Clinical presentation and treatment strategies for ulcerative colitis: A retrospective study of 247 inpatients

Yan-cheng Dai; Ya-li Zhang; Li-juan Wang; Qian Guo; Kun Yang; Ren-hao Ye; Zhi-peng Tang

doi:10.1007/s11655-015-2118-1

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Clinical presentation and treatment strategies for ulcerative colitis: A retrospective study of 247 inpatients

Updated：2021-08-27

- Clinical presentation and treatment strategies for ulcerative colitis: A retrospective study of 247 inpatients
- Chinese Journal of Integrative Medicine Vol. 22, Issue 11, Pages: 811-816(2016)
- Affiliations：
  
  Department of Gastroenterology, Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Institute of Digestive Disease Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai,China
- Author bio：
- Funds：
  
  Supported by the National Natural Science Foundation of China (No. 81403355), the Young Foundation of Shanghai Health and Family Planning Commission (No. 20034y170), and the New Star Project of Shanghai Health and Family Planning Commission (No. ZY3-RCPY-2-2001)
- DOI：10.1007/s11655-015-2118-1
  CLC：
- Published：2016，
  
  Published Online：26 October 2015，
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Dai, Yc., Zhang, Yl., Wang, Lj. et al. Clinical presentation and treatment strategies for ulcerative colitis: A retrospective study of 247 inpatients., Chin. J. Integr. Med. 22, 811–816 (2016). https://doi.org/10.1007/s11655-015-2118-1

Yan-cheng Dai, Ya-li Zhang, Li-juan Wang, et al. Clinical presentation and treatment strategies for ulcerative colitis: A retrospective study of 247 inpatients. [J]. Chinese Journal of Integrative Medicine 22(11):811-816(2016)
Dai, Yc., Zhang, Yl., Wang, Lj. et al. Clinical presentation and treatment strategies for ulcerative colitis: A retrospective study of 247 inpatients., Chin. J. Integr. Med. 22, 811–816 (2016). https://doi.org/10.1007/s11655-015-2118-1 DOI：

Yan-cheng Dai, Ya-li Zhang, Li-juan Wang, et al. Clinical presentation and treatment strategies for ulcerative colitis: A retrospective study of 247 inpatients. [J]. Chinese Journal of Integrative Medicine 22(11):811-816(2016) DOI： 10.1007/s11655-015-2118-1.

摘要

Complementary and alternative medicine

particularly herbal therapy

is widely used by patients with ulcerative colitis (UC)

but controlled data are limited. To describe the clinical presentation and treatment strategies for UC in inpatients from Shanghai

China and to improve the therapeutic outcomes for patients with UC. Medical records from 247 patients with UC who were admitted to Longhua Hospital Affifiliated to Shanghai University of Traditional Chinese Medicine between January 2008 and June 2013 were analyzed for gender

age

course of the disease

clinical type

extent and severity of the disease

treatment strategies

and therapeutic outcomes. Gender ratios and disease onset of inpatients with UC in the Shanghai area were consistent with other reports in the literature. In contrast to previous studies

most patients exhibited disease of the left colon

over half of the patients had problems of the rectum or sigmoid colon

and most patients had either mild or moderate UC. Comparison of Sutherland Disease Actirity Index scores for patients treated with Chinese medicine (CM) and those treated with integrated CM and Western medicine revealed signifificant reductions in scores for both groups after treatment (P<0.01)

with no signifificant difference in therapeutic effects between groups (P=0.938). Herbal medicine has been widely used in patients with mild to moderate disease and as adjunct therapy in patients with moderate to severe disease. Therefore

the strategy was proposed for the treatment of UC with CM therapy based on 2 steps according to the stage of the disease

even in the clinical setting.

Abstract

Complementary and alternative medicine

particularly herbal therapy

is widely used by patients with ulcerative colitis (UC)

but controlled data are limited. To describe the clinical presentation and treatment strategies for UC in inpatients from Shanghai

age

course of the disease

clinical type

extent and severity of the disease

treatment strategies

and therapeutic outcomes. Gender ratios and disease onset of inpatients with UC in the Shanghai area were consistent with other reports in the literature. In contrast to previous studies

most patients exhibited disease of the left colon

over half of the patients had problems of the rectum or sigmoid colon

the strategy was proposed for the treatment of UC with CM therapy based on 2 steps according to the stage of the disease

even in the clinical setting.

关键词

Ulcerative ColitisChinese Medicineretrospective studytreatment strategy

Keywords

Ulcerative ColitisChinese Medicineretrospective studytreatment strategy

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