Innovative Perspectives of Integrated Chinese Medicine on H. pylori

Hui Ye; Zong-ming Shi; Yao Chen; Jing Yu; Xue-zhi Zhang

doi:10.1007/s11655-017-2934-6

Your Location：

Home >

Browse articles >

Innovative Perspectives of Integrated Chinese Medicine on H. pylori

Updated：2021-08-27

- Innovative Perspectives of Integrated Chinese Medicine on H. pylori
- Chinese Journal of Integrative Medicine Vol. 24, Issue 11, Pages: 873-880(2018)
- Affiliations：
  
  1. Department of Traditional Chinese Medicine and Integrated Chinese Medicine, Peking University First Hospital,Beijing,China
  2. Department of Traditional Chinese Medicine, Peking University International Hospital,Beijing,China
- Author bio：
- Funds：
  
  Supported by the National Natural Science Foundation of China (No. 81473474), and Beijing Natural Science Foundation (No. 7172220)
- DOI：10.1007/s11655-017-2934-6
  CLC：
- Published：2018，
  
  Published Online：8 June 2018，
Scan for full text
Ye, H., Shi, Zm., Chen, Y. et al. Innovative Perspectives of Integrated Chinese Medicine on H. pylori., Chin. J. Integr. Med. 24, 873–880 (2018). https://doi.org/10.1007/s11655-017-2934-6

Hui Ye, Zong-ming Shi, Yao Chen, et al. Innovative Perspectives of Integrated Chinese Medicine on H. pylori. [J]. Chinese Journal of Integrative Medicine 24(11):873-880(2018)
Ye, H., Shi, Zm., Chen, Y. et al. Innovative Perspectives of Integrated Chinese Medicine on H. pylori., Chin. J. Integr. Med. 24, 873–880 (2018). https://doi.org/10.1007/s11655-017-2934-6 DOI：

Hui Ye, Zong-ming Shi, Yao Chen, et al. Innovative Perspectives of Integrated Chinese Medicine on H. pylori. [J]. Chinese Journal of Integrative Medicine 24(11):873-880(2018) DOI： 10.1007/s11655-017-2934-6.

摘要

Helicobacter pylori (H. pylori) treatment requires the development of more effective therapies

mainly owing to the challenges posed by the bacterial resistance to antibiotics. In China

critically high infection and antibiotic resistance rates have limited the application of classic H. pylori eradication therapies. Consequently

researchers are attempting to find new solutions by drawing from traditional medicine. This article reviews basic scientific and clinical progress in the use of integrated Chinese and Western medicine (IM) to treat H. pylori; describes the conflicting results between in vivo and in vitro studies in this regard; discusses the observed clinical effects of IM

with emphasis on traditional patent medicines; and proposes a role for IM in both the diagnosis and treatment of H. pylori

including the use of tongue manifestation as an early diagnostic method and capitalizing on IM’s direct and indirect methods for enhancing antibiotic effect.

Abstract

Helicobacter pylori (H. pylori) treatment requires the development of more effective therapies

mainly owing to the challenges posed by the bacterial resistance to antibiotics. In China

critically high infection and antibiotic resistance rates have limited the application of classic H. pylori eradication therapies. Consequently

with emphasis on traditional patent medicines; and proposes a role for IM in both the diagnosis and treatment of H. pylori

including the use of tongue manifestation as an early diagnostic method and capitalizing on IM’s direct and indirect methods for enhancing antibiotic effect.

关键词

Helicobacter pyloriintegrated traditional Chinese and Western medicinephytomedicine

Keywords

Helicobacter pyloriintegrated traditional Chinese and Western medicinephytomedicine

references

The Team of Collaboration of Helicobacter pylori research in China. Prevalence of Helicobacter pylori infection in China. Modern Dig Interv (Chin) 2010;15:265–270.

Song Z, Zhang J, He L, Chen M, Hou X, Li Z, et al. Prospective multi-region study on primary antibiotic resistance of Helicobacter pylori strains isolated from Chinese patients. Dig Liver Dis 2014;46:1077–1081.

Wang B, Lv ZF, Wang YH, Wang H, Liu XQ, Xie Y, et al. Standard triple therapy for Helicobacter pylori infection in China: a meta-analysis. World J Gastroenterol 2014;20:14973–14985.

Wu JY, Liou JM, Graham DY. Evidence-based recommendations for successful Helicobacter pylori treatment. Expert Rev Gastroenterol Hepatol 2014;8:21–28.

Vale FF, Oleastro M. Overview of the phytomedicine approaches against Helicobacter pylori. World J Gastroenterol 2014;20:5594–5609.

