Analysis of clinical evaluation of response to treatment of Parkinson’s disease with integrated Chinese and Western medicine therapy

Min Li; Ming-hui Yang; Yi Liu; Xiao-dong Luo; Jian-zong Chen; Heng-jun Shi

doi:10.1007/s11655-014-1760-3

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Analysis of clinical evaluation of response to treatment of Parkinson’s disease with integrated Chinese and Western medicine therapy

Updated：2021-08-27

- Analysis of clinical evaluation of response to treatment of Parkinson’s disease with integrated Chinese and Western medicine therapy
- Chinese Journal of Integrative Medicine Vol. 21, Issue 1, Pages: 17-21(2015)
- Affiliations：
  
  1. Institute of Chinese Medicine, the General Hospital of the People’s Liberation Army,Beijing,China
  2. Department of Internal Medicine, Guangdong Provincial Hospital of Traditional Chinese Medicine,Guangzhou,China
  3. Department of Chinese Medicine, Xijing Hospital, the Fourth Military Medical University,Xi’an,China
- Author bio：
- Funds：
  
  Supported by the National Ministry of Science and Technology “Eleventh Five-Year” Project of China (No. 2006BAI04A11)
- DOI：10.1007/s11655-014-1760-3
  CLC：
- Published：2015，
  
  Published Online：10 June 2014，
Scan for full text
Li, M., Yang, Mh., Liu, Y. et al. Analysis of clinical evaluation of response to treatment of Parkinson’s disease with integrated Chinese and Western medicine therapy., Chin. J. Integr. Med. 21, 17–21 (2015). https://doi.org/10.1007/s11655-014-1760-3

Min Li, Ming-hui Yang, Yi Liu, et al. Analysis of clinical evaluation of response to treatment of Parkinson’s disease with integrated Chinese and Western medicine therapy. [J]. Chinese Journal of Integrative Medicine 21(1):17-21(2015)
Li, M., Yang, Mh., Liu, Y. et al. Analysis of clinical evaluation of response to treatment of Parkinson’s disease with integrated Chinese and Western medicine therapy., Chin. J. Integr. Med. 21, 17–21 (2015). https://doi.org/10.1007/s11655-014-1760-3 DOI：

Min Li, Ming-hui Yang, Yi Liu, et al. Analysis of clinical evaluation of response to treatment of Parkinson’s disease with integrated Chinese and Western medicine therapy. [J]. Chinese Journal of Integrative Medicine 21(1):17-21(2015) DOI： 10.1007/s11655-014-1760-3.

摘要

To analyze the clinical evaluation of Parkinson’s disease (PD) patients receiving integrated Chinese and Western medicine therapy. One hundred and twenty patients were enrolled and randomly allocated to a control group or treatment group. Patients in the two groups received placebo and Bushen Huoxue Granule (补肾活血颗粒

BHG)

respectively. Both groups received baseline levodopa and benserazide (Madopar). The effects of treatment were assessed monthly during the 9-month treatment. Means of evaluation included Unified PD Rating Scale (UPDRS) scores (II and III)

sleep scale score

10 m turn back test (getting up time

10 m×2 times

and turning time)

timing motor test (TMT)-left and TMT-right

which were treated as the dependent variables; and age

sex

duration of PD

Hoehn and Yahr (H-Y) stage and Madopar dosage of admitted PD patients were as the independent variables. Multiple linear regression was used to analyze these factors. H-Y stage significantly affected UPDRS II score

UPDRS III score

and getting up time (P<0.01). Madopar dosage and H-Y stage significantly affected the 10 m×2 times (P<0.05 or <0.01). Madopar dosage significantly affected the sleep scale score (P<0.05). There were also significant correlations between age and TMT-left or TMT-right (P<0.01)

and duration of PD and TMT-right (P<0.05). The six assessed means of clinical evaluation (including UPDRS II and UPDRS III scores

sleep scale score

getting up time

10 m×2 times

and turning time) are sensitive indexes in all PD patients. H-Y stage and Madopar dosage are the major factors influencing means of clinical assessment of PD treatment.

Abstract

BHG)

sleep scale score

10 m turn back test (getting up time

10 m×2 times

and turning time)

timing motor test (TMT)-left and TMT-right

which were treated as the dependent variables; and age

sex

duration of PD

UPDRS III score

and duration of PD and TMT-right (P<0.05). The six assessed means of clinical evaluation (including UPDRS II and UPDRS III scores

sleep scale score

getting up time

10 m×2 times

and turning time) are sensitive indexes in all PD patients. H-Y stage and Madopar dosage are the major factors influencing means of clinical assessment of PD treatment.

关键词

Parkinson’s diseaseintegrated Chinese and Western medicine therapymeans of clinical evaluation

Keywords

Parkinson’s diseaseintegrated Chinese and Western medicine therapymeans of clinical evaluation

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