Review of Anemone raddeana Rhizome and its pharmacological effects

Shu-ling Wang; Zhen-kun Zhao; Jian-feng Sun; Yun-ting Sun; Xiao-qing Pang; Zhao-wu Zeng; Tian Xie

doi:10.1007/s11655-017-2901-2

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Review of Anemone raddeana Rhizome and its pharmacological effects

Updated：2021-08-27

- Review of Anemone raddeana Rhizome and its pharmacological effects
- Chinese Journal of Integrative Medicine Vol. 24, Issue 1, Pages: 72-79(2018)
- Affiliations：
  
  1. Medical College, Hangzhou Normal University,Hangzhou,China
  2. Suzhou Dongrui Pharmaceutical Co., Ltd.,Suzhou,China
  3. Traditional Chinese Medicine College, Guangdong Pharmaceutical University,Guangzhou,China
  4. Department of Acupucture, Hangzhou Traditional Chinese Medicine Hospital,Hangzhou,China
- Author bio：
- Funds：
  
  Supported by the Natural Science Foundation of Zhejiang Province, China (No. LY16H270018)
- DOI：10.1007/s11655-017-2901-2
  CLC：
- Published：2018，
  
  Published Online：6 October 2017，
Scan for full text
Wang, Sl., Zhao, Zk., Sun, Jf. et al. Review of Anemone raddeana Rhizome and its pharmacological effects., Chin. J. Integr. Med. 24, 72–79 (2018). https://doi.org/10.1007/s11655-017-2901-2

Shu-ling Wang, Zhen-kun Zhao, Jian-feng Sun, et al. Review of Anemone raddeana Rhizome and its pharmacological effects. [J]. Chinese Journal of Integrative Medicine 24(1):72-79(2018)
Wang, Sl., Zhao, Zk., Sun, Jf. et al. Review of Anemone raddeana Rhizome and its pharmacological effects., Chin. J. Integr. Med. 24, 72–79 (2018). https://doi.org/10.1007/s11655-017-2901-2 DOI：

Shu-ling Wang, Zhen-kun Zhao, Jian-feng Sun, et al. Review of Anemone raddeana Rhizome and its pharmacological effects. [J]. Chinese Journal of Integrative Medicine 24(1):72-79(2018) DOI： 10.1007/s11655-017-2901-2.

摘要

The chemical compositions of Anemone raddeana Rhizome

a kind of traditional Chinese medicine

were reviewed

along with its bioactivity and pharmacological properties and method improvements of extracting and detecting triterpenoid saponins. A. raddeana Rhizome is used to treat neuralgia and rheumatism

and is rich in triterpenoid saponins

most of which are pentacyclic

with oleanane as the nucleus. So far

37 triterpenoid saponins have been determined from the herb. Its reported bioactivity and pharmacological properties have been described as anticancerous

antimicrobial

anti-inflammatory

analgesic

antipyretic

anticonvulsive

antihistaminic

and sedative. It has also been used for the induction of the humoral immune response and treatment of liver fibrosis in chronic hepatitis. However

the herb also has hemolytic effects and can be toxic

which limits its clinical application. Further studies are needed on the pharmaceutical functions

mechanisms

and immunological responses to contribute to the herb's clinical applications.

Abstract

The chemical compositions of Anemone raddeana Rhizome

a kind of traditional Chinese medicine

were reviewed

along with its bioactivity and pharmacological properties and method improvements of extracting and detecting triterpenoid saponins. A. raddeana Rhizome is used to treat neuralgia and rheumatism

and is rich in triterpenoid saponins

most of which are pentacyclic

with oleanane as the nucleus. So far

37 triterpenoid saponins have been determined from the herb. Its reported bioactivity and pharmacological properties have been described as anticancerous

antimicrobial

anti-inflammatory

analgesic

antipyretic

anticonvulsive

antihistaminic

and sedative. It has also been used for the induction of the humoral immune response and treatment of liver fibrosis in chronic hepatitis. However

the herb also has hemolytic effects and can be toxic

which limits its clinical application. Further studies are needed on the pharmaceutical functions

mechanisms

and immunological responses to contribute to the herb's clinical applications.

关键词

Anemone raddeana Rhizomephytochemical constituentpharmacological effectanticancerousantimicrobialanti-inflammatoryanalgesicChinese Medicine

Keywords

Anemone raddeana Rhizomephytochemical constituentpharmacological effectanticancerousantimicrobialanti-inflammatoryanalgesicChinese Medicine

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Georg-August-Universität Göttingen, Göttingen

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