Association between skin reactions and efficacy of summer acupoint application treatment on chronic pulmonary disease: A prospective study

Xia-qiu Wu; Jin Peng; Guo-qin Li; Hui-ping Su; Guang-xia Liu; Bao-yan Liu

doi:10.1007/s11655-016-2497-y

Your Location：

Home >

Browse articles >

Association between skin reactions and efficacy of summer acupoint application treatment on chronic pulmonary disease: A prospective study

Updated：2021-08-27

- Association between skin reactions and efficacy of summer acupoint application treatment on chronic pulmonary disease: A prospective study
- Chinese Journal of Integrative Medicine Vol. 22, Issue 4, Pages: 284-292(2016)
- Affiliations：
  
  1. Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences,Beijing,China
  2. Department of Respiration, Guang’anmen Hospital, China Academy of Chinese Medical Sciences,Beijing,China
  3. Department of Respiration, Dongzhimen Hospital, Beijing University of Chinese Medicine,Beijing,China
  4. Department of Respiration, Affiliated Hospital of Anhui University of Traditional Chinese Medicine,Hefei,China
  5. China Academy of Chinese Medical Sciences,Beijing,China
- Author bio：
- Funds：
  
  Supported by the National Key Technology Research and Development Program for the Eleventh Five-Year Plan of China (No. 2008BAI53B061)
- DOI：10.1007/s11655-016-2497-y
  CLC：
- Published：2016，
  
  Published Online：9 April 2016，
Scan for full text
Wu, Xq., Peng, J., Li, Gq. et al. Association between skin reactions and efficacy of summer acupoint application treatment on chronic pulmonary disease: A prospective study., Chin. J. Integr. Med. 22, 284–292 (2016). https://doi.org/10.1007/s11655-016-2497-y

Xia-qiu Wu, Jin Peng, Guo-qin Li, et al. Association between skin reactions and efficacy of summer acupoint application treatment on chronic pulmonary disease: A prospective study. [J]. Chinese Journal of Integrative Medicine 22(4):284-292(2016)
Wu, Xq., Peng, J., Li, Gq. et al. Association between skin reactions and efficacy of summer acupoint application treatment on chronic pulmonary disease: A prospective study., Chin. J. Integr. Med. 22, 284–292 (2016). https://doi.org/10.1007/s11655-016-2497-y DOI：

Xia-qiu Wu, Jin Peng, Guo-qin Li, et al. Association between skin reactions and efficacy of summer acupoint application treatment on chronic pulmonary disease: A prospective study. [J]. Chinese Journal of Integrative Medicine 22(4):284-292(2016) DOI： 10.1007/s11655-016-2497-y.

摘要

To examine the variations in the prevalence of skin reactions and the association between skin reactions and efficacy of summer acupoint application treatment (SAAT) on chronic pulmonary disease (CPD). A total of 2

038 patients with CPD were enrolled at 3 independent hospitals (defined as Groups A

B and C

respectively) in China. All patients were treated by SAAT

as applying a herbal paste onto the acupoints of Fengmen (BL 12) and Feishu (BL 13) on the dog days of summer

according to the lunar calendar

in 2008. Ten days after treatment

skin reaction data (no reaction

itching

stinging

blistering

and infection) were obtained via face-to-face interviews. Patients were retreated in the same hospital one year later

thereby allowing doctors to assess treatment efficacy based on the patients' symptoms

the severity of the spirometric abnormalities

and the concomitant medications used. A large number of patients (85.3%) displayed reactive symptoms; however

the marked associations between reactive symptoms and age or gender were not observed. An increased number of patients from Group B (99.3%) and Group C (76.5%) displayed reactive symptoms due to the increased mass of crude Semen Sinapis Albae. The effective rate of SAAT was as high as 90.4% for patients of Group B

which was followed by Group A (70.9%) and Group C (42.2%). Using stratified analyses

a convincing association between reactive symptoms and therapeutic efficacy was observed for patients with asthma [itching: odds ratio (OR)=2.17

95% confidence interval (CI): 1.49 to 3.14; blistering: OR=0.43

95% CI: 0.25 to 0.73; and no reaction: OR=0.56

95% CI: 0.35 to 0.90]. However

the same tendency was not observed for patients with chronic bronchitis and chronic obstructive pulmonary disease. SAAT can induce very mild skin reactions for patients with CPD

among which patients with asthma displayed a strong association between skin reactions and therapeutic efficacy. The skin reactions may be induced by the crude Semen Sinapis Albae.

