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Conventional Acupuncture for Cardiac Arrhythmia: A Systematic Review of Randomized Controlled Trials
- Chinese Journal of Integrative Medicine Vol. 24, Issue 3, Pages: 218-226(2018)
- Affiliations：
1. Beijing University of Chinese Medicine,Beijing,China
2. Department of Cardiology, Dongfang Hospital, Beijing University of Chinese Medicine,Beijing,China
3. Beijing Institute of Traditional Chinese Medicine, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University,Beijing,China
4. Scientific Research Division, Dongfang Hospital, Beijing University of Chinese Medicine,Beijing,China
5. Intensive Care Unit, Dongfang Hospital, Beijing University of Chinese Medicine,Beijing,China
- Author bio：
- Funds：Supported by the National Natural Science Foundation of China (No. 81173176)
DOI：10.1007/s11655-017-2753-9
CLC：Published：2018，
Published Online：22 April 2017，
Scan for full text
Liu, J., Li, Sn., Liu, L. et al. Conventional Acupuncture for Cardiac Arrhythmia: A Systematic Review of Randomized Controlled Trials., Chin. J. Integr. Med. 24, 218–226 (2018). https://doi.org/10.1007/s11655-017-2753-9
Jing Liu, Si-nai Li, Lu Liu, et al. Conventional Acupuncture for Cardiac Arrhythmia: A Systematic Review of Randomized Controlled Trials. [J]. Chinese Journal of Integrative Medicine 24(3):218-226(2018)
Liu, J., Li, Sn., Liu, L. et al. Conventional Acupuncture for Cardiac Arrhythmia: A Systematic Review of Randomized Controlled Trials., Chin. J. Integr. Med. 24, 218–226 (2018). https://doi.org/10.1007/s11655-017-2753-9 DOI：
Jing Liu, Si-nai Li, Lu Liu, et al. Conventional Acupuncture for Cardiac Arrhythmia: A Systematic Review of Randomized Controlled Trials. [J]. Chinese Journal of Integrative Medicine 24(3):218-226(2018) DOI： 10.1007/s11655-017-2753-9.
摘要
To exam the effect and safety of conventional acupuncture (CA) on cardiac arrhythmia. Nine medical databases were searched until February 2016 for randomized controlled trials. Heterogeneity was measured by Cochran Q test. Meta-analysis was conducted if I2 was less than 85% and the characteristics of included trials were similar. Nine qualified studies involving 638 patients were included. Only 1 study had definitely low risk of bias
while 7 trials were rated as unclear and 1 as high. Meta-analysis of CA alone did not have a significant benefit on response rate compared to amiodarone in patients with atrial fibrillation (Af) and atrial flutter (AF) [relative risk (RR): 1.09; 95% confidence interval (CI): 0.79–1.49; P=0.61; I2=61%
P=0.11]. However
1 study with higher methodological quality detected a lower recurrence rate of Af in CA alone as compared with sham acupuncture plus no treatment
and benefits on ventricular rate and time of conversion to normal sinus rhythm were found in CA alone group by 1 study
as well as the response rate in CA plus deslanoside group by another study. Meta-analysis of CA plus anti-arrhythmia drug (AAD) was associated with a significant benefit on the response rate when compared with AAD alone in ventricular premature beat (VPB) patients (RR
1.19
95% CI: 1.05–1.34; P=0.005; I2=13%
P=0.32)
and an improvement in quality-of-life score (QOLS) of VPB also showed in 1 individual study. Besides
a lower heart rate was detected in the CA alone group by 1 individual study when compared with no treatment in sinus tachycardia patients (MD–21.84 [–27.21
–16.47]) and lower adverse events of CA alone were reported than amiodarone. CA may be a useful and safe alternative or additive approach to AADs for cardiac arrhythmia
especially in VPB and Af patients
which mainly based on a pooled estimate and result from 1 study with higher methodological quality. However
we could not reach a robust conclusion due to low quality of overall evidence.
Abstract
To exam the effect and safety of conventional acupuncture (CA) on cardiac arrhythmia. Nine medical databases were searched until February 2016 for randomized controlled trials. Heterogeneity was measured by Cochran Q test. Meta-analysis was conducted if I2 was less than 85% and the characteristics of included trials were similar. Nine qualified studies involving 638 patients were included. Only 1 study had definitely low risk of bias
while 7 trials were rated as unclear and 1 as high. Meta-analysis of CA alone did not have a significant benefit on response rate compared to amiodarone in patients with atrial fibrillation (Af) and atrial flutter (AF) [relative risk (RR): 1.09; 95% confidence interval (CI): 0.79–1.49; P=0.61; I2=61%
P=0.11]. However
1 study with higher methodological quality detected a lower recurrence rate of Af in CA alone as compared with sham acupuncture plus no treatment
and benefits on ventricular rate and time of conversion to normal sinus rhythm were found in CA alone group by 1 study
as well as the response rate in CA plus deslanoside group by another study. Meta-analysis of CA plus anti-arrhythmia drug (AAD) was associated with a significant benefit on the response rate when compared with AAD alone in ventricular premature beat (VPB) patients (RR
1.19
95% CI: 1.05–1.34; P=0.005; I2=13%
P=0.32)
and an improvement in quality-of-life score (QOLS) of VPB also showed in 1 individual study. Besides
a lower heart rate was detected in the CA alone group by 1 individual study when compared with no treatment in sinus tachycardia patients (MD–21.84 [–27.21
–16.47]) and lower adverse events of CA alone were reported than amiodarone. CA may be a useful and safe alternative or additive approach to AADs for cardiac arrhythmia
especially in VPB and Af patients
which mainly based on a pooled estimate and result from 1 study with higher methodological quality. However
we could not reach a robust conclusion due to low quality of overall evidence.
关键词
acupuncturecardiac arrhythmiasystematic review
Keywords
acupuncturecardiac arrhythmiasystematic review
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