddhaUnani medicine
references
Hu JN, Zhu XM, Han LK, Saito M, Sun YS, Yoshikawa M, et al. Anti-obesity effects of escins extracted from the seeds of Aesculus turbinata Blume (Hippocastanaceae). Chem Pharm Bull 2008;56(1):12–16.
Dickel ML, Rates SMK, Ritter MR. Plants popularly used for loosing weight purposes in Porto Alegre, South Brazil. J Ethnopharmacol 2007;109:60–71.
Kwon CS, Sohn HY, Kim SH, Kim JH, Son KH, Lee JS, et al. Anti-obesity effect of Dioscorea nipponica Makino with lipase-inhibitory activity in rodents. Biosci Biotechnol Biochem 2003;67:1451–1456.
Bojrab GG. Composition for treatment of obesity. US Patent 6641808 B1,4 Nov 2003.
Patwardhan B, Warude N, Pushpangadan P, Bhatt N. Ayurveda and traditional Chinese medicine: a comparative overview. Evid Based Compl Altern Med 2005;2:465–473.
Boyer R. Concept of Biochemistry. USA: The Wadsworth Group Library of Congress, 2002.
Brown W. Virgil Niacin for lipid disorder. Post Graduate Med 1945;98:185.
Mukherjee PK, Wahile A. Integrated approaches towards drug development from Ayurveda and other Indian system of medicines. J Ethnopharmacol 2006;103:25–35.
Flaws B. New approaches to the Chinese medical treatment of obesity. Acupunct Today 2002;10:3.
Block EF. TCM concepts of obesity. www.diamondhead.net/tcmobesity.htm. 2007.
Birari RB, Bhutani KK. Pancreatic lipase inhibitors from natural sources: unexplored potential. Drug Discov Today 2007;12:879–889.
Bhutani KK, Birari R, Kapat K. Potential anti-obesity and lipid lowering natural products: a review. Nat Product Commun 2007;2:331–348.
Khare CP. Indian medicinal plants: an illustrated dictionary. New Delhi: Springer private limited; 2007:11.
Kim HY. Effects of Onion (Allium cepa) skin extract on pancreatic lipase and body weight-related parameters. Food Sci Biotech 2007;16:434–438.
Misra BS. Bhavaprakasa. Banaras: Jaya Krishna Das Haridas Gupta; 1949:220.
Parrotta JA. Healing plants of peninsular india. Wallingford: CABI Publishing, CAB international, UK; 2001:649,580.
Jellin JM, Batz F, Hitchens K. Pharmacist’s letter/Prescriber’s letter Natural Medicines comprehensive database. Stockton, Ca: Therapeutic Research faculty; 1999:1011–1013.
Silvas UJE, Cani PD, Delmee E, Neyrinck A, Lopez MG, Delzenne MN. Physiological effects of dietry fructans extracted from Agave tequilana and Dasylirion spp. Br J Nutr 2007;99:254–261.
Moro CO, Basile G. Obesity and medicinal plants. Fitoterapia 2000;71:73–82.
Dermarderosian A. A guide to popular natural products. Facts and comparisons. LA: J.A.Majors Publisher; 1999:134–135.
Phyllis A, Balch, James F, Balch M. Prescrisption for natural healing. New York: New York Penguin Putnam Inc.; 2000:540–547.
Larosa JC, Gotto AM. Past, present and future standards for management of dyslipidaemia. Am J Med 2004;115:375.
Kritikar KR, Basu BD. Indian medicinal plants. 2nd ed. Dehradun: Bishan Singh/Mahender Pal Singh; 1975:2066–2068.
Gao X, Dang Y. Traditional Chinese medical beauty care. Perking: China Science and Technology Press; 2000:305–306.
Liu C, Tseng A. Chinese herbal medicine. Boca Raton: CRC Press; 2005:387–388.
Li Y, Huang TH, Yamahara. Salacia root, a unique Ayurvedic medicine, meets multiple targets in diabetes and obesity. J Life Sci 2008;82:1045–1049.
Kirmani Nafees bin Auz. Sharh -e-Asbab wa Alamat. Translated by Hakeem Ayoub Israili, Lucknow: Munshi Nawal Kishor. 1918:523.
Yoshizumi K, Hirano K, Ando H, Hirai Y, Ida Y, Tsuji T, et al. Lupane-type saponins from leaves of Acanthopanax sessiliflorus and their inhibitory activity on pancreatic lipase. J Agric Food Chem 2006;54:335–341.
