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Electrical stimulation of auricular acupressure for dry eye: A randomized controlled-clinical trial
- Chinese Journal of Integrative Medicine Vol. 23, Issue 11, Pages: 822-828(2017)
- Affiliations：
1. Department of Ophthalmology, School of Medicine, Pusan National University and Medical Research Institute, Pusan National University Hospital, Pusan, Republic of Korea
2. Department of Ophthalmology, Jung’s Eye Center, Pusan, Republic of Korea
3. Division of Clinical Medicine, School of Korean Medicine, Pusan National University, Yangsan, Republic of Korea
4. Department of Ophthalmology, Gyeongsang National University School of Medicine, Gyeongsang National University Changwon Hospital, Changwon, Republic of Korea
- Author bio：
- Funds：
DOI：10.1007/s11655-016-2449-6
CLC：Published：2017，
Published Online：13 April 2016，
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Lee, J.S., Hwang, S.H., Shin, B.C. et al. Electrical stimulation of auricular acupressure for dry eye: A randomized controlled-clinical trial., Chin. J. Integr. Med. 23, 822–828 (2017). https://doi.org/10.1007/s11655-016-2449-6
Jong Soo Lee, Sang Ho Hwang, Byung Cheul Shin, et al. Electrical stimulation of auricular acupressure for dry eye: A randomized controlled-clinical trial. [J]. Chinese Journal of Integrative Medicine 23(11):822-828(2017)
Lee, J.S., Hwang, S.H., Shin, B.C. et al. Electrical stimulation of auricular acupressure for dry eye: A randomized controlled-clinical trial., Chin. J. Integr. Med. 23, 822–828 (2017). https://doi.org/10.1007/s11655-016-2449-6 DOI：
Jong Soo Lee, Sang Ho Hwang, Byung Cheul Shin, et al. Electrical stimulation of auricular acupressure for dry eye: A randomized controlled-clinical trial. [J]. Chinese Journal of Integrative Medicine 23(11):822-828(2017) DOI： 10.1007/s11655-016-2449-6.
摘要
To evaluate the clinical efficacy of electrical stimulation (ES) of auricular acupressure on reducing the ocular symptoms and signs before and after treatment for dry eye. The inclusion criteria were the tear film break-up time (TFBUT) below 5 s and a Schirmer test-I below 5 mm in dry eyes with ocular symptoms for at least 6 months. Subjects were randomized into a treatment group (50 cases) with continuous low frequency ES under auricular acupressure at acupoints and a no ES under auricular acupressure (no-ES
control group
50 cases) on the same acupoints. Auricular acupressure were stimulated with ES at 4 master points of both ears
which were performed twice a week for 4 weeks at each point for 30 s. The ocular symptoms
the TFBUT
and Schirmer test-I were evaluated before and after this procedure. There were significantly better scores in TFBUT (P=0.032)
the Schirmer test-I (P=0.044) and ocular symptoms (P=0.029) at 3 months post-treatment in the treatment group than in the control group. The total effective rate in the treatment group was accomplished in 41 (82%) of the 50 cases of dry eye. Auricular acupressure with ES at auricular acupoint improves ocular symptoms and signs of dry eye for a period of at least 3 months.
Abstract
To evaluate the clinical efficacy of electrical stimulation (ES) of auricular acupressure on reducing the ocular symptoms and signs before and after treatment for dry eye. The inclusion criteria were the tear film break-up time (TFBUT) below 5 s and a Schirmer test-I below 5 mm in dry eyes with ocular symptoms for at least 6 months. Subjects were randomized into a treatment group (50 cases) with continuous low frequency ES under auricular acupressure at acupoints and a no ES under auricular acupressure (no-ES
control group
50 cases) on the same acupoints. Auricular acupressure were stimulated with ES at 4 master points of both ears
which were performed twice a week for 4 weeks at each point for 30 s. The ocular symptoms
the TFBUT
and Schirmer test-I were evaluated before and after this procedure. There were significantly better scores in TFBUT (P=0.032)
the Schirmer test-I (P=0.044) and ocular symptoms (P=0.029) at 3 months post-treatment in the treatment group than in the control group. The total effective rate in the treatment group was accomplished in 41 (82%) of the 50 cases of dry eye. Auricular acupressure with ES at auricular acupoint improves ocular symptoms and signs of dry eye for a period of at least 3 months.
关键词
auricular acupressuredry eye syndromeselectrical stimulationtears
Keywords
auricular acupressuredry eye syndromeselectrical stimulationtears
references
Kavoussi B, Ross BE. The neuroimmune basis of antiinflammatory acupuncture. Integr Cancer Ther 2007;6:251–257.
Uchida S, Hotta H. Acupuncture affects regional blood flow in various organs. Evid Based Complement Alternat Med 2008;5:145–151.
Gong L, Sun X. Treatment of intractable dry eyes: tear secretion increase and morphological changes of the lacrimal gland of rabbit after acupuncture. Acupunct Electrother Res 2007;32:223–233.
Greif R, Laciny S, Mokhtarani M, Doufas AG, Bakhshandeh M, Dorfer L, et al. Transcutaneous electrical stimulation of an auricular acupuncture point decreases anesthetic requirement. Anesthesiology 2002;96:306–312.
Tolksdorf W, Ewen T, Kattermann R, Klose R, Lutz H. Electrostimulation anaesthesia and neurolept anaesthesia for cholecystectomy. A comparative study. Anaesthesist 1980;29:459–463.
Fischer M, Just OH, Maric D. Electrostimulation anaesthesia for surgery of the limbs. Prakt Anaesth 1979;14:8–13.
Han JS, Terenius L. Neurochemical basis of acupuncture analgesia. Annu Rev Pharmacol Toxicol 1982;22:193–220.
