Songling Xuemaikang Capsule (松龄血脉康胶囊) for primary hypertension: A systematic review of randomized controlled trials

Xiao-chen Yang; Xing-jiang Xiong; Guo-yan Yang; He-ran Wang; Jie Wang

doi:10.1007/s11655-014-1709-6

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Songling Xuemaikang Capsule (松龄血脉康胶囊) for primary hypertension: A systematic review of randomized controlled trials

Updated：2021-08-27

- Songling Xuemaikang Capsule (松龄血脉康胶囊) for primary hypertension: A systematic review of randomized controlled trials
- Chinese Journal of Integrative Medicine Vol. 21, Issue 4, Pages: 312-320(2015)
- Affiliations：
  
  1. Department of Cardiology, Guang’anmen Hospital, China Academy of Chinese Medical Sciences,Beijing,China
  2. Centre for Evidence-Based Chinese Medicine, Beijing University of Chinese Medicine,Beijing,China
  3. Cancer Research Institute, Central South University,Changsha,China
- Author bio：
- Funds：
- DOI：10.1007/s11655-014-1709-6
  CLC：
- Published：2015，
  
  Published Online：2 March 2014，
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Yang, Xc., Xiong, Xj., Yang, Gy. et al. Songling Xuemaikang Capsule (松龄血脉康胶囊) for primary hypertension: A systematic review of randomized controlled trials., Chin. J. Integr. Med. 21, 312–320 (2015). https://doi.org/10.1007/s11655-014-1709-6

Xiao-chen Yang, Xing-jiang Xiong, Guo-yan Yang, et al. Songling Xuemaikang Capsule (松龄血脉康胶囊) for primary hypertension: A systematic review of randomized controlled trials. [J]. Chinese Journal of Integrative Medicine 21(4):312-320(2015)
Yang, Xc., Xiong, Xj., Yang, Gy. et al. Songling Xuemaikang Capsule (松龄血脉康胶囊) for primary hypertension: A systematic review of randomized controlled trials., Chin. J. Integr. Med. 21, 312–320 (2015). https://doi.org/10.1007/s11655-014-1709-6 DOI：

Xiao-chen Yang, Xing-jiang Xiong, Guo-yan Yang, et al. Songling Xuemaikang Capsule (松龄血脉康胶囊) for primary hypertension: A systematic review of randomized controlled trials. [J]. Chinese Journal of Integrative Medicine 21(4):312-320(2015) DOI： 10.1007/s11655-014-1709-6.

摘要

To evaluate the effectiveness and safety of Songling Xuemaikang Capsule (松龄血脉康胶囊

SXC) for the treatment of primary hypertension. An extensive search including Cochrane Library

PubMed

Cochrane Central Register of Controlled Trials (CENTRAL)

Chinese Biomedical Literature Database (CBM)

Chinese National Knowledge Infrastructure (CNKI)

Chinese Scientific Journal Database (VIP)

KoreaMed

Japanese database

and online clinical trial registry websites was performed up to February 2013. Randomized controlled trials (RCTs) regarding SXC for the treatment of primary hypertension were searched without no language restrictions. The quality of each trial was assessed according to the Cochrane Reviewers’ Handbook 5.0

and RevMan 5.0 provided by the Cochrane Collaboration. A total of 17 RCTs involving 1

778 patients were included. Meta-analysis showed that there was no significant difference between SXC and antihypertensive agents on systolic blood pressure [mean difference (MD): −0.10 [−4.83

4.63]; P=0.97] and diastolic blood pressure (MD: 1.00 [−1.16

3.16]; P=0.36)

but SXC combined with antihypertensive drugs was more effective in lowering systolic blood pressure (MD: −6.17 [−7.86

−4.49]; P<0.00001) and diastolic blood pressure (MD: −7.24 [−8.62

−5.85]; P<0.00001) compared with the antihypertensive drugs alone. SXC used alone or combined with antihypertensive drugs appear to be an effective treatment for lowering elevated blood pressure and improving symptoms in patients with primary hypertension. However

the conclusion cannot be drawn definitely due to the poor quality of the included studies. There is still an urgent need for well-designed

long-term studies to address the benefits of SXC for treating primary hypertension.

Abstract

To evaluate the effectiveness and safety of Songling Xuemaikang Capsule (松龄血脉康胶囊

SXC) for the treatment of primary hypertension. An extensive search including Cochrane Library

PubMed

Cochrane Central Register of Controlled Trials (CENTRAL)

Chinese Biomedical Literature Database (CBM)

Chinese National Knowledge Infrastructure (CNKI)

Chinese Scientific Journal Database (VIP)

KoreaMed

Japanese database

and RevMan 5.0 provided by the Cochrane Collaboration. A total of 17 RCTs involving 1

778 patients were included. Meta-analysis showed that there was no significant difference between SXC and antihypertensive agents on systolic blood pressure [mean difference (MD): −0.10 [−4.83

4.63]; P=0.97] and diastolic blood pressure (MD: 1.00 [−1.16

3.16]; P=0.36)

but SXC combined with antihypertensive drugs was more effective in lowering systolic blood pressure (MD: −6.17 [−7.86

−4.49]; P<0.00001) and diastolic blood pressure (MD: −7.24 [−8.62

the conclusion cannot be drawn definitely due to the poor quality of the included studies. There is still an urgent need for well-designed

long-term studies to address the benefits of SXC for treating primary hypertension.

关键词

Songling Xuemaikang Capsuleprimary hypertensionChinese Patent Medicinesystematic reviewrandomized controlled trials

Keywords

Songling Xuemaikang Capsuleprimary hypertensionChinese Patent Medicinesystematic reviewrandomized controlled trials

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