Nodule and eminence on frenulum labii superioris: Diagnostic markers for metastatic colorectal cancer

Rui Cao; Li-ping Wang; Jia-dong Chi; Xiong-zhi Wu

doi:10.1007/s11655-014-1681-1

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Nodule and eminence on frenulum labii superioris: Diagnostic markers for metastatic colorectal cancer

Updated：2021-08-27

- Nodule and eminence on frenulum labii superioris: Diagnostic markers for metastatic colorectal cancer
- Chinese Journal of Integrative Medicine Vol. 20, Issue 6, Pages: 416-419(2014)
- Affiliations：
  
  1. National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin Medical University Cancer Institute and Hospital,Tianjin,China
  2. Tianjin Medical University,Tianjin,China
- Author bio：
- Funds：
  
  Supported by the National Natural Science Foundation of China (No. 81173376) and New Century Excellent Talent (NCET-11-1068)
- DOI：10.1007/s11655-014-1681-1
  CLC：
- Published：2014，
  
  Published Online：21 June 2014，
Scan for full text
Cao, R., Wang, Lp., Chi, Jd. et al. Nodule and eminence on frenulum labii superioris: Diagnostic markers for metastatic colorectal cancer., Chin. J. Integr. Med. 20, 416–419 (2014). https://doi.org/10.1007/s11655-014-1681-1

Rui Cao, Li-ping Wang, Jia-dong Chi, et al. Nodule and eminence on frenulum labii superioris: Diagnostic markers for metastatic colorectal cancer. [J]. Chinese Journal of Integrative Medicine 20(6):416-419(2014)
Cao, R., Wang, Lp., Chi, Jd. et al. Nodule and eminence on frenulum labii superioris: Diagnostic markers for metastatic colorectal cancer., Chin. J. Integr. Med. 20, 416–419 (2014). https://doi.org/10.1007/s11655-014-1681-1 DOI：

Rui Cao, Li-ping Wang, Jia-dong Chi, et al. Nodule and eminence on frenulum labii superioris: Diagnostic markers for metastatic colorectal cancer. [J]. Chinese Journal of Integrative Medicine 20(6):416-419(2014) DOI： 10.1007/s11655-014-1681-1.

摘要

To determine whether the nodule and eminence on the frenulum labii superioris

location of Yinjiao (DU28) according to the meridian theory

could be used to prognosticate the recurrence of patients with colorectal cancer. The data of 101 patients with colorectal cancer in Tianjin Medical University Cancer Institute and Hospital from May 2011 to November 2011 was analyzed. The photos of all patients’ frenulum labii superioris were taken. Nodule and eminence on frenulum labii superioris were the positive standard. Biopsy and pathological testing for the nodule were carried out on one patient with large nodule on frenulum labii superioris. Patients with positive frenulum labii superioris had a higher risk of recurrence and/or metastasis than patients with negative frenulum labii superioris. There were no significant differences in diagnosis of recurrence and/or metastasis between the status of frenulum labii superioris and the traditional diagnostic criteria (P =0.238). The Kappa was 0.606 (P <0.001). The sensitivity was 76.0% and the specificity was 85.4%. The pathological report demonstrated that the nodule on frenulum labii superioris was mucosal excrescence with normal structure. Nodule and eminence on frenulum labii superioris are potential diagnostic markers for metastatic colorectal cancer.

Abstract

To determine whether the nodule and eminence on the frenulum labii superioris

location of Yinjiao (DU28) according to the meridian theory

关键词

colorectal cancermetastasisrecurrencefrenulum labii superioris

Keywords

colorectal cancermetastasisrecurrencefrenulum labii superioris

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Related Institution

Department of Traditional Chinese Medicine, Changhai Hospital, Second Military Medical University

National Clinical Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin Medical University Cancer Institute and Hospital

Department of Medical Oncology, Tianjin Medical Universty General Hospital

Zhong-Shan-Men In-patient Department, Tianjin Medical University Cancer Institute and Hospital

Department of Chemistry, University of South Florida

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