FOLLOWUS
Ethnopharmacological Potentials of
Warburgia ugandensis on Antimicrobial Activities- Chinese Journal of Integrative Medicine Vol. 27, Issue 8, Pages: 633-640(2021)
- Affiliations：
1.Korean Convergence Medicine Major, University of Science and Technology, Republic of Korea
2.Gombe Secondary School, P.O. Box 192, Butambala/Mpigi, Uganda
3.Herbal Medicine Research Division, Korea Institute of Oriental Medicine, Daejeon(34054), Republic of Korea
- Author bio：
Prof. Youngmin Kang, E-mail: ymkang@kiom.re.kr
- Funds：
DOI：10.1007/s11655-019-3042-6
CLC：Published：01 August 2021，
Published Online：17 December 2019，
Accepted：02 April 2019
Scan for full text
Denis Okello, Youngmin Kang. Ethnopharmacological Potentials of
Warburgia ugandensis on Antimicrobial Activities. [J]. Chinese Journal of Integrative Medicine 27(8):633-640(2021)Denis Okello, Youngmin Kang. Ethnopharmacological Potentials of
Warburgia ugandensis on Antimicrobial Activities. [J]. Chinese Journal of Integrative Medicine 27(8):633-640(2021) DOI： 10.1007/s11655-019-3042-6.
摘要
Abstract
Warburgia ugandensis
(
W. ugandensis
) is known by various names
including the East African greenheart
pepper bark tree
and Ugandan greenheart
and has a rich history of extensive use in the treatment of a host of human diseases in many African countries. This review is based on the botany and ethnopharmacological potentials of
W. ugandensis
for the treatment of pneumonia
asthma
malaria
candidiasis
skin infections
human immunodeficiency virus opportunistic infections
diarrhea
and measles given the common use in the management of these diseases. Extracts from
W. ugandensis
have strong antimicrobial activities against a broad spectrum of pathogens mainly because of the presence of abundant terpenoids
drimane
and coloratane type sesquditerpenoids amongst which are ugandensial
warburganal
mukaadial
and other secondary metabolites
such as tannins
flavonoids
saponins
steroids
and mannitol. This group of compounds gives the plant a high therapeutic value. Based on the review
there is a need for identification and isolation of the highly therapeutic phytochemical constituents and a drive for more preclinical and clinical trials to validate the safety and efficacy of the extracts. This gives basis for the potential development of new therapeutic drugs from the plant.
关键词
Keywords
Ethnopharmacological potentialWarburgia ugandensisgreenheartpharmacological activityreview
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