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Research Progress on Reversing Multidrug Resistance in Tumors by Using Chinese Medicine
- Chinese Journal of Integrative Medicine Vol. 24, Issue 6, Pages: 474-480(2018)
- Affiliations：
1. Key Laboratory of Nanobiological Technology of Chinese Ministry of Health, Xiangya Hospital, Central South University,Changsha,China
2. School of Pharmacy, Central South University,Changsha,China
3. Department of Pharmacy, Tongren Hospital, Shanghai Jiaotong University, School of Medicine,Shanghai,China
4. Cancer Research Institute, Collaborative Innovation Center for Cancer Medicine, Key Laboratory for Carcinogenesis of Chinese Ministry of Health, School of Basic Medical Science, Central South University,Changsha,China
- Author bio：
- Funds：
DOI：10.1007/s11655-018-2910-1
CLC：Published：2018，
Published Online：2 June 2018，
Scan for full text
Zhao, Hd., Xie, Hj., Li, J. et al. Research Progress on Reversing Multidrug Resistance in Tumors by Using Chinese Medicine., Chin. J. Integr. Med. 24, 474–480 (2018). https://doi.org/10.1007/s11655-018-2910-1
Huan-dong Zhao, Hong-juan Xie, Jian Li, et al. Research Progress on Reversing Multidrug Resistance in Tumors by Using Chinese Medicine. [J]. Chinese Journal of Integrative Medicine 24(6):474-480(2018)
Zhao, Hd., Xie, Hj., Li, J. et al. Research Progress on Reversing Multidrug Resistance in Tumors by Using Chinese Medicine., Chin. J. Integr. Med. 24, 474–480 (2018). https://doi.org/10.1007/s11655-018-2910-1 DOI：
Huan-dong Zhao, Hong-juan Xie, Jian Li, et al. Research Progress on Reversing Multidrug Resistance in Tumors by Using Chinese Medicine. [J]. Chinese Journal of Integrative Medicine 24(6):474-480(2018) DOI： 10.1007/s11655-018-2910-1.
摘要
Multidrug resistance (MDR) is a major cause of cancer chemotherapy failure
and it is important to develop suitable reversal agents to overcome MDR. A majority of chemical reversal agents have acceptable reversal effects. However
the toxicity and adverse reactions associated with these agents restricts their clinical use. Chinese medicines (CMs) have lower toxicities and adverse reactions and are associated with multiple components
multiple targets and reduced toxicity. CMs have several advantages and could reverse MDR
decrease drug dosage
enhance patient compliance and increase efficacy. This review summarizes the current progress of CM reversal agents..
Abstract
Multidrug resistance (MDR) is a major cause of cancer chemotherapy failure
and it is important to develop suitable reversal agents to overcome MDR. A majority of chemical reversal agents have acceptable reversal effects. However
the toxicity and adverse reactions associated with these agents restricts their clinical use. Chinese medicines (CMs) have lower toxicities and adverse reactions and are associated with multiple components
multiple targets and reduced toxicity. CMs have several advantages and could reverse MDR
decrease drug dosage
enhance patient compliance and increase efficacy. This review summarizes the current progress of CM reversal agents..
关键词
tumormultidrug resistancereversal agentsChinese Medicine
Keywords
tumormultidrug resistancereversal agentsChinese Medicine
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