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Correlation between different Chinese medicine syndromes and changes in microcirculation in septic shock patients
- Chinese Journal of Integrative Medicine Vol. 19, Issue 10, Pages: 730-735(2013)
- Affiliations：
Department of Critical Care Medicine, Beijing Friendship Hospital Affiliated to Capital Medical University,Beijing,China
- Author bio：
- Funds：Supported by the Fund of Medicine Development in Beijing (No. SF-2009-II-14)
DOI：10.1007/s11655-013-1592-6
CLC：Published：2013，
Published Online：23 August 2013，
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Liu, Jf., Zhao, My., Zhuang, Hz. et al. Correlation between different Chinese medicine syndromes and changes in microcirculation in septic shock patients., Chin. J. Integr. Med. 19, 730–735 (2013). https://doi.org/10.1007/s11655-013-1592-6
Jing-feng Liu, Meng-ya Zhao, Hai-zhou Zhuang, et al. Correlation between different Chinese medicine syndromes and changes in microcirculation in septic shock patients. [J]. Chinese Journal of Integrative Medicine 19(10):730-735(2013)
Liu, Jf., Zhao, My., Zhuang, Hz. et al. Correlation between different Chinese medicine syndromes and changes in microcirculation in septic shock patients., Chin. J. Integr. Med. 19, 730–735 (2013). https://doi.org/10.1007/s11655-013-1592-6 DOI：
Jing-feng Liu, Meng-ya Zhao, Hai-zhou Zhuang, et al. Correlation between different Chinese medicine syndromes and changes in microcirculation in septic shock patients. [J]. Chinese Journal of Integrative Medicine 19(10):730-735(2013) DOI： 10.1007/s11655-013-1592-6.
摘要
To investigate the correlation between different Chinese medicine (CM) syndromes and variations in microcirculation in septic shock patients. seventy Septic shock patients were divided into four groups: heat damaging qi-yin group (HDQY
23 cases); yin exhaustion and yang collapse group (YEYC
26 cases); excessive heat in Fu organ group (EHFO
10 cases); and heat damaging nutrient-blood group (HDNB
11 cases). Sublingual microcirculation parameters were observed by sidestream dark-field (SDF) imaging and scored by Acute Physiology and Chronic Health Evaluation II (APACHE II) and the Sequential Organ Failure Assessment (SOFA)
and parameters of microcirculation perfusion variations and prognoses were analyzed. Compared with those with qi-yin heat damage
perfused vessel density (PVD) in other groups decreased dramatically (P<0.05)
and APACHE II scores increased significantly (P<0.05). In addition
the recovery time was prolonged substantially (P<0.05)
and the mixed venous oxygen saturation (SVO2) decreased (P<0.05). Blood lactic acid increased significantly (P<0.05)
and the mixed SVO decreased (P<0.05)
in the YEYC group. Compared with the thermal injury camp blood group
sublingual microcirculation parameter variations showed no obvious difference in the YEYC and EHFO groups (P>0.05). There were significant positive correlations between CM syndromes and APACHE II scoring in different groups (r=0.512
P<0.05). There were negative correlations between PVD and APACHE II scoring (r=−0.378
P=0.043)
the proportion of perfused vessels (PPV) and APACHE II scoring (r=−0.472
P=0.008)
as well as between the microvascular flow index (MFI) and APACHE II scoring (r=−0.424
P=0.023) in different patients. Sublingual microcirculation may serve as a clinical diagnostic parameter of the patient condition
as well as being a prognostic indicator.
Abstract
To investigate the correlation between different Chinese medicine (CM) syndromes and variations in microcirculation in septic shock patients. seventy Septic shock patients were divided into four groups: heat damaging qi-yin group (HDQY
23 cases); yin exhaustion and yang collapse group (YEYC
26 cases); excessive heat in Fu organ group (EHFO
10 cases); and heat damaging nutrient-blood group (HDNB
11 cases). Sublingual microcirculation parameters were observed by sidestream dark-field (SDF) imaging and scored by Acute Physiology and Chronic Health Evaluation II (APACHE II) and the Sequential Organ Failure Assessment (SOFA)
and parameters of microcirculation perfusion variations and prognoses were analyzed. Compared with those with qi-yin heat damage
perfused vessel density (PVD) in other groups decreased dramatically (P<0.05)
and APACHE II scores increased significantly (P<0.05). In addition
the recovery time was prolonged substantially (P<0.05)
and the mixed venous oxygen saturation (SVO2) decreased (P<0.05). Blood lactic acid increased significantly (P<0.05)
and the mixed SVO decreased (P<0.05)
in the YEYC group. Compared with the thermal injury camp blood group
sublingual microcirculation parameter variations showed no obvious difference in the YEYC and EHFO groups (P>0.05). There were significant positive correlations between CM syndromes and APACHE II scoring in different groups (r=0.512
P<0.05). There were negative correlations between PVD and APACHE II scoring (r=−0.378
P=0.043)
the proportion of perfused vessels (PPV) and APACHE II scoring (r=−0.472
P=0.008)
as well as between the microvascular flow index (MFI) and APACHE II scoring (r=−0.424
P=0.023) in different patients. Sublingual microcirculation may serve as a clinical diagnostic parameter of the patient condition
as well as being a prognostic indicator.
关键词
septic shocksublingual microcirculationChinese medicine syndromes
Keywords
septic shocksublingual microcirculationChinese medicine syndromes
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