FOLLOWUS
Advances and challenges in screening traditional Chinese anti-aging materia medica
- Chinese Journal of Integrative Medicine Vol. 19, Issue 4, Pages: 243-252(2013)
- Affiliations：
1. Xiyuan Hospital, China Academy of Chinese Medical Sciences,Beijing,China
2. Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing,China
3. Fengsheng Orthopedics Specialist Hospital,Beijing,China
- Author bio：
- Funds：
DOI：10.1007/s11655-013-1432-8
CLC：Published：2013，
Published Online：2 April 2013，
Scan for full text
Li, Cs., Deng, Hb., Li, Dd. et al. Advances and challenges in screening traditional Chinese anti-aging materia medica., Chin. J. Integr. Med. 19, 243–252 (2013). https://doi.org/10.1007/s11655-013-1432-8
Chun-sheng Li, Hong-bin Deng, Dian-dong Li, et al. Advances and challenges in screening traditional Chinese anti-aging materia medica. [J]. Chinese Journal of Integrative Medicine 19(4):243-252(2013)
Li, Cs., Deng, Hb., Li, Dd. et al. Advances and challenges in screening traditional Chinese anti-aging materia medica., Chin. J. Integr. Med. 19, 243–252 (2013). https://doi.org/10.1007/s11655-013-1432-8 DOI：
Chun-sheng Li, Hong-bin Deng, Dian-dong Li, et al. Advances and challenges in screening traditional Chinese anti-aging materia medica. [J]. Chinese Journal of Integrative Medicine 19(4):243-252(2013) DOI： 10.1007/s11655-013-1432-8.
摘要
To provide a better service for senior health care
we summarized screening studies of traditional Chinese anti-aging materia medica (TCAM). We collected and analyzed literature of TCAM screening studies using the lifespan test and animal models of aging from 1984 to 2012. We found 26 screening methods for TCAM
and 153 single herbs or active ingredients of TCAM that have been screened out during the past 28 years. The cell lifespan test
the fruit fly lifespan test
and D-galactose aging model were the most widely used and intensively studied screening methods. However
the method for establishing the D-galactose aging model needs to be standardized
and the D-galactose aging model cannot completely be a substitute for the normal aging mouse model. Great success has been achieved in screening studies in TCAM. To further improve screening studies in TCAM
we suggest that the D-galactose aging model be incorporated into the lifespan test in the New Drugs of Traditional Chinese Medicine Research Guide.
Abstract
To provide a better service for senior health care
we summarized screening studies of traditional Chinese anti-aging materia medica (TCAM). We collected and analyzed literature of TCAM screening studies using the lifespan test and animal models of aging from 1984 to 2012. We found 26 screening methods for TCAM
and 153 single herbs or active ingredients of TCAM that have been screened out during the past 28 years. The cell lifespan test
the fruit fly lifespan test
and D-galactose aging model were the most widely used and intensively studied screening methods. However
the method for establishing the D-galactose aging model needs to be standardized
and the D-galactose aging model cannot completely be a substitute for the normal aging mouse model. Great success has been achieved in screening studies in TCAM. To further improve screening studies in TCAM
we suggest that the D-galactose aging model be incorporated into the lifespan test in the New Drugs of Traditional Chinese Medicine Research Guide.
关键词
Chinese anti-aging materia medicalifespan testanimal model of agingscreening research
Keywords
Chinese anti-aging materia medicalifespan testanimal model of agingscreening research
references
Shen ZY. Anti-aging effect of the extracts of Korea Epimedium EF. Traditional medicine and human health. 1st ed. Beijing: Traditional Chinese Medicine Ancient Books Publishing House; 2004:19–22.
Zhong X, Yu L. Study on mechanism of pine pollen resisting cell replicative senescence in fibroblast. Chin J Gerontol (Chin) 2009;29:1904–1907.
Tong TJ, Zhang ZY. Tendency analysis of modern basic aging research. Conference proceedings of 3rd academic conference of China aging and anti-aging association; 2011:1–4.
Liu P, Ge YX, Sun H, Huo YS. Dose-effect relationship of different components of ginseng saponins on cultured cells. Chin J Gerontol (Chin) 1989; 9:242–245.
Wang F, Zhang YQ. Advances in pharmacology research of anti-aging Chinese medicines. LiShiZhen Med Mater Med Res (Chin) 2002;13:236–237.
Yin ZR, Zhou SR. Ten year’s pharmacological research of Gynostemma. Jiangxi Tradit Chin Med (Chin) 1988;21(6):54–55.
