Understanding and Therapeutic Strategies of Chinese Medicine on Gut-Derived Uremic Toxins in Chronic Kidney Disease

Chuan Guo; Xiang-rong Rao

doi:10.1007/s11655-017-2926-6

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Understanding and Therapeutic Strategies of Chinese Medicine on Gut-Derived Uremic Toxins in Chronic Kidney Disease

Updated：2021-08-27

- Understanding and Therapeutic Strategies of Chinese Medicine on Gut-Derived Uremic Toxins in Chronic Kidney Disease
- Chinese Journal of Integrative Medicine Vol. 24, Issue 6, Pages: 403-405(2018)
- Affiliations：
  
  Department of Nephrology, Guang’anmen Hospital, China Academy of Chinese Medical Sciences,Beijing,China
- Author bio：
- Funds：
- DOI：10.1007/s11655-017-2926-6
  CLC：
- Published：2018，
  
  Published Online：11 May 2018，
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Guo, C., Rao, Xr. Understanding and Therapeutic Strategies of Chinese Medicine on Gut-Derived Uremic Toxins in Chronic Kidney Disease., Chin. J. Integr. Med. 24, 403–405 (2018). https://doi.org/10.1007/s11655-017-2926-6

Chuan Guo, Xiang-rong Rao. Understanding and Therapeutic Strategies of Chinese Medicine on Gut-Derived Uremic Toxins in Chronic Kidney Disease. [J]. Chinese Journal of Integrative Medicine 24(6):403-405(2018)
Guo, C., Rao, Xr. Understanding and Therapeutic Strategies of Chinese Medicine on Gut-Derived Uremic Toxins in Chronic Kidney Disease., Chin. J. Integr. Med. 24, 403–405 (2018). https://doi.org/10.1007/s11655-017-2926-6 DOI：

Chuan Guo, Xiang-rong Rao. Understanding and Therapeutic Strategies of Chinese Medicine on Gut-Derived Uremic Toxins in Chronic Kidney Disease. [J]. Chinese Journal of Integrative Medicine 24(6):403-405(2018) DOI： 10.1007/s11655-017-2926-6.

摘要

Chronic kidney disease (CKD) is a major disease that threatens human health. With the progression of CKD

the risk of cardiovascular death increases

which is associated with the elevated levels of uremic toxins (UTs). Representative toxins such as indoxyl sulfate and p-cresyl sulfate are involed in CKD progression and cardiovascular events inseparable from the key role of endothelial dysfunction. The therapeutic strategies of UTs are aimed at signaling pathways that target the levels and damage of toxins in modern medicine. There is a certain relevance between toxins and "turbid toxin" in the theory of Chinese medicine (CM). CM treatments have been demonstrated to reduce the damage of gut-derived toxins to the heart

kidney and blood vessels. Modern medicine still lacks evidence-based therapies

so it is necessary to explore the treatments of CM.

Abstract

Chronic kidney disease (CKD) is a major disease that threatens human health. With the progression of CKD

the risk of cardiovascular death increases

kidney and blood vessels. Modern medicine still lacks evidence-based therapies

so it is necessary to explore the treatments of CM.

关键词

chronic kidney diseaseuremic toxinstherapeutic strategiesChinese Medicine

Keywords

chronic kidney diseaseuremic toxinstherapeutic strategiesChinese Medicine

references

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Department of Nephrology, Guangdong Provincial Hospital of Chinese Medicine

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