FOLLOWUS
Application of chinese herbal medicines to revitalize adult stem cells for tissue regeneration
- Chinese Journal of Integrative Medicine Vol. 18, Issue 12, Pages: 903-908(2012)
- Affiliations：
1. Institute of Chinese Medicine, The Chinese University of Hong Kong,Hong Kong,China
2. State Key Laboratory of Phytochemistry and Plant Resources in West China, The Chinese University of Hong Kong,Hong Kong,China
3. Jockey Club Centre for Osteoporosis Care and Control, The Chinese University of Hong Kong,Hong Kong,China
4. Department of Orthopaedics and Traumatology, the Chinese University of Hong Kong,Hong Kong,China
- Author bio：
- Funds：
DOI：10.1007/s11655-012-1293-3
CLC：Published：2012，
Published Online：13 December 2012，
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Wong, HL., Siu, Ws., Shum, Wt. et al. Application of chinese herbal medicines to revitalize adult stem cells for tissue regeneration., Chin. J. Integr. Med. 18, 903–908 (2012). https://doi.org/10.1007/s11655-012-1293-3
Hing-Lok Wong, Wing-sum Siu, Wai-ting Shum, et al. Application of chinese herbal medicines to revitalize adult stem cells for tissue regeneration. [J]. Chinese Journal of Integrative Medicine 18(12):903-908(2012)
Wong, HL., Siu, Ws., Shum, Wt. et al. Application of chinese herbal medicines to revitalize adult stem cells for tissue regeneration., Chin. J. Integr. Med. 18, 903–908 (2012). https://doi.org/10.1007/s11655-012-1293-3 DOI：
Hing-Lok Wong, Wing-sum Siu, Wai-ting Shum, et al. Application of chinese herbal medicines to revitalize adult stem cells for tissue regeneration. [J]. Chinese Journal of Integrative Medicine 18(12):903-908(2012) DOI： 10.1007/s11655-012-1293-3.
摘要
It has been established in the recent several decades that adult stem cells play a crucial role in tissue renewal and regeneration. Adult stem cells locate in certain organs can differentiate into functional entities such as macrophages and bone cells. Hematopoietic stem cells (HSCs) and mesenchymal stem cells (MSCs) are two of the most important populations of adult stem cells. The application of these stem cells offers a new insight in treating various pathological conditions
through replenishing cells of specific functions by turning on or off the differentiating program within quiescent stem cell niches. Apart from that
they are also capable to travel through the circulation
migrate to injury sites and differentiate to enhance regeneration process. Recently
Chinese medicine (CM) has shown to be potential candidates to activate adult stem cells for tissue regeneration. This review summarizes our own
as well as others’ findings concerning the use of Chinese herbal medicine in the regulation processes of adult stem cells differentiation and their movement in tissue repair and rejuvenation. A number of Chinese herbs are used as therapeutic agents and presumably preventive agents on metabolic disorders. In our opinion
the activation of adult stem cells self-regeneration not only provides a novel way to repair tissue damage
but also reduces the use of targeted drug that adversely altering the normal metabolism of human subjects.
Abstract
It has been established in the recent several decades that adult stem cells play a crucial role in tissue renewal and regeneration. Adult stem cells locate in certain organs can differentiate into functional entities such as macrophages and bone cells. Hematopoietic stem cells (HSCs) and mesenchymal stem cells (MSCs) are two of the most important populations of adult stem cells. The application of these stem cells offers a new insight in treating various pathological conditions
through replenishing cells of specific functions by turning on or off the differentiating program within quiescent stem cell niches. Apart from that
they are also capable to travel through the circulation
migrate to injury sites and differentiate to enhance regeneration process. Recently
Chinese medicine (CM) has shown to be potential candidates to activate adult stem cells for tissue regeneration. This review summarizes our own
as well as others’ findings concerning the use of Chinese herbal medicine in the regulation processes of adult stem cells differentiation and their movement in tissue repair and rejuvenation. A number of Chinese herbs are used as therapeutic agents and presumably preventive agents on metabolic disorders. In our opinion
the activation of adult stem cells self-regeneration not only provides a novel way to repair tissue damage
but also reduces the use of targeted drug that adversely altering the normal metabolism of human subjects.
关键词
adult stem cellTraditional Chinese MedicineHematopoietic Stem Cellmesenchymal stem cellcirculating mesenchymal stem cells
Keywords
adult stem cellTraditional Chinese MedicineHematopoietic Stem Cellmesenchymal stem cellcirculating mesenchymal stem cells
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