Liu B, Situ ZQ, Wu JZ, Zhao RF, Chen JY. Effects of Lycium barbarum L and Drynaria fortune (Kunne) J Sm on the Lifetime of Human Gingival Fibroblasts-an in vitro study. Chin J Gerontol (Chin) 1993;13:296–297.
Yang CY. Current advances in the anti-aging effect of Polygonium Multiflorum. LiShiZhen Med Materia Med Res (Chin) 1999;10:390–391.
Huang JX, Xin JL, Ye TT, Fu H, Ma YY, Wu KG, et al. Effect of passionflower on DNA synthesis of cultured Diploin cells in vitro. Chin J Gerontol (Chin) 1994; 14:292–293.
Zhang GX, Tao GZ, Chen KJ. Conference proceedings of 2nd Chinese basic geriatrics. Geriatrics society of Chinese medical association, Chin J Geriatr (Chin) 1997;16(5):5–6.
Conference proceedings of senescence mechanism and countermeasures. Geriatrics society of Chinese medical association; 1991:143.
Dong Q, Wu M, Qu WM, Dou J. Anti-aging effect of prescription of TCAM Astragalus. Chin J Gerontol (Chin) 1996;16:376–377.
Zhang LZ, Zhao BL. Tea Polyphenol EGCG prolongs the life of C. elegans under heat and oxidative stress conditions. Conference proceedings of 3rd aging and antiaging gerontological society of China; 2011:185.
Chen QY, Ji YT, Sun YL. Biological effect of Fiveleaf Gynostemma (Cynostemma pentaphyllum) on thorny nude Belly Water Flea-a model for the screening of anti-aging. Chin Tradit Herbal Drug (Chin) 1995;26:527–528.
Chen KJ, Li CS. Current developments of traditional Chinese anti-aging materia medica, advances in Chinese medicine and pharmacy at home and abroad. State Administration of Traditional Chinese Medicine of China; 1990:17–26.
Li CS, Hou RX. Ten years survey of lifespan test and animal model of aging applied for evaluating the antiaging effect of Traditional Chinese Medicine. 1998 annual meeting of academic committee of geriatrics, hold by Beijing Association of the Integration of Traditional and Western Medicine; 1999:1–9.
Jin DS, Zhou JQ, Cui DW. Effects of Maifan stone on the life-span and free radicals in the brain of housefly. Chin J Gerontol (Chin) 1988;8:104–106.
Liu YL, Liu YS, Mu XS, Qian L, Ren X, Hou ZR, et al. The anti-aging effect of Oviductus Ranae. J Shenyang Pharma Univ (Chin) 1998;15(1):56–58.
Li CH, Li Y, Li XF, Li Y. Anti-aging action of Radix adrenophorae potaninii korsh polysaccharides in mice and fruit-flies. Chin Pharmacol Bull (Chin) 2002;18:452–455.
Dai SZ, Wen RL, Li W, Ma Y, Pei XY, Zhao XH, et al. The values of Lycium Barbarum L to human being in antisenility and prolonging life-span. Chin J Gerontol (Chin) 1994;14(1):33–36.
Sun JL, Sui DY, Yu XF, Lu ZZ. Anti-aging actions of coarse polysaccharide from fruit of ginseng (CPFG). Chin J Gerontol (Chin) 1999;19:356–357.
Wang W, Chen KJ. Survey and prospect in integration of traditional and Western medicine in the lifespan test. Conference proceedings of traditional geriatrics, part II, published by Xiyuan Hospital, China Academy of Chinese Medical Sciences; 1984:51–54.
Chen KJ, Li CS. New anti-aging drugs of traditional Chinese medicine. 1st ed. Beijing: People’s Medical Publishing House; 1998:328.
Jiang WZ, Zhang HQ. Anti-aging effect of polypeptides from Fructus Lycii on D-gal-induced aging model mice and the possible mechanism. Int J Pharma Res (Chin) 2010;37(1):49–50.
Wei XD, Liu YP, Li J, Sun J, Ou Q. Non-enzymatic glycosylation in D-galactose-induced rats aging model and the anti-aging effects of alcoholic extract of Semen Cuscutae on the aging model. Chin J Gerontol (Chin) 2009;29:2494–2495.
Wang YH, He XL, Li XX, Yang HG, Bi MG, Du GH. Protecting effect of Ginsenoside Rg1 on liver mitochondria of senescence accelerated mouse. Chin J Gerontol (Chin) 2009;29:1897–1899.
