Electroacupuncture Stimulation of Language-Implicated Acupoint Tongli (HT 5) in Healthy Subjects: An fMRI Evaluation Study

Lin-ling Li; Xiao-wu Liu; Fang Wu; Dong-chang Tong; Li-ping Ye; Hong-xing Tao; Peng Liu; Yun-hai Qiu; Wan-zhang Yang

doi:10.1007/s11655-017-2924-8

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Electroacupuncture Stimulation of Language-Implicated Acupoint Tongli (HT 5) in Healthy Subjects: An fMRI Evaluation Study

Updated：2021-08-27

- Electroacupuncture Stimulation of Language-Implicated Acupoint Tongli (HT 5) in Healthy Subjects: An fMRI Evaluation Study
- Chinese Journal of Integrative Medicine Vol. 24, Issue 11, Pages: 822-829(2018)
- Affiliations：
  
  1. Research Center for Neural Engineering, Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences,Shenzhen,China
  2. Department of Rehabilitation Medicine, the Sixth People’s Hospital in Shenzhen (Nanshan Hospital),Shenzhen,China
  3. Engineering Research Center of Molecular and Neuro Imaging Ministry of Education, School of Life Science and Technology, Xidian University,Xi’an,China
- Author bio：
- Funds：
  
  Supported by the Hundred Talents Program of Chinese Academy of Sciences (No. Y14408), Shenzhen Science and Technology Program (No. JC201005270293A, JC201104220257A and 201101017), and National Natural Science Foundation of China (No. 81471738)
- DOI：10.1007/s11655-017-2924-8
  CLC：
- Published：2018，
  
  Published Online：11 December 2017，
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Li, Ll., Liu, Xw., Wu, F. et al. Electroacupuncture Stimulation of Language-Implicated Acupoint Tongli (HT 5) in Healthy Subjects: An fMRI Evaluation Study., Chin. J. Integr. Med. 24, 822–829 (2018). https://doi.org/10.1007/s11655-017-2924-8

Lin-ling Li, Xiao-wu Liu, Fang Wu, et al. Electroacupuncture Stimulation of Language-Implicated Acupoint Tongli (HT 5) in Healthy Subjects: An fMRI Evaluation Study. [J]. Chinese Journal of Integrative Medicine 24(11):822-829(2018)
Li, Ll., Liu, Xw., Wu, F. et al. Electroacupuncture Stimulation of Language-Implicated Acupoint Tongli (HT 5) in Healthy Subjects: An fMRI Evaluation Study., Chin. J. Integr. Med. 24, 822–829 (2018). https://doi.org/10.1007/s11655-017-2924-8 DOI：

Lin-ling Li, Xiao-wu Liu, Fang Wu, et al. Electroacupuncture Stimulation of Language-Implicated Acupoint Tongli (HT 5) in Healthy Subjects: An fMRI Evaluation Study. [J]. Chinese Journal of Integrative Medicine 24(11):822-829(2018) DOI： 10.1007/s11655-017-2924-8.

摘要

To explore brain activations associated with electroacupuncture simulation at Tongli (HT 5) and its comparison with brain activations during picture-naming task. Twenty healthy subjects were enrolled in this study. Half of them received electroacupuncture stimulation at HT 5 (ACUP group) and the other half of them received stimulation at a nonmeridian sham acupoint (SHAM group). All subjects performed picture-naming task. Each subject finished two runs of functional magnetic resonance imaging examinations in one session and picture-naming task was performed before electroacupuncture stimulation. Subjective brain activations were obtained using generalized linear model and inter-group analyses were performed after that. The electroacupuncture stimulation at HT 5 induced significant brain activations in both the anterior and posterior language regions

including the left inferior frontal gyrus

which was in consistent with activations induced during picture-naming task. Group analysis showed a tendency of increased activation of ACUP group in left inferior frontal gyrus compared with SHAM group (P<0.05 FDR corrected). Electroacupuncture treatment at the acupoint HT 5 has modulation effect on typical language-implicated brain regions in healthy subjects

which provides supporting evidence for beneficial effects of needling at HT 5 for recovery of language function in aphasia.

Abstract

including the left inferior frontal gyrus

which provides supporting evidence for beneficial effects of needling at HT 5 for recovery of language function in aphasia.

关键词

electroacupunctureTongli (HT 5)functional magnetic resonance imaging

Keywords

electroacupunctureTongli (HT 5)functional magnetic resonance imaging

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