Objective:

2

To evaluate the effect of comprehensive therapy based on Chinese medicine (CM) patterns on self-efficacy and satisfaction with its effectiveness in patients with chronic obstructive pulmonary disease (COPD).

Methods:

2

A total of 216 patients were randomly divided into the trial group (

n

=108) and the control group (

n

=108) based on the stratified and block randomization design. Patients in the trial group were treated with conventional Western medicine combined with Bufei Jianpi Granules (补肺健脾颗粒)

Bufei Yishen Granules (补肺益肾颗粒)

and Yiqi Zishen Granules (益气滋肾颗粒) according to the CM patterns respectively

and patients in the control group were treated with conventional Western medicine. The COPD Self-Efficacy Scale (CSES) and the Effectiveness Satisfaction Questionnaire for COPD (ESQ-COPD) were employed in a 6-month treatment and in further 6 month follow-up visit.

Results:

2

Among the 216 patients

191 patients (97 in the trial group and 94 in the control group) fully completed the study. After 12-month treatment and follow-up

the mean scores of the trial group all continued to increase over time

which were significantly higher than those of the control group (

P

<

0.05)

and the improvement in the following trial group domain: negative affect domain (12.13%)

intense emotional arousal domain (12.21%)

physical exertion domain (11.72%)

weather/environmental domain (13.77%)

behavioral risk domain (7.67%) and total score (10.65%). The trial group also exhibited significantly higher mean scores in the ESQ-COPD (

P

<

0.05) and the improvement in the following domain: capacity for life and work domain (30.59%)

clinical symptoms domain (53.52%)

effect of therapy domain (35.95%)

convenience of therapy domain (35.54%)

and whole effect domain (52.47%).

Conclusions:

2

Bufei Jianpi Granules

Bufei Yishen Granules and Yiqi Zishen Granules can improve the self-efficacy and satisfaction of COPD patients.