Effect of Huanshuai Recipe Oral Liquid (缓衰口服液) on renal dysfunction progression in patients with atherosclerotic renal artery stenosis

Xiu-juan Wang; Xiang-rong Rao; Shen Li; Li Wang; Chang Liu; Gai-hua Zhang; Dong-yan Han; Yu Zhao; Nan-nan Zhang; Xue-xia Li; Shuai Chen

doi:10.1007/s11655-015-2046-0

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Effect of Huanshuai Recipe Oral Liquid (缓衰口服液) on renal dysfunction progression in patients with atherosclerotic renal artery stenosis

Updated：2021-08-27

- Effect of Huanshuai Recipe Oral Liquid (缓衰口服液) on renal dysfunction progression in patients with atherosclerotic renal artery stenosis
- Chinese Journal of Integrative Medicine Vol. 21, Issue 11, Pages: 811-816(2015)
- Affiliations：
  
  1. Department of Nephropathy, Guang’anmen Hospital, China Academy of Chinese Medical Sciences,Beijing,China
  2. Department of Nephropathy, Beijing Fangshan Hospital of Traditional Chinese Medicine,Beijing,China
  3. Department of Nephropathy, The Second People’s Hospital of Zhuhai,Guangdong Province,Zhuhai,China
  4. Department of Nephropathy, Beijing Miyun Hospital of Traditional Chinese Medicine,Beijing,China
- Author bio：
- Funds：
- DOI：10.1007/s11655-015-2046-0
  CLC：
- Published：2015，
  
  Published Online：6 April 2015，
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Wang, Xj., Rao, Xr., Li, S. et al. Effect of Huanshuai Recipe Oral Liquid (缓衰口服液) on renal dysfunction progression in patients with atherosclerotic renal artery stenosis., Chin. J. Integr. Med. 21, 811–816 (2015). https://doi.org/10.1007/s11655-015-2046-0

Xiu-juan Wang, Xiang-rong Rao, Shen Li, et al. Effect of Huanshuai Recipe Oral Liquid (缓衰口服液) on renal dysfunction progression in patients with atherosclerotic renal artery stenosis. [J]. Chinese Journal of Integrative Medicine 21(11):811-816(2015)
Wang, Xj., Rao, Xr., Li, S. et al. Effect of Huanshuai Recipe Oral Liquid (缓衰口服液) on renal dysfunction progression in patients with atherosclerotic renal artery stenosis., Chin. J. Integr. Med. 21, 811–816 (2015). https://doi.org/10.1007/s11655-015-2046-0 DOI：

Xiu-juan Wang, Xiang-rong Rao, Shen Li, et al. Effect of Huanshuai Recipe Oral Liquid (缓衰口服液) on renal dysfunction progression in patients with atherosclerotic renal artery stenosis. [J]. Chinese Journal of Integrative Medicine 21(11):811-816(2015) DOI： 10.1007/s11655-015-2046-0.

摘要

To investigate the effect of Huanshuai Recipe Oral Liquid (缓衰口服液

HSR) on retarding the progression of renal dysfunction in patients with atherosclerotic renal artery stenosis (ARAS). A total of 52 ARAS patients with the Chinese medicine (CM) syndrome of qi deficiency and blood stasis

phlegm and dampness retention were recruited and randomly assigned into the treatment group (36 cases) and the control group (16 cases). Both groups received a basic treatment (high-quality low-protein diet

blood pressure control

lipid-lowering

correcting the acidosis

etc.). In addition

the treatment group received 20 mL HSR and the control group received placebo

3 times a day for 6 months. Renal function (serum creatinine

blood urea nitrogen and uric acid) and blood lipids (cholesterol

triglycerides and low density lipoprotein) were examined monthly. The estimated glomerular fifiltration rate (eGFR) and CM syndrome score were compared between groups. After treatment

compared with the control group

the serum creatinine level

uric acid level and CM syndrome score of the treatment group were signifificantly decreased (P<0.05 or P<0.01)

and the eGFR in the treatment group were significantly increased (P<0.05). HSR can effectively improve the renal function and clinical symptoms of ARAS patients.

Abstract

To investigate the effect of Huanshuai Recipe Oral Liquid (缓衰口服液

blood pressure control

lipid-lowering

correcting the acidosis

etc.). In addition

the treatment group received 20 mL HSR and the control group received placebo

3 times a day for 6 months. Renal function (serum creatinine

blood urea nitrogen and uric acid) and blood lipids (cholesterol

triglycerides and low density lipoprotein) were examined monthly. The estimated glomerular fifiltration rate (eGFR) and CM syndrome score were compared between groups. After treatment

compared with the control group

the serum creatinine level

uric acid level and CM syndrome score of the treatment group were signifificantly decreased (P<0.05 or P<0.01)

and the eGFR in the treatment group were significantly increased (P<0.05). HSR can effectively improve the renal function and clinical symptoms of ARAS patients.

关键词

atherosclerotic renal artery stenosisHuanshuai Recipe Oral LiquidRenal DysfunctionChinese Medicine

Keywords

atherosclerotic renal artery stenosisHuanshuai Recipe Oral LiquidRenal DysfunctionChinese Medicine

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