Acupuncture treatment modulates the resting-state functional connectivity of brain regions in migraine patients without aura

Yong Zhang; Kuang-shi Li; Hong-wei Liu; Cai-hong Fu; Sheng Chen; Zhong-jian Tan; Yi Ren

doi:10.1007/s11655-015-2042-4

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Acupuncture treatment modulates the resting-state functional connectivity of brain regions in migraine patients without aura

Updated：2021-08-27

- Acupuncture treatment modulates the resting-state functional connectivity of brain regions in migraine patients without aura
- Chinese Journal of Integrative Medicine Vol. 22, Issue 4, Pages: 293-301(2016)
- Affiliations：
  
  1. Department of Neurology and Stroke Center, Dongzhimen Hospital, the First Affiliated Hospital of Beijing University of Chinese Medicine,Beijing,China
  2. Department of Acupuncture, Dongzhimen Hospital, the First Affiliated Hospital of Beijing University of Chinese Medicine,Beijing,China
  3. Department of Magnetic Resonance Imaging, Dongzhimen Hospital, the First Affiliated Hospital of Beijing University of Chinese Medicine,Beijing,China
- Author bio：
- Funds：
  
  Supported by the National Natural Science Foundation of China (No. 81473667), Beijing Young Talent Program of Beijing Education Committee (No. YETP0823), and the Research Funds of Beijing University of Chinese Medicine (No. 2013-JYBZZJS-148, 2014-JYBZZ-XS-142)
- DOI：10.1007/s11655-015-2042-4
  CLC：
- Published：2016，
  
  Published Online：6 April 2015，
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Zhang, Y., Li, Ks., Liu, Hw. et al. Acupuncture treatment modulates the resting-state functional connectivity of brain regions in migraine patients without aura., Chin. J. Integr. Med. 22, 293–301 (2016). https://doi.org/10.1007/s11655-015-2042-4

Yong Zhang, Kuang-shi Li, Hong-wei Liu, et al. Acupuncture treatment modulates the resting-state functional connectivity of brain regions in migraine patients without aura. [J]. Chinese Journal of Integrative Medicine 22(4):293-301(2016)
Zhang, Y., Li, Ks., Liu, Hw. et al. Acupuncture treatment modulates the resting-state functional connectivity of brain regions in migraine patients without aura., Chin. J. Integr. Med. 22, 293–301 (2016). https://doi.org/10.1007/s11655-015-2042-4 DOI：

Yong Zhang, Kuang-shi Li, Hong-wei Liu, et al. Acupuncture treatment modulates the resting-state functional connectivity of brain regions in migraine patients without aura. [J]. Chinese Journal of Integrative Medicine 22(4):293-301(2016) DOI： 10.1007/s11655-015-2042-4.

摘要

To investigate the modulatory effect of acupuncture treatment on the resting-state functional connectivity of brain regions in migraine without aura (MWoA) patients. Twelve MWoA patients were treated with standard acupuncture treatment for 4 weeks. All MWoA patients received resting-state functional magnetic resonance imaging (fMRI) scanning before and after acupuncture treatment. Another 12 normal subjects matched in age and gender were recruited to serve as healthy controls. The changes of restingstate functional connectivity in MWoA patients before and after the acupuncture treatment and those with the healthy controls were compared. Before acupuncture treatment

the MWoA patients had significantly decreased functional connectivity in certain brain regions within the frontal and temporal lobe when compared with the healthy controls. After acupuncture treatment

brain regions showing decreased functional connectivity revealed significant reduction in MWoA patients compared with before acupuncture treatment. Acupuncture treatment could increase the functional connectivity of brain regions in the intrinsic decreased brain networks in MWoA patients. The results provided further insights into the interpretation of neural mechanisms of acupuncture treatment for migraine.

Abstract

关键词

acupuncturemigraine without auraresting-statefunctional connectivityfunctional magnetic resonance imaging

Keywords

acupuncturemigraine without auraresting-statefunctional connectivityfunctional magnetic resonance imaging

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Acupuncture and Moxibustion Department, Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University

The First Hospital Affiliated to Tianjin University of Traditional Chinese Medicine

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