Abstract

038 patients with CPD were enrolled at 3 independent hospitals (defined as Groups A

B and C

respectively) in China. All patients were treated by SAAT

as applying a herbal paste onto the acupoints of Fengmen (BL 12) and Feishu (BL 13) on the dog days of summer

according to the lunar calendar

in 2008. Ten days after treatment

skin reaction data (no reaction

itching

stinging

blistering

and infection) were obtained via face-to-face interviews. Patients were retreated in the same hospital one year later

thereby allowing doctors to assess treatment efficacy based on the patients' symptoms

the severity of the spirometric abnormalities

and the concomitant medications used. A large number of patients (85.3%) displayed reactive symptoms; however

which was followed by Group A (70.9%) and Group C (42.2%). Using stratified analyses

a convincing association between reactive symptoms and therapeutic efficacy was observed for patients with asthma [itching: odds ratio (OR)=2.17

95% confidence interval (CI): 1.49 to 3.14; blistering: OR=0.43

95% CI: 0.25 to 0.73; and no reaction: OR=0.56

95% CI: 0.35 to 0.90]. However

the same tendency was not observed for patients with chronic bronchitis and chronic obstructive pulmonary disease. SAAT can induce very mild skin reactions for patients with CPD

among which patients with asthma displayed a strong association between skin reactions and therapeutic efficacy. The skin reactions may be induced by the crude Semen Sinapis Albae.

关键词

summer acupoint application treatmentchronic pulmonary diseaseskin reactionChinese Medicinemoxibustion

Keywords

summer acupoint application treatmentchronic pulmonary diseaseskin reactionChinese Medicinemoxibustion

references

Wong GWK, Li ST, Hui DSC, Fok TF, Zhong NS, Chen YZ, et al. Individual allergens as risk factors for asthma and bronchial hyperresponsiveness in Chinese children. Eur Respirat J 2002;19:288–293.

Asthma Group, Chinese Thoracic Society. Guidelines for prevention and treatment of bronchial asthma. Chin J Asthma (Electronic Version, Chin) 2008;2:3–13.

Tai CJ, Chang CP, Huang CY, Chien LY. Effi cacy of Sanfujiu to treat allergies: patient outcomes at 1 year after treatment. Evid Based Complement Alternat Med 2007;4:241–246.

Tai CJ, Chien LY. The treatment of allergies using Sanfujiu: a method of applying Chinese herbal medicine paste to acupoints on three peak summer days. Am J Chin Med 2004;32:967–976.

WHO Regional Office for the Western Pacific. WHO international standard terminologies on traditional medicine in the Western Pacifi c Region. 2007:251. Available at: http://www.wpro.who.int/publications/PUB_9789290612483/en/

Jobst KA. Acupuncture in asthma and pulmonary disease: an analysis of effi cacy and safety. J Alternat Complement Med 1996;2:179–206.

Ngai SPC, Hui-Chan CWY, Jones AYM. A short review of acupuncture and bronchial asthma — Western and traditional Chinese medicine concepts. Hong Kong Physiother J 2006;24:28–38.

Lai XS, Li YM, Fan ZJ, Zhang JW, Liu BQ. An analysis of therapeutic effect of drug acupoint application in 209 cases of allergic asthma. J Tradit Chin Med 2001;21:122–126.

Li JS, Li SY, Yu XQ, Xie Y, Wang MH, Li ZG, et al. Bu-Fei Yi-Shen Granule combined with acupoint sticking therapy in patients with stable chronic obstructive pulmonary disease: a randomized, double-blind, double-dummy, active-controlled, 4-center study. J Ethnopharmacol 2012;141:584–591.

Peng J, Wu XQ, Hu JQ, Fang YG, Zi MJ, Liu BY. Influencing factors on efficacy of summer acupoint application treatment for allergic rhinitis: a retrospective study. J Tradit Chin Med 2012;32:377–381.

Kim JI, Choi JY, Lee H, Lee SM, Ernst E. Moxibustion for hypertension: a systematic review. BMC Cardiovasc Disord 2010;10:33.

Wen MS. Prevention and treatment for chronic pharyngitis by acupoint sticking therapy: a report of 100 cases. J Acupunct Tuina Sci 2012;10:254–257.

Endres HG, Molsberger A, Lungenhausen M, Trampisch HJ. An internal standard for verifying the accuracy of serious adverse event reporting: the example of an acupuncture study of 190,924 patients. Eur J Med Res 2004;9:545–551.

Park JE, Lee MS, Choi JY, Kim BY, Choi SM. Adverse events associated with acupuncture: a prospective survey. J Alternat Complement Med 2010;16:959–963.

Park JE, Lee SS, Lee MS, Choi SM, Ernst E. Adverse events of moxibustion: a systematic review. Complement Ther Med 2010;18:215–223.