Tang NM, Dong HW, Wang XM, Tsui ZC, Han JS. Cholecystokinin antisense RNA increases the analgesic effect induced by electroacupuncture or low dose morphine: conversion of low responder rats into high responders. Pain 1997;71:71–80.
Dawidson I, Angmar-Månsson B, Blom M, Theodorsson E, Lundeberg T. Sensory stimulation (acupuncture) increases the release of vasoactive intestinal polypeptide in the saliva of xerostomia sufferers. Neuropeptides 1998;32:543–548
Mayer DJ. Biological mechanism of acupuncture. Prog Brain Res 2000;122:457–477.
Bai H, Yu P, Yu M. Effect of electroacupuncture on sex hormone levels in patients with Sjogren's syndrome. Acupunct Res (Chin) 2007;32:203–206.
The definition and classification of dry eye disease: Report of the Definition and Classification Subcommittee of the International Dry Eye Workshop (2007). Ocul Surf 2007;5:75–92.
Liu XQ, Zhu HY, Ruan WJ. Clinical study on combined acupuncture and Chinese medicinal fumigation for dry eye syndrome. J Acupunct Tunia Sci 2013;11:79–83.
Burstein NL. The effects of topical drugs and preservatives on the tears and corneal epithelium in dry eye. Trans Ophthalmol Soc U K 1985;104:402–409.
Burstein NL. Corneal cytotoxicity of topically applied drugs, vehicles and preservatives. Surv Ophthalmol 1980;25:15–30.
Diestelhorst M, Grunthal S, Suverkrup R. Dry drops: a new preservatives-free drug delivery system. Graefes Arch Clin Exp Ophthalmol 1990;237:394–398.
Murube J, Murube E. Treatment of dry eye by blocking the lacrimal canaliculi. Surv Ophthalmol 1996;40:463–480.
Pflugfelder SC, Jones D, Ji Z, Afonso A, Monroy D. Altered cytokine balance in the tear fluid and conjunctiva of patients with Sjogren's syndrome keratoconjunctivitis sicca. Curr Eye Res 1999;19:201–211.
Nelson JD, Friedlaender M, Yeatts RP, Yee R, McDermott M, Orlin S, et al. Oral pilocarpine for symptomatic relief of keratoconjunctivitis sicca in patients with Sjogren's syndrome. The MGI PHARMA Sjogren's Syndrome Study Group. Adv Exp Med Biol 1998;438:979–983.
Lee MS, Shin BC, Choi TY, Ernst E. Acupuncture for treating dry eye: a systemic review. Acta Ophthalmol 2011;89:101–106.
Wang ZL, He HQ, Huang D, Shi CG. Effect of integral syndrome differentiation acupuncture on the tear film stability in the patient of xerophthalmia. Chin Acupunct (Chin) 2005;25:460–463.
Stux G, Pomeranz B, eds. Basics of acupuncture. 4th ed. Berlin: Springer; 1998.
Tseng KL, Liu HJ, Tso KY, Woung LC, Su YC, Lin JG. A clinical study of acupuncture and SSP (silver spike point) electro-therapy for dry eye syndrome. Am J Chin Med 2006;34:197–206.
Kim TH, Kang JW, Kim KH, Kang KW, Shin MS, Jung SY, et al. Acupuncture for the treatment of dry eye: a multicenter randomised controlled trial with active comparison intervention (artificial teardrops). PLoS One 2012;7:36638.
Yang W, Zhang YC, Liu D, Sun H, Chen LQ. Clinical observation on the method for nourishing blood and moisturizing eye on xerophthalmia. Chin Acupunct (Chin) 2006;26:571–573.
Goertz CM, Niemtzow R, Burns SM, Fritts MJ, Crawford CC, Jonas WB. Auricular acupuncture in the treatment of acute pain syndromes: A pilot study. Mil Med 2006;171:1010–1014.
Shin MS, Kim JI, Lee MS, Kim KH, Choi JY, Kang KW, et al. Acupuncture for treating dry eye: a randomized placebocontrolled trial. Acta Ophthalmol 2010;88:328–333.
Park JE, Lee MS, Choi JY, Kim BY, Choi SM. Adverse events associated with acupuncture: a prospective survey. J Altern Complement Med 2010;16:959–963.
Zhao L, Zhang FW, Li Y, Wu X, Zheng H, Cheng LH, et al. Adverse events associated with acupuncture: three multicentre randomized controlled trials of 1968 cases in China. Trials 2011;24;12–87.
Witt CM, Pach D, Reinhold T, Wruck K, Brinkhaus B, Mank S, et al. Treatment of the adverse effects from acupuncture and their economic impact: a prospective study in 73,406 patients with low back or neck pain. Eur J Pain 2011;15:193–197.
Lemp MA, Bron AJ, Baudouin C, Benítez Del, Castillo JM, Geffen D, et al. Tear osmolarity in the diagnosis and management of dry eye disease. Am J Ophthalmol 2011;151:792–798.
Riederer P, Tenk H, Werner H, Bischko J, Rett A, Krisper H. Manipulation of neurotransmitters by acupuncture (a preliminary communication). J Neural Transm 1975;37:81–94.
Reichmanis M, Marino AA, Becker RO. Electrical correlates of acupuncture points. IEEE Trans Biomed Eng 1975;22: 533–535.
Oke SL, Tracey KJ. The inflammatory reflex and the role of complementary and alternative medical therapies. Ann N Y Acad Sci 2009;1172:172–180.
Nepp J, Jandrasits K, Schauersberger J, Schild G, Wedrich A, Sabine GL, et al. Is acupuncture an useful tool for paintreatment in ophthalmology? Acupunct Electrother Res 2002;27:171–182.
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