Liu WZ, Xie Y, Lv H, Cheng H, Zeng ZR, Zhou LY, et al. Fifth Chinese national consensus report on the management of Helicobacter pylori infection. Chin J Dig (Chin) 2017;36:364–378.

Wang XL, Jiao WL, Lu ZS. Preliminary screening of Chinese herbal medicine in inhibiting Helicobacter Pylori. Chin J Integr Tradit West Med (Chin) 1994;14:534–536.

Lien HM, Wang CY, Chang HY, Huang CL, Peng MT, Sing YT, et al. Bioevaluation of Anisomeles indica extracts and their inhibitory effects on Helicobacter pylori-mediated inflammation. J Ethnopharmacol 2013;145:397–401.

Xie JH, Chen YL, Wu QH, Wu J, Su JY, Cao HY, et al. Gastroprotective and anti-Helicobacter pylori potential of herbal formula Huangzhu Jianwei Recipe: safety and efficacy assessment. BMC Complement Altern Med 2013;13:119.

Liu W, Liu Y, Zhang XZ, Li N, Cheng H. In vitro bactericidal activity of Jinghua Weikang Capsule and its individual herb Chenopodium ambrosioides L. against antibiotic-resistant Helicobacter pylori. Chin J Integr Med 2013;19:54–57.

Ye H, Liu Y, Li N, Yu J, Cheng H, Li J, et al. Anti-Helicobacter pylori activities of Chenopodium ambrosioides L. in vitro and in vivo. World J Gastroenterol 2015;21:4178–4183.

Shang X, Tan Q, Liu R, Yu K, Li P, Zhao GP. In vitro anti-Helicobacter pylori effects of medicinal mushroom extracts, with special emphasis on the Lion’s Mane mushroom, Hericium erinaceus (higher Basidiomycetes). Int J Med Mushrooms 2013;15:165–174.

Zhang XQ, Gu HM, Li XZ, Xu ZN, Chen YS, Li Y. Anti-Helicobacter pylori compounds from the ethanol extracts of Geranium wilfordii. J Ethnopharmacol 2013;147:204–207.

Huang YQ, Huang GR, Wu MH, Tang HY, Huang ZS, Zhou XH, et al. Inhibitory effects of emodin, baicalin, schizandrin and berberine on hefA gene: treatment of Helicobacter pylori-induced multidrug resistance. World J Gastroenterol 2015;21:4225–4231.

Yu XD, Xie JH, Wang YH, Li YC, Mo ZZ, Zheng YF, et al. Selective antibacterial activity of patchouli alcohol against Helicobacter pylori based on inhibition of urease. Phytother Res 2015;29:67–72.

Feng J, Wang Y, Mo F, Zhagn S, Guo GM. Chemical constituents from ethyl acetate extracts of cortex dictamni and their anti-Helicobacter pylori activity in vitro. J Mountain Agricult and Biol (Chin) 2013;32:85–88.

Yang XT, Lin YH, Zhang JJ, Guo LK, Ge YL, Wang ZR. Antimicrobial activity against Helicobacter pylori of extracts from Liquorice. J Tongji Univ (Chin) 2013;34:26–30.

Lin J, Huang WW. A systematic review of treating Helicobacter pylori infection with traditional Chinese medicine. World J Gastroenterol 2009;15:4715–4719.

Wang TT, Zhang YM, Zhang XZ, Cheng H, Hu FL, Han HX, et al. Jinghuaweikang gelatin pearls plus proton pump inhibitor-based triple regimen in the treatment of chronic atrophic gastritis with Helicobacter pylori infection: a multicenter, randomized, controlled clinical study. Natl Med J China (Chin) 2013;93:3491–3495.

Hu FL, Cheng H, Zhang XZ, An HJ, Sheng JQ, Lu NH, et al. Jinghua Weikang Capsules combined with triple therapy in the treatment of Helicobacter pylori associated gastritis and duodenal ulcer and analysis of antibiotic resistance: a multicenter, randomized, controlled, clinical study. Natl Med J China (Chin) 2012;92:679–684.

Zhang YM, Wang TT, Ye H, Zhang XZ, Cheng H, Li JX, et al. Jinghua Weikang Capsules combined with triple therapy in the treatment of Helicobacter pylori associated gastritis: a multicenter, randomized, controlled clinical study. Chin J Integr Tradit West Med Dig (Chin) 2013;21:587–590.

Wenweishu/Yangweishu in the Treatment of Helicobacter pylori Positive Patients with Chronic Gastritis and Peptic Ulcer Study Group. A multicenter study of Chinese patent medicine Wenweishu/Yangweishu in the treatment of Helicobacter pylori positive patients with chronic gastritis and peptic ulcer. Natl Med J China (Chin) 2010;90:75–78.

