A comparison of brain activity between healthy subjects and stroke patients on fMRI by acupuncture stimulation

Seung-Yeon Cho; Mia Kim; Jong Joo Sun; Geon-Ho Jahng; Hengjun J. Kim; Seong-Uk Park; Woo-Sang Jung; Chang-Nam Ko; Jung-Mi Park

doi:10.1007/s11655-013-1436-4

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A comparison of brain activity between healthy subjects and stroke patients on fMRI by acupuncture stimulation

Updated：2021-08-27

- A comparison of brain activity between healthy subjects and stroke patients on fMRI by acupuncture stimulation
- Chinese Journal of Integrative Medicine Vol. 19, Issue 4, Pages: 269-276(2013)
- Affiliations：
  
  1. Department of Cardiology and Neurology of Korean Medicine, College of Korean Medicine, Kyung Hee University,Seoul,Korea
  2. Department of Radiology, Kyung Hee University Hospital at Gangdong, College of Medicine, Kyung Hee University,Seoul,Korea
  3. Division of Magnetic Resonance Research, Korea Basic Science Institute, Cheongwongun, Chungbuk,Korea
- Author bio：
- Funds：
- DOI：10.1007/s11655-013-1436-4
  CLC：
- Published：2013，
  
  Published Online：2 April 2013，
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Cho, SY., Kim, M., Sun, J.J. et al. A comparison of brain activity between healthy subjects and stroke patients on fMRI by acupuncture stimulation., Chin. J. Integr. Med. 19, 269–276 (2013). https://doi.org/10.1007/s11655-013-1436-4

Seung-Yeon Cho, Mia Kim, Jong Joo Sun, et al. A comparison of brain activity between healthy subjects and stroke patients on fMRI by acupuncture stimulation. [J]. Chinese Journal of Integrative Medicine 19(4):269-276(2013)
Cho, SY., Kim, M., Sun, J.J. et al. A comparison of brain activity between healthy subjects and stroke patients on fMRI by acupuncture stimulation., Chin. J. Integr. Med. 19, 269–276 (2013). https://doi.org/10.1007/s11655-013-1436-4 DOI：

Seung-Yeon Cho, Mia Kim, Jong Joo Sun, et al. A comparison of brain activity between healthy subjects and stroke patients on fMRI by acupuncture stimulation. [J]. Chinese Journal of Integrative Medicine 19(4):269-276(2013) DOI： 10.1007/s11655-013-1436-4.

摘要

To investigate brain activity patterns during acupuncture in stroke patients

and to compare the result with normal subjects using functional magnetic resonance imaging (fMRI). A total of 11 stroke patients with motor weakness and 10 healthy subjects were studied. fMRI was performed during acupuncture on the left side at points Quchi (LI11) and Zusanli (ST36). Data were analyzed using statistical parametric maps of brain activation induced by acupuncture stimulation. The results showed that stimulation of both LI11 and ST36 produced significantly different brain activation patterns between the two groups. The normal group showed a greater overall activation than the stroke group. In the normal group

parts of the frontal lobe

parietal lobe

sub-lobar

cerebellum and midbrain regions were activated by acupuncture at the left LI11. On the other hand

only the right side of the inferior parietal lobule region was activated in the stroke patients. When the left ST36 was stimulated in the normal group

both sides of the frontal lobe

parietal lobe

temporal lobe

and sub-lobar

and the left side of occipital lobe

and the right side of cerebellum and midbrain regions were activated. For the same stimulation in the stroke group

only both sides of the inferior parietal lobule and cerebellum regions were activated (P<0.05

cluster level). Deactivation pattern was not noted during any acupuncture stimulation in both groups. Brain signal activations during the same acupuncture were different between the healthy and the stroke patients

and the effects showed a correlation of different acupuncture points.

Abstract

To investigate brain activity patterns during acupuncture in stroke patients

parts of the frontal lobe

parietal lobe

sub-lobar

cerebellum and midbrain regions were activated by acupuncture at the left LI11. On the other hand

only the right side of the inferior parietal lobule region was activated in the stroke patients. When the left ST36 was stimulated in the normal group

both sides of the frontal lobe

parietal lobe

temporal lobe

and sub-lobar

and the left side of occipital lobe

and the right side of cerebellum and midbrain regions were activated. For the same stimulation in the stroke group

only both sides of the inferior parietal lobule and cerebellum regions were activated (P<0.05

and the effects showed a correlation of different acupuncture points.

关键词

acupuncturefunctional magnetic resonance imagingstrokeLI11ST36basal ganglia

Keywords

acupuncturefunctional magnetic resonance imagingstrokeLI11ST36basal ganglia

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