Recent highlights of experimental research for inhibiting tumor growth by using Chinese medicine

Xi-ran He; Shu-yan Han; Ping-ping Li

doi:10.1007/s11655-015-2318-8

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Recent highlights of experimental research for inhibiting tumor growth by using Chinese medicine

Updated：2021-08-27

- Recent highlights of experimental research for inhibiting tumor growth by using Chinese medicine
- Chinese Journal of Integrative Medicine Vol. 21, Issue 10, Pages: 727-732(2015)
- Affiliations：
  
  Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Integration of Traditional Chinese and Western Medicine, Peking University School of Oncology, Peking University Cancer Hospital & Institute,Beijing,China
- Author bio：
- Funds：
- DOI：10.1007/s11655-015-2318-8
  CLC：
- Published：2015，
  
  Published Online：3 November 2015，
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He, Xr., Han, Sy. & Li, Pp. Recent highlights of experimental research for inhibiting tumor growth by using Chinese medicine., Chin. J. Integr. Med. 21, 727–732 (2015). https://doi.org/10.1007/s11655-015-2318-8

Xi-ran He, Shu-yan Han, Ping-ping Li. Recent highlights of experimental research for inhibiting tumor growth by using Chinese medicine. [J]. Chinese Journal of Integrative Medicine 21(10):727-732(2015)
He, Xr., Han, Sy. & Li, Pp. Recent highlights of experimental research for inhibiting tumor growth by using Chinese medicine., Chin. J. Integr. Med. 21, 727–732 (2015). https://doi.org/10.1007/s11655-015-2318-8 DOI：

Xi-ran He, Shu-yan Han, Ping-ping Li. Recent highlights of experimental research for inhibiting tumor growth by using Chinese medicine. [J]. Chinese Journal of Integrative Medicine 21(10):727-732(2015) DOI： 10.1007/s11655-015-2318-8.

摘要

To give an overview of contemporary experimental research using Chinese medicine (CM) for the treatment of cancer. As an integral part of mainstream medicine in the People’s Republic of China

CM emphasizes improvements in holistic physical condition instead of merely killing tumor cells

which is consistent with the current medical model that advocates patient-oriented treatment. Great progress has been made in experimental research

and the principle aspects include anti-tumor angiogenesis

inducing apoptosis and differentiation

reversing multidrug resistance

and improving immune function. As a current hot topic in cancer research

tumor microenvironment (TME) highlights the mutual and interdependent interaction between tumor cells and their surrounding tissues

and the CM treatment concept bears a striking resemblance to it. To date

primary points of TME include extracellular matrix remodeling

inflfl ammation

hypoxia

and angiogenesis

but trials using CM with a focus on TME are rare. Despite considerable recent development

experimental research on CM for solving cancer issues appears insufficient. Greater efforts in this field are urgently needed.

Abstract

To give an overview of contemporary experimental research using Chinese medicine (CM) for the treatment of cancer. As an integral part of mainstream medicine in the People’s Republic of China

CM emphasizes improvements in holistic physical condition instead of merely killing tumor cells

which is consistent with the current medical model that advocates patient-oriented treatment. Great progress has been made in experimental research

and the principle aspects include anti-tumor angiogenesis

inducing apoptosis and differentiation

reversing multidrug resistance

and improving immune function. As a current hot topic in cancer research

tumor microenvironment (TME) highlights the mutual and interdependent interaction between tumor cells and their surrounding tissues

and the CM treatment concept bears a striking resemblance to it. To date

primary points of TME include extracellular matrix remodeling

inflfl ammation

hypoxia

and angiogenesis

but trials using CM with a focus on TME are rare. Despite considerable recent development

experimental research on CM for solving cancer issues appears insufficient. Greater efforts in this field are urgently needed.

关键词

Chinese Medicinetumorexperimental researchhighlights

Keywords

Chinese Medicinetumorexperimental researchhighlights

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Beijing Cancer Hospital & Institute, Peking University School of Oncology

Key Laboratory of Nanobiological Technology of Chinese Ministry of Health, Xiangya Hospital, Central South University

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Department of Pharmacy, Tongren Hospital, Shanghai Jiaotong University, School of Medicine

Cancer Research Institute, Collaborative Innovation Center for Cancer Medicine, Key Laboratory for Carcinogenesis of Chinese Ministry of Health, School of Basic Medical Science, Central South University

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