Li SJ, Zhang L, Zhang DS, Shen LX, Dong XH, Wu HX, et al. Experimental study on anti-senility effect of Chrysophanol. Chin J Gerontol (Chin) 2005;25:1362–1364.
Chen G, Zhu XF, Li DD, He QY. Anti-aging effect of Berberine on hydrogen peroxide-induced cell senescences. Conference proceedings of 1st China anti-aging and traditional Chinese medicine health; 2010:122.
Huang LY, Cui XN. Effects of Gastrodiae Elata and vitamin C on the expression of antioxidant enzymes in haloperidol-induced rat aging model. Chin J Gerontol (Chin) 2006;26:1360–1361.
Chen Q. Experimental method for anti-aging research. 1st ed. Beijing: China Medicine Science and Technology Press; 1996:16–17.
Zhang WH, Xie H. Effect of extract of poyster liquid on postponing aging of cerebra in ovariectomy rats. Chin J Gerontol (Chin) 2007; 27:1239–1241.
Ma YX, Wang ZS, Yu ZY. A further study to improve the cognitive function of the elderly. Proceedings of the 4th China geriatric medicine conference, Chinese Medical Association; 1989:111.
Zhang J, Yan CL, Zhang DS, Zhang L, Wang S, Xue GP. Mechanism and effect of gross saponins of tribulus terrestris on learning and memory of β-amyloid peptide (25–35) induced aging mouse. Chin J Gerontol (Chin) 2010; 30:3747–3749.
State Administration of Traditional Chinese Medicine of China. New Drugs of Traditional Chinese Medicine Research Guide; 1994:106–107.
Chen YR, Fang SR, Fu YC, Zhou XH, Xu MY, Xu WC. Calorie restriction on insulin resistance and expression of SIRT1 and SIRT4 in rats. Biochem Cell Biol 2010;88:715–722.
Banks R, Speakman JR, Selman C. Vitamin Esupplementation and mammalian lifespan. Mol Nutr Food Res 2010;54:719–725.
Xu FB. Subacute toxicity of D-galactgose. 2nd International symposium of aging, Harbin, China, 1985.
Zheng J. The mechanism of aging—a view from metabolism. Chin J Gerontol (Chin) 1985;2:52–55.
Xu FB, Hu XM, Zhou HH. Anti-aging effect of Gynosaponins and its compound. Chin Tradit Patent Med (Chin) 1989;11(5):29–30.
Gong GQ, Xu FB. Study of aging model in mice. J Chin Pharm Univ (Chin) 1991;22:101–103.
Shi J, Wei MJ. Advances and clinical implications of D-galactose in aging research. Chin J Gerontol (Chin) 2009;29:2001–2003.
Xing QJ, Shi Q, Wang YJ. Mechanism of establishing aging model with D-galactose and its application in research of traditional Chinese medicine. Acta Univ Tradit Med Sin Pharmacol Shanghai (Chin) 2010;24(3):93–98.
Yu ZJ, Ying DJ, Dong SW, Liu LB. Study on dosage of D-galactose inducing acute aging model. Chin J Anat (Chin) 2005;28:422–424.
Qin HB, Yang ZY, Fan YJ, Zhu Q. Establishment and evaluation of aging models induced by D-galactose in mice. J Clin Rehabil Tissue Eng Res (Chin) 2009;13:1275–1278.
Wei H, Li L, Song Q, Ai H, Chu J, Li W. Behavioural study of the D-galactose-induced aging model in C57BL/6J mice. Behav Brain Res 2005;157:245–251.
Zeng XG, Tan ZQ, Zhang H, Liu G, Wen W. A comparative study on natural aging mice and d-galactose aging mice mode. Mod Prev Med (Chin) 2001;28:416–417.
Yin T, Xu B, Zhu QL Yang J, Wang SW. Morphological difference of important viscera of mice after natural senility and aging by galactose. Chin J Clin Rehabil (Chin) 2004;8:8248–8249,8266.
Zhou QQ, Li YD. Selection of animal models of aging. Tradit Chin Med Res (Chin) 2012;26(2):48–51.
0
Views
1028
Downloads
10
CSCD
- Meta-XMLDownload
- BibTeXDownload
- EndnoteDownload
- RefMan Download
- NoteExpressDownload
- NoteFirstDownload
Publicity Resources
Related Articles
Related Author
Related Institution
- Address：1 Caochang, xiyuan, Beijing, People's Republic of China Postal code：100091
- Tel：010-62886827, 62877592 Fax：010-62874291
- Technical support is provided by Beijing Founder electronics co., LTD 京ICP备05067934号-1
京公网安备11010802024621 - It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
- Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.
