Exploring traditional chinese medicine by a novel therapeutic concept of network target

Shao Li

doi:10.1007/s11655-016-2499-9

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Exploring traditional chinese medicine by a novel therapeutic concept of network target

Updated：2021-08-27

- Exploring traditional chinese medicine by a novel therapeutic concept of network target
- Chinese Journal of Integrative Medicine Vol. 22, Issue 9, Pages: 647-652(2016)
- Affiliations：
  
  Ministry of Education Key Laboratory of Bioinformatics and Bioinformatics Division, Tsinghua National Laboratory for Information Science and Technology/Department of Automation, Tsinghua University,Beijing,China
- Author bio：
- Funds：
  
  Supported by the National Natural Science Foundation of China (No. 81225025 and 91229201)
- DOI：10.1007/s11655-016-2499-9
  CLC：
- Published：2016，
  
  Published Online：4 May 2016，
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Li, S. Exploring traditional chinese medicine by a novel therapeutic concept of network target., Chin. J. Integr. Med. 22, 647–652 (2016). https://doi.org/10.1007/s11655-016-2499-9

Shao Li. Exploring traditional chinese medicine by a novel therapeutic concept of network target. [J]. Chinese Journal of Integrative Medicine 22(9):647-652(2016)
Li, S. Exploring traditional chinese medicine by a novel therapeutic concept of network target., Chin. J. Integr. Med. 22, 647–652 (2016). https://doi.org/10.1007/s11655-016-2499-9 DOI：

Shao Li. Exploring traditional chinese medicine by a novel therapeutic concept of network target. [J]. Chinese Journal of Integrative Medicine 22(9):647-652(2016) DOI： 10.1007/s11655-016-2499-9.

摘要

Traditional Chinese medicine (TCM) holds a holistic theory

and specializes in balancing disordered human body using numerous natural products

particularly Chinese herbal formulae. TCM has certain treatment advantages for patients suffering from various complex diseases. However

due to the complex nature of TCM

it remains difficult to unveil such holistic medicine by the current reductionism research strategies

which treat both herbal ingredients and targets in isolation. Recently

an emerging network pharmacology approach has been introduced to tackle this bottleneck problem. A TCM-derived novel therapeutic concept

"network target"

which is different from the Western medicine's "onetarget" concept

has been proposed from China. The network target strategy is able to illustrate the complex interactions among the biological systems

drugs

and complex diseases from a network perspective

and thus provides an innovative approach to access ancient remedies in a precision manner and at a systematic level

which also highlights TCM's potential in current medical systems.

Abstract

Traditional Chinese medicine (TCM) holds a holistic theory

and specializes in balancing disordered human body using numerous natural products

particularly Chinese herbal formulae. TCM has certain treatment advantages for patients suffering from various complex diseases. However

due to the complex nature of TCM

it remains difficult to unveil such holistic medicine by the current reductionism research strategies

which treat both herbal ingredients and targets in isolation. Recently

an emerging network pharmacology approach has been introduced to tackle this bottleneck problem. A TCM-derived novel therapeutic concept

"network target"

which is different from the Western medicine's "onetarget" concept

has been proposed from China. The network target strategy is able to illustrate the complex interactions among the biological systems

drugs

and complex diseases from a network perspective

and thus provides an innovative approach to access ancient remedies in a precision manner and at a systematic level

which also highlights TCM's potential in current medical systems.

关键词

Traditional Chinese Medicinenetwork targetnetwork pharmacologyHerbal Formulacomplex disease

Keywords

Traditional Chinese Medicinenetwork targetnetwork pharmacologyHerbal Formulacomplex disease

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