Effect of Zhubin (KI9) acupuncture in reducing alcohol craving in patients with alcohol dependence: A randomized placebo-controlled trial

Jin-Seong Lee; Sung-Gon Kim; Taek-Geun Jung; Woo Young Jung; Seong-Yeon Kim

doi:10.1007/s11655-014-1851-1

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Effect of Zhubin (KI9) acupuncture in reducing alcohol craving in patients with alcohol dependence: A randomized placebo-controlled trial

Updated：2021-08-27

- Effect of Zhubin (KI9) acupuncture in reducing alcohol craving in patients with alcohol dependence: A randomized placebo-controlled trial
- Chinese Journal of Integrative Medicine Vol. 21, Issue 4, Pages: 307-311(2015)
- Affiliations：
  
  1. Department of Psychiatry, Pusan National University Yangsan Hospital, Yangsan, Gyeongnam, South Korea
  2. Biomedical Research Institute, Pusan National University Hospital, Pusan, South Korea
  3. Jang-Cheon Korean Medicine Clinic, Pusan, South Korea
  4. Division of Management Information Science (S-YK), Dong-A University, Pusan, South Korea
- Author bio：
- Funds：
  
  Supported by Medical Research Institute Grant (No. 2008-03), Pusan National University, Korea
- DOI：10.1007/s11655-014-1851-1
  CLC：
- Published：2015，
  
  Published Online：24 September 2014，
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Lee, JS., Kim, SG., Jung, TG. et al. Effect of Zhubin (KI9) acupuncture in reducing alcohol craving in patients with alcohol dependence: A randomized placebo-controlled trial., Chin. J. Integr. Med. 21, 307–311 (2015). https://doi.org/10.1007/s11655-014-1851-1

Jin-Seong Lee, Sung-Gon Kim, Taek-Geun Jung, et al. Effect of Zhubin (KI9) acupuncture in reducing alcohol craving in patients with alcohol dependence: A randomized placebo-controlled trial. [J]. Chinese Journal of Integrative Medicine 21(4):307-311(2015)
Lee, JS., Kim, SG., Jung, TG. et al. Effect of Zhubin (KI9) acupuncture in reducing alcohol craving in patients with alcohol dependence: A randomized placebo-controlled trial., Chin. J. Integr. Med. 21, 307–311 (2015). https://doi.org/10.1007/s11655-014-1851-1 DOI：

Jin-Seong Lee, Sung-Gon Kim, Taek-Geun Jung, et al. Effect of Zhubin (KI9) acupuncture in reducing alcohol craving in patients with alcohol dependence: A randomized placebo-controlled trial. [J]. Chinese Journal of Integrative Medicine 21(4):307-311(2015) DOI： 10.1007/s11655-014-1851-1.

摘要

To examine the effect of acupuncture on Zhubin (KI9) in reducing alcohol craving in alcohol-dependent patients. Twenty male alcohol-dependent patients were randomly assigned to two groups

a treatment group (10 cases

age 43.0±6.8 years) and a placebo group (10 cases

age 44.5±7.9 years). The treatment group was treated with real needle acupuncture on Zhubin (KI9) twice a week for 4 weeks

and the control group was treated with placebo needle acupuncture. Both groups were given acupuncture treatment using Park Sham Device (PSD). Alcohol craving was measured by the Visual Analogue Scale (VAS) before treatment to establish a baseline

and after 1

and 4 weeks of treatment. Repeated measures ANOVA was used to determine the main and interaction effects of time and on the outcome measure (VAS). There was a significant effect of time on VAS score (df=3

F=13.3

P<0.01). Main effect of group on VAS score was significant (df=1

F=10.9

P<0.01) and the time×group interaction was also significant (df=3

F=4.7

P<0.01). Real-needle acupuncture therapy on Zhubin (KI9) showed effectiveness in reducing alcohol craving. These results strongly suggest the usefulness of acupuncture therapy on Zhubin (KI9) in preventing a relapse in alcohol dependent patients.

