An overview of epigenetics in Chinese medicine researches

Xue-qing Hu; Shi-bing Su

doi:10.1007/s11655-016-2274-y

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An overview of epigenetics in Chinese medicine researches

Updated：2021-08-27

- An overview of epigenetics in Chinese medicine researches
- Chinese Journal of Integrative Medicine Vol. 23, Issue 9, Pages: 714-720(2017)
- Affiliations：
  
  Research Center for Traditional Chinese Medicine Complexity System, Shanghai University of Traditional Chinese Medicine,Shanghai,China
- Author bio：
- Funds：
  
  Supported by the Key Program of National Natural Science Foundation of China (No. 81330084), "085" First-Class Discipline Construction Innovation Science and Technology Support Project of Shanghai University of Traditional Chinese Medicine (No. 085ZY1206) and E-Institutes of Shanghai Municipal Education Commission (No. E 03008);Conflict of Interests;The authors declare that they have no competing interests.;Author Contributions;Su SB designed and revised the review. Hu XQ drafted the manuscript. All authors read and approved the final manuscript.;Electronic Supplementary Material;: Supplementary material (Appendixes) is available in the online version of this article at http:// DOI: 10.1007/s11655-016-2274-y
- DOI：10.1007/s11655-016-2274-y
  CLC：
- Published：2017，
  
  Published Online：20 December 2016，
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Hu, Xq., Su, Sb. An overview of epigenetics in Chinese medicine researches., Chin. J. Integr. Med. 23, 714–720 (2017). https://doi.org/10.1007/s11655-016-2274-y

Xue-qing Hu, Shi-bing Su. An overview of epigenetics in Chinese medicine researches. [J]. Chinese Journal of Integrative Medicine 23(9):714-720(2017)
Hu, Xq., Su, Sb. An overview of epigenetics in Chinese medicine researches., Chin. J. Integr. Med. 23, 714–720 (2017). https://doi.org/10.1007/s11655-016-2274-y DOI：

Xue-qing Hu, Shi-bing Su. An overview of epigenetics in Chinese medicine researches. [J]. Chinese Journal of Integrative Medicine 23(9):714-720(2017) DOI： 10.1007/s11655-016-2274-y.

摘要

Chinese medicine (CM) has contributed to human health care for several thousand years and is still popular in Asian countries. But the mechanisms underlying CM remain obscure

and need to be clarifified by modern biological subjects and methods. Recently

CM researches on epigenetics have gained obvious improvement following rapidly developed molecular technologies. In this review

we revealed mutual characteristics of epigenetics and CM

such as holism

yin-yang dynamic nature

reversibility and balance

and visceral manifestation. Moreover

epigenetic modifications

including DNA methylation

histone post-transcriptional modifications

micro RNA interference

etc. may help explore the molecular basis of CM syndrome classifification

and mechanisms of Chinese herbal medicine (CHM)

CHM compounds and Chinese herbal formulae activities. Meanwhile

CM and epigenetics might promote each other and jointly develop following the continuous progress of epigenetics in CM researches.

Abstract

Chinese medicine (CM) has contributed to human health care for several thousand years and is still popular in Asian countries. But the mechanisms underlying CM remain obscure

and need to be clarifified by modern biological subjects and methods. Recently

CM researches on epigenetics have gained obvious improvement following rapidly developed molecular technologies. In this review

we revealed mutual characteristics of epigenetics and CM

such as holism

yin-yang dynamic nature

reversibility and balance

and visceral manifestation. Moreover

epigenetic modifications

including DNA methylation

histone post-transcriptional modifications

micro RNA interference

etc. may help explore the molecular basis of CM syndrome classifification

and mechanisms of Chinese herbal medicine (CHM)

CHM compounds and Chinese herbal formulae activities. Meanwhile

CM and epigenetics might promote each other and jointly develop following the continuous progress of epigenetics in CM researches.

关键词

Chinese Medicineepigeneticsmethylationhistone modificationChinese Herbal MedicineChinese herbal formulaChinese medicine syndrome

Keywords

Chinese Medicineepigeneticsmethylationhistone modificationChinese Herbal MedicineChinese herbal formulaChinese medicine syndrome

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