Ginkgo Biloba extract for angina pectoris: A systematic review

Tian Sun; Xian Wang; Hao Xu

doi:10.1007/s11655-015-2070-0

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Ginkgo Biloba extract for angina pectoris: A systematic review

Updated：2021-08-27

- Ginkgo Biloba extract for angina pectoris: A systematic review
- Chinese Journal of Integrative Medicine Vol. 21, Issue 7, Pages: 542-550(2015)
- Affiliations：
  
  1. Graduate School, Beijing University of Chinese Medicine,Beijing,China
  2. Cardiovascular Diseases Center, Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine,Beijing,China
  3. Beijing University Cardiology Research Institute of Traditional Chinese Medicine,Beijing,China
  4. Cardiovascular Diseases Center, Xiyuan Hospital, China Academy of Chinese Medical Sciences,Beijing,China
- Author bio：
- Funds：
  
  Supported by the Graduate Student Projects of Beijng University of Chinese Medicine (No. 2014-JYBZZ-XS-133)
- DOI：10.1007/s11655-015-2070-0
  CLC：
- Published：2015，
  
  Published Online：6 March 2015，
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Sun, T., Wang, X. & Xu, H. , Ginkgo Biloba extract for angina pectoris: A systematic review., Chin. J. Integr. Med. 21, 542–550 (2015). https://doi.org/10.1007/s11655-015-2070-0

Tian Sun, Xian Wang, Hao Xu. Ginkgo Biloba extract for angina pectoris: A systematic review. [J]. Chinese Journal of Integrative Medicine 21(7):542-550(2015)
Sun, T., Wang, X. & Xu, H. , Ginkgo Biloba extract for angina pectoris: A systematic review., Chin. J. Integr. Med. 21, 542–550 (2015). https://doi.org/10.1007/s11655-015-2070-0 DOI：

Tian Sun, Xian Wang, Hao Xu. Ginkgo Biloba extract for angina pectoris: A systematic review. [J]. Chinese Journal of Integrative Medicine 21(7):542-550(2015) DOI： 10.1007/s11655-015-2070-0.

摘要

To evaluate the efficacy and safety of Ginkgo Biloba extract for patients with angina pectoris according to the available evidence. Electronic databases were searched for all of the randomized controlled trials (RCTs) of angina pectoris treatments with Ginkgo Biloba extract

either alone or combined with routine Western medicine (RWM)

and controlled by untreated

placebo

Chinese patent medicine

or RWM treatment. The RCTs were retrieved from the following electronic databases: PubMed/MEDLINE

ProQuest Health and Medical Complete

Springer

Elsevier

and ProQuest Dissertations and Theses

Wanfang Data

China National Knowledge Infrastructure (CNKI)

VIP database

China Biology Medicine (CBM)

Chinese Medical Citation Index (CMCI)

from the earliest database records to December 2012. No language restriction was applied. Study selection

data extraction

quality assessment

and data analyses were conducted according to the Cochrane standards. RevMan 5.1.0 provided by Cochrane Collaboration The data were analysed by using. A total of 23 RCTs (involving 2

529 patients) were included and the methodological quality was evaluated as generally low. Ginkgo Biloba extract with RWM was more effective in angina relief and electrocardiogram improvement than RWM alone. Reported adverse events included epigastric discomfort

nausea

gastrointestinal reaction

and bitter taste. Ginkgo Biloba extract may have beneficial effects on patients with angina pectoris

although the low quality of existing trials makes it difficult to draw a satisfactory conclusion. More rigorous

high quality clinical trials are needed to provide conclusive evidence.

Abstract

either alone or combined with routine Western medicine (RWM)

and controlled by untreated

placebo

Chinese patent medicine

or RWM treatment. The RCTs were retrieved from the following electronic databases: PubMed/MEDLINE

ProQuest Health and Medical Complete

Springer

Elsevier

and ProQuest Dissertations and Theses

Wanfang Data

China National Knowledge Infrastructure (CNKI)

VIP database

China Biology Medicine (CBM)

Chinese Medical Citation Index (CMCI)

from the earliest database records to December 2012. No language restriction was applied. Study selection

data extraction

quality assessment

and data analyses were conducted according to the Cochrane standards. RevMan 5.1.0 provided by Cochrane Collaboration The data were analysed by using. A total of 23 RCTs (involving 2

nausea

gastrointestinal reaction

and bitter taste. Ginkgo Biloba extract may have beneficial effects on patients with angina pectoris

although the low quality of existing trials makes it difficult to draw a satisfactory conclusion. More rigorous

high quality clinical trials are needed to provide conclusive evidence.

关键词

Ginkgo Bilobaextractangina pectorissystematic reviewChinese Medicine

Keywords

Ginkgo Bilobaextractangina pectorissystematic reviewChinese Medicine

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Guang’anmen Hospital, China Academy of Chinese Medical Sciences

Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences

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Department of Traditional Chinese Medicine, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences

The First Hospital of Beijing University of Chinese Medicine

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