Zhang JB, Zhao XD, Su Q, Liu Y, Gao SB, Liu DS, et al. Effect observation of Dongfangweiyao Capsule in treatment of Helicobacter pylori-associated gastritis. Med Pharm J Chin PLA (Chin) 2013;25:15–17.

Bai M, Kang F, Wang HL. Clinical observation on combination of traditional Chinese and Western medicine treatment of peptic ulcer. China J Chin Med (Chin) 2014;29:1220–1221.

Bharath TS, Reddy MS, Dhanapal R, Raj Kumar NG, Neeladri Raju P, Saraswathi T. Molecular detection and corelation of Helicobacter pylori in dental plaque and gastric biopsies of dyspeptic patients. J Oral Maxillofac Pathol 2014;18:19–24.

Zaric S, Bojic B, Popovic B, Milasin J. Eradication of gastric Helicobacter pylori ameliorates halitosis and tongue coating. J Contemp Dent Pract 2015;16:205–209.

Wang HH, Pan CH, Wu PP, Luo SF, Lin HJ, Wu CH. Alteration of the tongue manifestation reflects clinical outcomes of peptic ulcer disease. Altern Complement Med 2012;18:1038–1044.

Xie CE, Xue XX, Liu J, Han HX, Meng J, Zhang C. Analysis of relations between syndrome differentiation of Chinese medicine and tongue manifestation, Helicobacter pylori infection of epigastralgia. Chin J Tradit Chin Med Pharm (Chin) 2013;28:2287–2289.

Chen Y, Liu QY, Ye H, Zhang XZ, Cheng H, Xie SS, et al. Multicenter study on evolvement law of traditional Chinese medicine syndromes and syndrome factors of Helicobacter pylori related gastropathy. Modern China Clin Med (Chin) 2015;22:12–16.

De Francesco V, Zullo A, Perna F, Giorgio F, Hassan C, Vannella L, et al. Helicobacter pylori antibiotic resistance and [13C]urea breath test values. J Med Microbiol 2010;59:588–591.

Pan KF, Zhang L, Gerhard M, Ma JL, Liu WD, Ulm K, et al. A large randomised controlled intervention trial to prevent gastric cancer by eradication of Helicobacter pylori in Linqu County, China: baseline results and factors affecting the eradication. Gut 2016;65:9–18.

Feng SL, Zhao DM, Wang WL. The experience and reflection of the pre-treatment of Jinghua Weikang Capsules combined probiotics on Helicobacter pylori. World Chin Med (Chin) 2015;10 supple:18–20

Patel A, Shah N, Prajapati JB. Clinical application of probiotics in the treatment of Helicobacter pylori infection—a brief review. J Microbiol Immunol Infect 2014;47:429–437.

Ao MY, Wang MJ, Jiang SY, Xiong SQ, Li ZX, Wu QL, et al. Research progress on the effect of Chinese herbal medicine on intestinal probiotics. Chin J Microecol (Chin) 2011;23:475–478.

Houben MH, van de Beek D, Hensen EF, de Craen AJ, Rauws EA, Tytgat GN. A systematic review of Helicobacter pylori eradication therapy—the impact of antimicrobial resistance on eradication rates. Aliment Pharmacol Ther 1999;13:1047–1055.

FULL TEXT LINK

More>

Views

Downloads

CSCD

Alert me when the article has been cited

Submit

Tools

Publicity Resources

In vitro bactericidal activity of jinghua weikang capsule (荆花胃康胶丸) and its individual herb Chenopodium Ambrosioides L. against antibiotic-resistant Helicobacter Pylori

Effect of volatile oil of amomum on expressions of platelet activating factor and mastocarcinoma-related peptide in the gastric membrane of chronic gastritis patients with helicobacter-pylori infection

Clinical study on treatment of primary hepatocellular carcinoma by Shenqi mixture combined with microwave coagulation

Therapeutic evaluation on advanced pancreatic cancer Treated by Integrative Chinese and western medicine — Clinical analysis of 56 cases

Study on treatment of 313 patients with mid-late primary hepatocarcinoma by integrated traditional chinese and western medicine

Related Author

No data

Related Institution

Department of Gastroenterology, Peking University First Hospital

Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine

Department of Tradional Chinese Medicine and Integrated Tradional Chinese and Western Medicine, Peking University First Hospital

Xiangya Hospital of Central South University

Changsha Medical College

Address：1 Caochang, xiyuan, Beijing, People's Republic of China Postal code：100091
Tel：010-62886827, 62877592 Fax：010-62874291
Technical support is provided by Beijing Founder electronics co., LTD 京ICP备05067934号-1 京公网安备11010802024621
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