Study on the relationship between chinese medicine constitutive susceptibility and diversity of syndrome in diabetic nephropathy

Xin Mou; Di-yi Zhou; Wen-hong Liu; Dan-yang Zhou; Ying-hui Liu; Yong-bin Hu; Cheng-min Shou; Jia-wei Chen; Jin-xi Zhao; Guo-ling Ma

doi:10.1007/s11655-013-1411-0

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Study on the relationship between chinese medicine constitutive susceptibility and diversity of syndrome in diabetic nephropathy

Updated：2021-08-27

- Study on the relationship between chinese medicine constitutive susceptibility and diversity of syndrome in diabetic nephropathy
- Chinese Journal of Integrative Medicine Vol. 19, Issue 9, Pages: 656-662(2013)
- Affiliations：
  
  1. Department of Endocrinology, Hangzhou Red-Cross Hospital,Hangzhou,China
  2. Dongzhimen Hospital, Beijing University of Chinese Medicine,Beijing,China
  3. Zhejiang University of Traditional Chinese Medicine,Hangzhou,China
- Author bio：
- Funds：
  
  Supported by the National Natural Science Foundation of China (No.30801467, No. 81273623) and the Natural Science Foundation of Zhejiang Province (No.Y2080683)
- DOI：10.1007/s11655-013-1411-0
  CLC：
- Published：2013，
  
  Published Online：10 April 2013，
Scan for full text
Mou, X., Zhou, Dy., Liu, Wh. et al. Study on the relationship between chinese medicine constitutive susceptibility and diversity of syndrome in diabetic nephropathy., Chin. J. Integr. Med. 19, 656–662 (2013). https://doi.org/10.1007/s11655-013-1411-0

Xin Mou, Di-yi Zhou, Wen-hong Liu, et al. Study on the relationship between chinese medicine constitutive susceptibility and diversity of syndrome in diabetic nephropathy. [J]. Chinese Journal of Integrative Medicine 19(9):656-662(2013)
Mou, X., Zhou, Dy., Liu, Wh. et al. Study on the relationship between chinese medicine constitutive susceptibility and diversity of syndrome in diabetic nephropathy., Chin. J. Integr. Med. 19, 656–662 (2013). https://doi.org/10.1007/s11655-013-1411-0 DOI：

Xin Mou, Di-yi Zhou, Wen-hong Liu, et al. Study on the relationship between chinese medicine constitutive susceptibility and diversity of syndrome in diabetic nephropathy. [J]. Chinese Journal of Integrative Medicine 19(9):656-662(2013) DOI： 10.1007/s11655-013-1411-0.

摘要

To explore the relationship between Chinese medicine (CM) constitutive susceptibility and syndrome diversity in diabetic nephropathy (DN). Epidemiologic investigation on constitution adopting the “Constitution in Chinese Medicine Questionnaire” (CCMQ)

and survey on syndrome type by CM syndrome scale (preliminary) were carried out in 180 DN patients. Cluster analysis on symptom items was used to determine the syndrome type

and canonical correlation analysis was used to analyze the relationship between patients’ constitution and syndrome. Baseline levels in all enrolled patients were not different statistically. Cluster analysis showed 8 syndromes existed in DN patients

namely: I

qi-yin deficiency with qistagnancy type; II

yin-yang deficiency with heat-water-blood stasis type; III

qi-yin deficiency with dampnessheat type; IV

yin-yang deficiency with blood-stasis and heat type; V

qi-yin deficiency with stagnant heat type; VI

yin-yang deficiency with inner dampness-heat stagnancy type; VII

yin deficiency with heat stagnancy type; and VIII

Kidney (Shen)-Spleen (Pi) deficiency with stagnant heat type. Correlation analysis on the 8 syndromes and the 9 constitutions showed statistical significant correlations between syndrome III and dampness-heat constitution (P=0.0001); syndrome IV and blood-stasis constitution (P=0.0001); and syndrome VII and yin-deficiency constitution (P=0.0180). Certain relationship revealed between CM constitutions and syndrome types; constitution decides the disease genesis

its syndrome type and prognosis

as well as the change of syndromes.

Abstract

and survey on syndrome type by CM syndrome scale (preliminary) were carried out in 180 DN patients. Cluster analysis on symptom items was used to determine the syndrome type

namely: I

qi-yin deficiency with qistagnancy type; II

yin-yang deficiency with heat-water-blood stasis type; III

qi-yin deficiency with dampnessheat type; IV

yin-yang deficiency with blood-stasis and heat type; V

qi-yin deficiency with stagnant heat type; VI

yin-yang deficiency with inner dampness-heat stagnancy type; VII

yin deficiency with heat stagnancy type; and VIII

its syndrome type and prognosis

as well as the change of syndromes.

关键词

diabetic nephropathyChinese medicine constitutionsyndromatologic study

Keywords

diabetic nephropathyChinese medicine constitutionsyndromatologic study

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Related Institution

Department of Endocrinology of Hangzhou Red Cross Hospital

Zhejiang University of Chinese Medicine

Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine

Department of Pharmacy, College of Chemical and Chemistry Engineering, Hu’nan University

Department of Pharmacology, College of Pharmaceutical Sciences, Zhejiang University of Technology

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