Effect of electrochemotherapy in treating patients with venous malformations

Jing-hong Li; Yu-ling Xin; Xue-qiang Fan; Jie Chen; Jian Wang; Jin Zhou

doi:10.1007/s11655-013-1450-6

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Effect of electrochemotherapy in treating patients with venous malformations

Updated：2021-08-27

- Effect of electrochemotherapy in treating patients with venous malformations
- Chinese Journal of Integrative Medicine Vol. 19, Issue 5, Pages: 387-393(2013)
- Affiliations：
  
  Department of Electrochemical Treatment, China-Japan Friendship Hospital,Beijing,China
- Author bio：
- Funds：
- DOI：10.1007/s11655-013-1450-6
  CLC：
- Published：2013，
  
  Published Online：15 March 2013，
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Li, Jh., Xin, Yl., Fan, Xq. et al. Effect of electrochemotherapy in treating patients with venous malformations., Chin. J. Integr. Med. 19, 387–393 (2013). https://doi.org/10.1007/s11655-013-1450-6

Jing-hong Li, Yu-ling Xin, Xue-qiang Fan, et al. Effect of electrochemotherapy in treating patients with venous malformations. [J]. Chinese Journal of Integrative Medicine 19(5):387-393(2013)
Li, Jh., Xin, Yl., Fan, Xq. et al. Effect of electrochemotherapy in treating patients with venous malformations., Chin. J. Integr. Med. 19, 387–393 (2013). https://doi.org/10.1007/s11655-013-1450-6 DOI：

Jing-hong Li, Yu-ling Xin, Xue-qiang Fan, et al. Effect of electrochemotherapy in treating patients with venous malformations. [J]. Chinese Journal of Integrative Medicine 19(5):387-393(2013) DOI： 10.1007/s11655-013-1450-6.

摘要

To evaluate the efficacy and safety of electrochemotherapy in treating venous malformations. Electrochemotherapy was applied to 665 patients with venous malformations of limbs and trunk

and 505 cases were followed up for half to 6 years. In this study

228 male and 277 female patients were involved. Diagnosis was made by clinical manifestations and magnetic resonance imaging. The platinum electrodes were inserted into tumor through a trocar with plastic insulating cannula percutaneously and connected with the electrochemical therapeutic apparatus in anodes and cathodes separately. Then electricity was given. The treating voltage is 6–12 V and volume 100–180 mA

the total electricity used is in general 80–100 coulombs per 1.0 square centimeter of tumors’ area. The treating time was usually from several dozen minutes to over 2 h depending on the size of the tumor. The severe cases which needed to be treated once again usually were operated after 6 months. The primary efficacy end point was defined as an improvement of patients’ symptoms and a reduction in size of tumor 6 months after treatment. Effects were divided into 4 grades

and the efficacy rate decreased from grade 1 to grade 4. The efficacy turned out that 30.1% (152/505) of patients was classified as grade 1; 46.3% (234/505) as grade 2; 19.0% (96/505) as grade 3 and 4.6% (23/505) as grade 4. Electrochemotherapy shows special superiorities in treating venous malformations. It might bring a confirmed clinical efficacy with the advantages of less injury

quick recovery

simple operation and less complications.

Abstract

To evaluate the efficacy and safety of electrochemotherapy in treating venous malformations. Electrochemotherapy was applied to 665 patients with venous malformations of limbs and trunk

and 505 cases were followed up for half to 6 years. In this study

quick recovery

simple operation and less complications.

关键词

venous malformationselectrochemotherapyClinical Effect

Keywords

venous malformationselectrochemotherapyClinical Effect

references

WHO handbook for reporting results of cancer treatment. Geneva, Switzerland: World Health Organization Offset Publication; 1979:23–24.

RN Hubbell, PS Ihm. Current surgical management of vascular anomalies. Curr Opin Otolaryngol Head Neck Surg 2000;8:441–447.

S Higuera, K Gordley, DW Metry, S Stal. Management of hemangiomas and pediatric vascular malformations. J Craniofacial Surg 2006;17:783–789.

