Astragalus membranaceus Injection combined with conventional treatment for viral myocarditis: A systematic review of randomized controlled trials

Yuan-lin Piao; Xiao-chun Liang

doi:10.1007/s11655-014-1825-3

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Astragalus membranaceus Injection combined with conventional treatment for viral myocarditis: A systematic review of randomized controlled trials

Updated：2021-08-27

- Astragalus membranaceus Injection combined with conventional treatment for viral myocarditis: A systematic review of randomized controlled trials
- Chinese Journal of Integrative Medicine Vol. 20, Issue 10, Pages: 787-791(2014)
- Affiliations：
  
  Department of Traditional Chinese Medicine, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences,Beijing,China
- Author bio：
- Funds：
  
  Supported by the Health Industry Scientific Research Special Funding Subproject (No. 200902008-04)
- DOI：10.1007/s11655-014-1825-3
  CLC：
- Published：2014，
  
  Published Online：6 August 2014，
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Piao, Yl., Liang, Xc. , Astragalus membranaceus Injection combined with conventional treatment for viral myocarditis: A systematic review of randomized controlled trials., Chin. J. Integr. Med. 20, 787–791 (2014). https://doi.org/10.1007/s11655-014-1825-3

Yuan-lin Piao, Xiao-chun Liang. Astragalus membranaceus Injection combined with conventional treatment for viral myocarditis: A systematic review of randomized controlled trials. [J]. Chinese Journal of Integrative Medicine 20(10):787-791(2014)
Piao, Yl., Liang, Xc. , Astragalus membranaceus Injection combined with conventional treatment for viral myocarditis: A systematic review of randomized controlled trials., Chin. J. Integr. Med. 20, 787–791 (2014). https://doi.org/10.1007/s11655-014-1825-3 DOI：

Yuan-lin Piao, Xiao-chun Liang. Astragalus membranaceus Injection combined with conventional treatment for viral myocarditis: A systematic review of randomized controlled trials. [J]. Chinese Journal of Integrative Medicine 20(10):787-791(2014) DOI： 10.1007/s11655-014-1825-3.

摘要

To assess the efficacy and safety of Astragalus membranaceus Injection combined with conventional therapy in the treatment of viral myocarditis. Randomized controlled trials (RCTs) of A. membranaceus Injection combined with conventional treatment compared with conventional treatment alone were included. Study population characteristics and outcome results were extracted independently by two assessors. Meta-analysis was performed for data available. Six RCTs

involving 639 participants

were included in this study. The methodological quality of the included trials was generally low

and there was high risk of publication bias in the included trials. The total effective rate of A. membranaceus Injection combined with conventional treatment was significantly higher than that of conventional treatment alone. Compared with conventional treatment

the cointervention treatment group showed significant recovery in myocardium enzyme levels and electrocardiography. Two RCTs reported there were no adverse effects from A. membranaceus Injection combined with conventional treatment. A. membranaceus Injection combined with conventional treatment appeared to be more efficacious compared with conventional treatment alone for treating viral myocarditis. However

this conclusion should be cautiously interpreted due to low methodological quality

small sample size

limited number of trials

and high risk of publication bias and other unidentified risks of bias. The safety of A. membranaceus Injection combined with conventional treatment remains uncertain.

Abstract

involving 639 participants

were included in this study. The methodological quality of the included trials was generally low

this conclusion should be cautiously interpreted due to low methodological quality

small sample size

limited number of trials

and high risk of publication bias and other unidentified risks of bias. The safety of A. membranaceus Injection combined with conventional treatment remains uncertain.

关键词

Viral MyocarditisAstragalus membranaceus Injectionsystematic reviewrandomized controlled trialChinese Medicine

Keywords

Viral MyocarditisAstragalus membranaceus Injectionsystematic reviewrandomized controlled trialChinese Medicine

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The First Hospital of Beijing University of Chinese Medicine

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