A systematic review and meta-analysis of type 2 diabetes mellitus treatment based on the “three-typed syndrome differentiation” theory in Chinese medicine

Xiu-feng Yan; Qing Ni; Jun-ping Wei; Lan Lin

doi:10.1007/s11655-013-1462-2

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A systematic review and meta-analysis of type 2 diabetes mellitus treatment based on the “three-typed syndrome differentiation” theory in Chinese medicine

Updated：2021-08-27

- A systematic review and meta-analysis of type 2 diabetes mellitus treatment based on the “three-typed syndrome differentiation” theory in Chinese medicine
- Chinese Journal of Integrative Medicine Vol. 20, Issue 8, Pages: 633-640(2014)
- Affiliations：
  
  Guang’anmen Hospital, China Academy of Chinese Medical Sciences,Beijing,China
- Author bio：
- Funds：
- DOI：10.1007/s11655-013-1462-2
  CLC：
- Published：2014，
  
  Published Online：5 August 2013，
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Yan, Xf., Ni, Q., Wei, Jp. et al. A systematic review and meta-analysis of type 2 diabetes mellitus treatment based on the “three-typed syndrome differentiation” theory in Chinese medicine., Chin. J. Integr. Med. 20, 633–640 (2014). https://doi.org/10.1007/s11655-013-1462-2

Xiu-feng Yan, Qing Ni, Jun-ping Wei, et al. A systematic review and meta-analysis of type 2 diabetes mellitus treatment based on the “three-typed syndrome differentiation” theory in Chinese medicine. [J]. Chinese Journal of Integrative Medicine 20(8):633-640(2014)
Yan, Xf., Ni, Q., Wei, Jp. et al. A systematic review and meta-analysis of type 2 diabetes mellitus treatment based on the “three-typed syndrome differentiation” theory in Chinese medicine., Chin. J. Integr. Med. 20, 633–640 (2014). https://doi.org/10.1007/s11655-013-1462-2 DOI：

Xiu-feng Yan, Qing Ni, Jun-ping Wei, et al. A systematic review and meta-analysis of type 2 diabetes mellitus treatment based on the “three-typed syndrome differentiation” theory in Chinese medicine. [J]. Chinese Journal of Integrative Medicine 20(8):633-640(2014) DOI： 10.1007/s11655-013-1462-2.

摘要

To evaluate the efficacy and safety of “Three-Typed Syndrome Differentiation” (TTSD) in treating type 2 diabetes mellitus patients. A systematic review and meta-analysis was done based on the clinical diabetes treatment literature of the “TTSD”. Overseas databases like the PubMed/MEDLINE

EMBASE

Cochrane Library and Cochrane Central Register of Controlled Clinical Trials

and China databases like China Biology Medicine Disc (CBM)

Chinese national Knowledge Infrastructure (CNKI)

Wanfang database

and VIP database

without limitation on language

were included with the time limitation from Jan 1982 to Dec 2012 by retrieval of relative original clinical research articles. Nineteen articles where contains 1

840 diabetes patients were obtained

in which no adverse reactions were reported. Of these

14 literatures involved the effect of fasting blood glucose (FBG)

10 involved that of postprandial 2-h blood glucose (P2hBG)

and 19 involved the overall efficacy based on the national Chinese medicine (CM) diagnosis and treatment standard of diabetes. All the meta-analysis results prefer to the “TTSD” groups (CM+Western medicine Based on TTSD). The results show that

beside the efficacy of Western medicine

the concentrations of FBG and P2hBG in “TTSD” groups continue to drop with statistical significance. For “TTSD” groups

the FBG subsequently dropped 1.03 mmol/L

95%CI [1.24

0.82] P <0.00001)

the P2hBG subsequently dropped 1.09 mmol/L

95% CI [1.61

0.57] (P <0.0001)

and the overall efficacies benefit 3.46 times those of Western medicine alone

95% CI [2.67

4.48] (P <0.00001). The CM by the diagnosis and treatment of type 2 diabetes based on TTSD might be safe and effective

and could better improve both blood glucose and the overall status of patients

including symptoms.

Abstract

EMBASE

Cochrane Library and Cochrane Central Register of Controlled Clinical Trials

and China databases like China Biology Medicine Disc (CBM)

Chinese national Knowledge Infrastructure (CNKI)

Wanfang database

and VIP database

without limitation on language

were included with the time limitation from Jan 1982 to Dec 2012 by retrieval of relative original clinical research articles. Nineteen articles where contains 1

840 diabetes patients were obtained

in which no adverse reactions were reported. Of these

14 literatures involved the effect of fasting blood glucose (FBG)

10 involved that of postprandial 2-h blood glucose (P2hBG)

beside the efficacy of Western medicine

the concentrations of FBG and P2hBG in “TTSD” groups continue to drop with statistical significance. For “TTSD” groups

the FBG subsequently dropped 1.03 mmol/L

95%CI [1.24

0.82] P <0.00001)

the P2hBG subsequently dropped 1.09 mmol/L

95% CI [1.61

0.57] (P <0.0001)

and the overall efficacies benefit 3.46 times those of Western medicine alone

95% CI [2.67

4.48] (P <0.00001). The CM by the diagnosis and treatment of type 2 diabetes based on TTSD might be safe and effective

and could better improve both blood glucose and the overall status of patients

including symptoms.

关键词

three-typed syndrome differentiationtype 2 diabetes mellitusChinese Medicinesystematic reviewmeta-analysis

Keywords

three-typed syndrome differentiationtype 2 diabetes mellitusChinese Medicinesystematic reviewmeta-analysis

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