Respiration Group, Chinese Pediatric Society, Chinese Medical Association. Guidelines for diagnosis, prevention and treatment of pediatric bronchial asthma. Chin J Pediatr (Chin) 2008;46:745–753.

Zheng XY, ed. Guiding principles of clinical research on new drugs of traditional Chinese medicine. Beijing: China Medical Science Press;2002:54.

COPD Group, Chinese Thoracic Society. Guidelines for diagnosis and treatment of chronic obstructive pulmonary disease. Continuing Med Educ (Chin) 2007;21:31–42.

Peng J, Wu XQ, He LY, Fang YG, Zi MJ, Yan SY, et al. Effects of summer acupoint application therapy in reducing exacerbation frequency of chronic lung diseases: protocol of a retrospective and prospective study. J Chin Integr Med (Chin) 2012;10:39–47.

Liu M, Kauh SK, Lim S. A study of direct moxibustion using mathematical methods. Comput Methods Biomechan Biomed Engin 2012;15:383–391.

Cao DX, Kitamura T, Todo H, Yoo SD, Sugibayashi K. Pretreatment effects of moxibustion on the skin permeation of FITC-dextran. International J Pharmaceut 2008;354:117–125.

Huang C, Sheu TWH. Study of the heat transfer effect in moxibustion practice. Developm Heat Transf 2011;9:557–572.

Wheeler J, Coppock B, Chen C. Does the burning of moxa (Artemisia vulgaris) in traditional Chinese medicine constitute a health hazard? Acupunct Med 2009;27:16–20.

Yi SH. Thermal properties of direct and indirect moxibustion. J Acupunct Merid Study 2009;2:273–279.

Liu LF, Liu T, Li GX, Wang Q, Ng T. Isolation and determination of p-hydroxgbenzoylcholine in tranditional Chinese medicine Semen Sinapis Albae. Analyt Bioanalyt Chem 2003;37:854–858.

Song XP, Ji XL. Study on vesicant characteristics of using Mylabris and Semen Sinapis Albae. Chin Acupunct Moibust (Chin) 2007;27:126–128.

Liu DL, Li SM. Impact on different processing methods for the concentration of Sinalbin in Semen Sinapis Albae. Chin J Tradit Chin Mater Med (Chin) 1990;15:28–29.

Zhang XM, Liu FL, Liang WB, Wang YQ, Xing FY, Zhang WE, et al. Antitussive, expectorant and antiasthmatic effects of Brassica alba extracts. Chin Tradit Herb Drugs (Chin) 2003;34:635–637.

Feng BM, Yu ZJ, Li F, Yang AG, Liu JY, Mu HM, et al. Study on the chemical constituents of Semen Sinapis Albae. J Dalian Univ (Chin) 2004;25:43–44.

Feng BM, Qiu L, Zhan QP, Wang GH, Shi LY, Jiang G, et al. Study on antitussive substance of Semen Sinapis Albae based on the relationship between drug processing and activity. Chin Pharmacol Bull (Chin) 2010;26:1173–1176.

Feng JT, Hu PC, Li XZ. Dorsal root ganglion: the target of acupuncture in the treatment of asthma. Adv Therapy 2007;24:598–602.

FULL TEXT LINK

More>

Views

Downloads

CSCD

Alert me when the article has been cited

Submit

Tools

Publicity Resources

Governor vessel moxibustion: Ancient Chinese medical technology with new vitality

Future view and development of immunology: Exploring the immunology based on Chinese medicine and culture

Cost-effectiveness analysis of combined Chinese medicine and Western medicine for ischemic stroke patients

Objective tongue inspection on 142 liver cancer patients with damp-heat syndrome

Effect of Ermiao Recipe (二妙方) with medicinal guide Angelicae Pubescentis Radix on promoting the homing of bone marrow stem cells to treat cartilage damage in osteoarthritis rats

Related Author

No data

Related Institution

Department of Acquired Immune Deficiency Syndrome Treatment and Research Center, the First Affiliated Hospital of Henan University of Traditional Chinese Medicine

Discipline of Nursing Science, the First Affiliated Hospital of Henan University of Traditional Chinese Medicine

Department of Cellular Immunology Lab, Key Laboraty of Virus Diseases Prevention and Treatment of Traditional Chinese Medicine of Henan Province

Georg-August-Universität Göttingen, Göttingen

The Key Laboratory of Geriatrics, Beijing Hospital and Beijing Institute of Geriatrics’ Ministry of Public Health

Address：1 Caochang, xiyuan, Beijing, People's Republic of China Postal code：100091
Tel：010-62886827, 62877592 Fax：010-62874291
Technical support is provided by Beijing Founder electronics co., LTD 京ICP备05067934号-1 京公网安备11010802024621
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