In vitro antifungal activity of some traditional Persian medicinal plants on pathogenic fungi

Jinous Asgarpanah; Seyyed Jamal Hashemi; Elham Hashemi; Kiana Askari

doi:10.1007/s11655-015-2181-7

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In vitro antifungal activity of some traditional Persian medicinal plants on pathogenic fungi

Updated：2021-08-27

- In vitro antifungal activity of some traditional Persian medicinal plants on pathogenic fungi
- Chinese Journal of Integrative Medicine Vol. 23, Issue 6, Pages: 433-437(2017)
- Affiliations：
  
  1. Young Researchers and Elite Club, Pharmaceutical Sciences Branch, Islamic Azad University, Tehran,Iran
  2. Department of Pharmacognosy, Faculty of Pharmacy, Pharmaceutical Sciences Branch, Islamic Azad University, Tehran,Iran
  3. Department of Medical Mycology and Parasitology, School of Public Health, Tehran University of Medical Sciences, Tehran,Iran
- Author bio：
- Funds：
- DOI：10.1007/s11655-015-2181-7
  CLC：
- Published：2017，
  
  Published Online：1 July 2015，
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Asgarpanah, J., Hashemi, S.J., Hashemi, E. et al. , In vitro antifungal activity of some traditional Persian medicinal plants on pathogenic fungi., Chin. J. Integr. Med. 23, 433–437 (2017). https://doi.org/10.1007/s11655-015-2181-7

Jinous Asgarpanah, Seyyed Jamal Hashemi, Elham Hashemi, et al. In vitro antifungal activity of some traditional Persian medicinal plants on pathogenic fungi. [J]. Chinese Journal of Integrative Medicine 23(6):433-437(2017)
Asgarpanah, J., Hashemi, S.J., Hashemi, E. et al. , In vitro antifungal activity of some traditional Persian medicinal plants on pathogenic fungi., Chin. J. Integr. Med. 23, 433–437 (2017). https://doi.org/10.1007/s11655-015-2181-7 DOI：

Jinous Asgarpanah, Seyyed Jamal Hashemi, Elham Hashemi, et al. In vitro antifungal activity of some traditional Persian medicinal plants on pathogenic fungi. [J]. Chinese Journal of Integrative Medicine 23(6):433-437(2017) DOI： 10.1007/s11655-015-2181-7.

摘要

To investigate the antifungal activities of the extracts and sub-fractions of Phlomis olivieri

Verbascum speciosum

Sambucus ebulus and Erigeron hyrcanicus

four Persian medicinal plants used in Iranian folk medicine. Evaluation of the antifungal activity was performed on the clinical isolates of pathogenic fungi including Aspergillus fumigatus

A. flavus

Trichophyton mentagrophytes

T. rubrum

T. verrucosum

Microsporum canis

M. gypseum and Epidermophyton floccosum

and the yeast Candida albicans. The susceptibility tests were done by agar well diffusion method. The minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC) of active extracts and sub-fractions were measured using method of National Committee for Clinical Laboratory Standards (NCCLS). Only P. olivieri sub-fractions were found to have fungicidal activity among the other investigated plants. The MIC and MFC was found to be high in petroleum ether

chloroform and ethyl acetate fractions (100 and 200 mg/mL) against the studied pathogenic fungi and the yeast Candida albicans. P. olivieri sub-fractions significantly inhibited the growth of all pathogenic fungi and the yeast studied. If the antifungal activity of P. olivieri is confirmed by in vivo studies and if the responsible compound (s) is isolated and identified

it could be a good remedy for mycotic infections.

Abstract

To investigate the antifungal activities of the extracts and sub-fractions of Phlomis olivieri

Verbascum speciosum

Sambucus ebulus and Erigeron hyrcanicus

four Persian medicinal plants used in Iranian folk medicine. Evaluation of the antifungal activity was performed on the clinical isolates of pathogenic fungi including Aspergillus fumigatus

A. flavus

Trichophyton mentagrophytes

T. rubrum

T. verrucosum

Microsporum canis

M. gypseum and Epidermophyton floccosum

it could be a good remedy for mycotic infections.

关键词

antifungal activityPhlomis olivieriVerbascum speciosumSambucus ebulusErigeron hyrcanicus

Keywords

antifungal activityPhlomis olivieriVerbascum speciosumSambucus ebulusErigeron hyrcanicus

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