F Canavese, BCL Soo, SKK Chia, JI Krajbich. Surgical outcome in patients treated for hemangioma during infancy, childhood, and adolescence: A retrospective review of 44 consecutive patients. J Pediatr Orthop 2008;28:381–386.

Mulliken JB, Fishman SJ, Burrows PE. Vascular anomalies. Curr Probl Surg 2000;37:517–584.

IT Jackson, R Carreno, Z Potparic, Hussain. Hemangiomas, vascular malformations, and lymphovenous malformations: classification and methods of treatment. Plast Reconstr Surg 1993;91:1216–1229.

Rinker B, Karp NS, Margiotta M, Blei F, Rosen R, Rofsky NM. The role of magnetic resonance imaging in the management of vascular malformations of the trunk and extremities. Plast Reconstr Surg 2003;112:504–510.

KD Hein, JB Mulliken, HPW Kozakewich, J Upton, PE Burrows, venous malformations of skeletal Muscle. Plast Reconstr Surg 2002;110:1625–1635.

Agamanolis DP, Dasu S, Krill CE Jr. Tumors of skeletal muscle. Hum Pathol 1986;17:778–795.

M Vikkula, LM Boon, JB Mulliken, BR Olsen. Molecular basis of vascular anomalies. Trends Cardiovasc Med 1998;8:281–292.

Chaudhary N, Jain A, Gudwani S, Kapoor R, Motwani G. Intramuscular haemangioma of head and neck region. J Laryngol Otol 1998;112:1199–1201.

LM Buckmiller. Update on hemangiomas and vascular malformations. Curr Opin Otolaryngol Head Neck Surg 2004;12:476–487.

Gillett D, Fahmy F, Eveson JW, Shotton JC. Intramuscular capillary hamartoma of the tongue. J Laryngol Otol 2003;117:734–735.

J Cabrera, J Cabrera Jr, MA Garcı’a-Olmedo, P Redondo. Treatment of venous malformations with sclerosant in microfoam form. Arch Dermatol 2003;139:1409–1416.

JA Stith. Current diagnostics in office practice evaluation and nonoperative management of vascular malformations. Curr Opin Otolaryngol Head Neck Surg 2000;8:448–453.

Mutaz B. The changing concept of the treatment of vascular anomalies: from fiction to facts and now to reality. J Craniofac Surg 2006;17:716–718.

GPB Bella, JC Manivel, RC Thompson Jr, DR Clohisy, EY Cheng. Intramuscular hemangioma recurrence risk Related to surgical margins. Clin Orthopaedics Related Res 2007;459:186–191.

JS Arneja, AK Gosain. An approach to the management of common vascular malformations of the trunk. J Craniofacial Surg 2006;17:761–766.

Nguyen VA, Furhapter C, Romani N, Weber F, Sepp N. Infantile hemangioma is a proliferation of β4-negative endothelial cells adjacent to HLA-DR-positive cells with dendritic cell morphology. Hum Pathol 2004;35:739–744.

JF Reinisch, RY Kim, RJ Harshbarger, and JG Meara. Surgical management of parotid hemangioma. Plast Reconstr Surg 2004;113:1940–1948.

SM Lam, EF Williams III. Vascular anomalies: review and current therapy. Curr Opin Otolaryngol Head Neck Surg 2002;10:309–315.

Xin YL, Liu DR, Meng X, Li FT, Zhang W, Zhao HC, et al. The clinical observation for electro-acupuncture on hemangioma of children. Chin Pediatr Surg (Chin) 2002;23:465–466.

Li JH, Xin YL, Zhang W. Analysis of clinical effect of electro-acupuncture on tumors of maxillofacial-oral cavity. Prac J Cancer (Chin) 2005;20:627–629.

Li JH, Xin YL, Zhang W, Liu JT, Quan KH. Effect of electroacupuncture in treating patients with Lingual Hemangioma. Chin J Integr Med 2006;12:146–149.

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Clinical Epidemiology and Internal Medicine, West China Medical College, Sichuan University

Department of Electro-chemical Therapy, China-Japan Friendship Hospital

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Hunan Medical College of TCM

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