Kim MJ, Park MH, Jeong MK, Yeo JD, Cho W-II, Chang PS, et al. Radical scavenging activity and anti-obesity effects in 3T3-L1 preadipocyte differentiation of Ssuk (Artemisia princeps Pamp.) extract. Food Sci Biotechnol 2010;19:535–540.
Morikawa T, Muraoka O, Yoshikawa M. Pharmaceutical food science; search for anti-obese constituents from the flowers of Bellis perennis. Yakugaku Zasshi 2010;130:673–678.
Lemhadri A, Eddouks M, Sulpice T, Burcelin R. Antihyperglycaemic and anti-obesity effects of Capparis spinosa and Chamaemelum nobile aqueous extracts in high fat diet mice. Am J Pharmacol Toxicol 2007;2:106–110.
Yamamoto M, Shimura S, Itoh Y, Ohaska T, Egawa M, Inoue S. Anti-obesity effects of lipase inhibitor CT-II, an extract from edible herbs, Nomame Herba, on rats fed a high-fat diet. Int J Obes Relat Metab Disord 2000;24:758–764.
Hatano T, Yamashita A, Hashimoto Y, Ito H, Kubo N, Yoshiyama M, et al. Flavan dimmers with lipase inhibitory activity from Cassia nomame. Phytochemistry 1997;46:893–900.
Lamiaa AA, Reham SR, Reham AM. Biochemical and histopathological studies on the water extracts of Marjoram and Chicory herbs and their mixture in obese rats. Pakistan J Nutr 2009;8:1581–1587.
Oben J, Kuate D, Agbor G, Momo C, Talla X. The use of a Cissus Quadrangularis formulation in the management of weight loss and metabolic syndrome. Lipid Health Dis 2006;5:24.
Kim SO, Yun SJ, Lee EH. The water extract of adlay seed (Coix lachrymajobi var. mayuen) exhibits anti-obesity effects through neuroendocrine modulation. Am J Chin Med 2007;35:297–308.
Kim SO, Yun SJ, Jung B, Lee EH, Hahm DH, Shim I, et al. Hypolipidemic effects of crude extract of adlay seed (Coix lachrymajobi Var. mayuen) in obesity rat fed high fat diet: relation of TNF-α and leptin mRNA expressions and serum lipid levels. Life Sci 2004;75:1391–1404.
Lemaure B, Touche A, Zbinden I, Moulin J, Courtois D, Mace K, et al. Administration of Cyperus rotundus tubers extract prevents weight gain in obese Zucker rats. Phytother Res 2007;21:724–730.
Lien DN, Quynh NT, Quang NH, Phuc DV, Ngan NTT. Anti-obesity and body weight reduction effect of Fortunella japonica peel extract fractions in experimentally obese mice. KKU Sci J 2009;37:96–104.
Palit P, Furman BL, Gray AI. Novel weight-reducing activity of Galega officinalis in mice. J Pharm Pharmacol 1999;51:1313–1319.
Oluyemi KA, Omotuyi IO, Jimoh OR, Adesanya OA, Saalu CL, Josiah SJ. Erythropoietic and anti-obesity effects of Garcinia cambogia (bitter kola) in wister rats. Biotechnol Appl Biochem 2007;46:69–72.
Roongpisuthipong C, Kantawan R, Roongpisuthipong W. Reduction of adipose tissue and body weight: effect of water soluble calcium hydroxycitrate in Garcinia atroviridis on the short term treatment of obese women in Thailand. Asia Pac J Clin Nutr 2007;16:25–29.
Kamisoyama H, Honda K, Tominaga Y, Yokota S, Hasegawa S. Investigation of the anti-obesity action of licorice flavonoid oil in diet-induced obese rats. Biosci Biotechnol Biochem 2008;72:3225–3231.
Bose M, Lambert JD, Ju J, Reuhl KR, Shapses SA, Yang CS. The major green tea polyphenol, (−)-epigallocatechin-3-gallate, inhibits obesity, metabolic syndrome, and fatty liver disease in high-fat-fed mice. J Nutr 2008;138:1677–1683.
Han LK, Takaku T, Li J, Kimura Y, Okuda H. Anti-obesity action of oolong tea. Int J Obes Relat Metab Disord 1999;23(1):98–105.
Masaaki N, Yuko F, Sumio A, Yoshiko TO, Takashi I, Hiroshi S, et al. Inhibitory effects of Oolong tea polyphenols on pancreatic lipase in vitro. J Agric Food Chem 2005;53:4593–4598.