Abstract

To examine the effect of acupuncture on Zhubin (KI9) in reducing alcohol craving in alcohol-dependent patients. Twenty male alcohol-dependent patients were randomly assigned to two groups

a treatment group (10 cases

age 43.0±6.8 years) and a placebo group (10 cases

age 44.5±7.9 years). The treatment group was treated with real needle acupuncture on Zhubin (KI9) twice a week for 4 weeks

and after 1

F=13.3

P<0.01). Main effect of group on VAS score was significant (df=1

F=10.9

P<0.01) and the time×group interaction was also significant (df=3

F=4.7

关键词

alcohol cravingalcohol dependenceacupunctureZhubin (KI9)

Keywords

alcohol cravingalcohol dependenceacupunctureZhubin (KI9)

references

Franck J, Jayaram-Lindstrom N. Pharmacotherapy for alcohol dependence: status of current treatments. Current Opin Neurobiol 2013;23:692–699.

Schneekloth TD, Biernacka JM, Hall-Flavin DK, Karpyak VM, Frye MA, Loukianova LL, et al. Alcohol craving as a predictor of relapse. Am J Addict 2012;21(Suppl 1):S20–S26.

Shwartz M, Saitz R, Mulvey K, Brannigan P. The value of acupuncture detoxification programs in a substance abuse treatment system. J Subst Abuse Treat 1999;17:305–312.

Karst M, Passie T, Friedrich S, Wiese B, Schneider U. Acupuncture in the treatment of alcohol withdrawal symptoms: a randomized, placebo-controlled inpatient study. Addict Biol 2002;7:415–419.

Bullock ML, Culliton PD, Olander RT. Controlled trial of acupuncture for severe recidivist alcoholism. Lancet 1989;1:1435–1439.

Bullock ML, Umen AJ, Culliton PD, Olander RT. Acupuncture treatment of alcoholic recidivism: a pilot study. Alcohol Clin Exp Res 1987;11:292–295.

Sapir-Weise R, Berglund M, Frank A, Kristenson H. Acupuncture in alcoholism treatment: a randomized outpatient study. Alcohol Alcoholism 1999;34:629–635.

Worner TM, Zeller B, Schwarz H, Zwas F, Lyon D. Acupuncture fails to improve treatment outcome in alcoholics. Drug Alcohol Depend 1992;30:169–173.

Bullock ML, Kiresuk TJ, Sherman RE, Lenz SK, Culliton PD, Boucher TA, et al. A large randomized placebo controlled study of auricular acupuncture for alcohol dependence. J Subst Abuse Treat 2002;22(2):71–77.

Lee KM, Lee SY, Kim SW, Ha ID, Cho GH, Park HJ, et al. Is it possible to apply placebo auricular acupuncture to Korean?—The effects of placebo auricular acupuncture through single-blind method and randomized controlled tiral. J Kor Acup Moxibust Soc 2003;20:145–160.

Margolin A, Chang P, Avants SK, Kosten TR. Effects of sham and real auricular needling: implications for trilas of acupuncture for cocaine addiction. Am J Chin Med 1993;21:103–111.

Chiu Ml, Li LY. Chinese acupuncture and moxibustion. Edinburgh, New York: Churchill Livingstone; 1993.

Liu G. A complement work of present acupuncture and moxibustion. Techniques of acupuncture and moxibustion. 1st ed. Beijing: Huaxia Publishing House; 1998.

American Psychiatric Association, American Psychiatric Association. Task Force on DSM-IV. Diagnostic and statistical manual of mental disorders: DSM-IV-TR. 4th ed. Washington, DC: American Psychiatric Association; 2000.

Park JB, White A, Stevinson C, Ernst E, James M. Validating a new non-penetrating sham acupuncture device: two randomized controlled trials. Acupunct Med 2002;20:168–174.

Brewington V, Smith M, Lipton D. Acupuncture as a detoxification treatment: an analysis of controlled research. J Subst Abuse Treat 1994;11:289–307.

Park J, White A, Lee H, Ernst E. Development of a new sham needle. Acupunct Med 1999;17:110–112.

Xu M, Lee DT, Xie JH, Dai WJ, Chen L, Deng B, et al. A database on treating drug addiction with traditional Chinese medicine. Addiction 2007;102:282–288.

Blum K, Sheridan PJ, Wood RC, Braverman ER, Chen JJ, Cull JG, et al. The D2 dopamine receptor gene as a determinant of reward deficiency syndrome. J R Soc Med 1996;89:396–400.

D’Alberto A. Auricular acupuncture in the treatment of cocaine/crack abuse: a review of the efficacy, the use of the National Acupuncture Detoxification Association protocol, and the selection of sham points. J Altern Complement Med 2004;10:985–1000.

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Acupuncture and Moxibustion Department, Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University

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Department of Traditional Chinese Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences

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