Ono Y, Hattori E, Fukaya Y, Imai S, Ohizumi Y. Anti-obesity effect of Nelumbo nucifera leaves extract in mice and rats. J Ethnopharmacol 2006;106:238–244.
Nagasawa H, Iwabuchi T, Inatomi H. Protection by treepeony (Paeonia suffruticosa Andr) of obesity in (SLN × C3H/He) F1 obese mice. In Vivo 1991;5:115–118.
Kim JH, Hahm DH, Yang DC, Kim JH, Lee HJ, Shim I. Effect of crude saponin of Korean red ginseng on high-fat diet induced obesity in the rat. J Pharmacol Sci 2005;97:124–131.
Han LK, Zheng YN, Yoshikawa M, Okuda H, Kimura Y. Antiobesity effects of chikusetsusaponins isolated from Panax japonicus rhizomes. BMC Compl Altern Med 2005;5:9.
Liu W, Zheng Y, Han L, Wang H, Satio M, Ling M, et al. Saponins (Ginsenosides) from stems and leaves of Panax quinquefolium prevented high-fat diet-induced obesity in mice. Phytomed 2008;15:1140–1145.
Zhao HL, Harding SV, Marinangeli CP, Kim YS, Jones PJ. Hypocholesterolemic and anti-obesity effects of saponins from Platycodon grandiflorum in hamsters fed atherogenic diets. J Food Sci 2008;73:195–200.
Zao HL, Kim YS. Determination of the kinetic properties of platycodin D for the inhibition of pancreatic lipase using a 1,2-diglyceride-based colorimetric assay. Arch Pharm Res 2004;27:968–972.
Lei F, Zhang XN, Wang W, Xing DM, Xie WD, Su H, et al. Evidence of anti-obesity effects of the pomegranate leaf extract in high-fat diet induced obese mice. Int J Obes (Lond) 2007;31:1023–1029.
Ninomiya K, Matsuda H, Kubo M, Morikawa T, Nishida N, Yoshikawa M. Potent anti-obese principle from Rosa canina: structural requirements and mode of action of transtiliroside. Bioorg Med Chem Lett 2007;17:3059–3064.
Yoshikawa M, Shimoda H, Nishida N, Takada M, Matsuda H. Salacia reticulata and its polyphenolic constituents with lipase inhibitory and lipolytic activities have mild antiobesity effects in rats. J Nutr 2002;132:1819–1824.
Han LK, Sumiyoshi M, Zhang J, Liu MX, Zhang XF, Zheng YN, et al. Anti-obesity action of Salix matsudana leaves (Part 1). Anti-obesity action by polyphenols of Salix matsudana in high fat-diet treated rodent animals. Phytother Res 2003;17:1188–1194.
Yan JB, Jing L, Wang JB, Ding YH, Zheng TZ, Qu SY, et al. Inhibitive effect of Semen cassiae on the weight gain in rats with nutritive obesity. J Chin Med Mater (Chin) 2004;27:281–284.
Zhang J, Kang MJ, Kim MJ, Kim ME, Song JH, Lee YM, et al. Pancreatic lipase inhibitory activity of taraxacum officinale in vitro and in vivo. Nutr Res Pract 2008;2:200–203.
Handa T, Yamaguchi K, Sono Y, Yazawa K. Effects of fenugreek seed extract in obese mice fed a high-fat diet. Biosci Biotechnol Biochem 2005;69:1186–1188.
Han LK, Gong XJ, Kawano S, Saito M, Kimura Y, Okuda H. Antiobesity actions of Zingiber officinale Roscoe. Yakugaku Zasshi 2005;125:213–217.
Yun SN, Moon SJ, Ko SK, Im BO, Chung SH. Wild ginseng prevents the onset of high-fat diet induced hyperglycemia and obesity in ICR mice. Arch Pharm Res 2004;27:790–796.
0
Views
119
Downloads
36
CSCD
- Meta-XMLDownload
- BibTeXDownload
- EndnoteDownload
- RefMan Download
- NoteExpressDownload
- NoteFirstDownload
Publicity Resources
Related Articles
Related Author
Related Institution
- Address：1 Caochang, xiyuan, Beijing, People's Republic of China Postal code：100091
- Tel：010-62886827, 62877592 Fax：010-62874291
- Technical support is provided by Beijing Founder electronics co., LTD 京ICP备05067934号-1
京公网安备11010802024621 - It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
- Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.
