Essential Oil from <italic style="font-style: italic">Citrus aurantium</italic> Alleviates Anxiety of Patients Undergoing Coronary Angiography:A Single-Blind, Randomized Controlled Trial

Moradi Khalil; Ashtarian Hossein; Yakubu Danzima Nicholas; Saeedi Hamid; Bijan Behrouz; Akbari Farzaneh; Mehdi Mohammadi Mohammad

doi:10.1007/s11655-020-3266-5

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Essential Oil from Citrus aurantium Alleviates Anxiety of Patients Undergoing Coronary Angiography:A Single-Blind, Randomized Controlled Trial

Original Article | Updated：2021-08-16

- Essential Oil from Citrus aurantium Alleviates Anxiety of Patients Undergoing Coronary Angiography:A Single-Blind, Randomized Controlled Trial
- Chinese Journal of Integrative Medicine Vol. 27, Issue 3, Pages: 177-182(2021)
- Affiliations：
  
  1.Intensive Care Unit, Imam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran
  2.Health Education Department, Health School, Kermanshah University of Medical Sciences, Kermanshah, Iran
  3.School of Nursing and Midwifery, Tehran University of Medical Sciences, Tehran, Iran
  4.Student Research Committee, School of Nursing, Tabriz University of Medical Sciences, Tabriz, Iran
- Author bio：
  
  Correspondence to: Mr. Mohammad Mehdi Mohammadi, E-mail:mehdi20.mohamadi@gmail.com
- Funds：
- DOI：10.1007/s11655-020-3266-5
  CLC：
- Published：01 March 2021，
  
  Published Online：22 June 2020，
  
  Accepted：20 January 2020
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Moradi Khalil, Ashtarian Hossein, Yakubu Danzima Nicholas, et al. Essential Oil from Citrus aurantium Alleviates Anxiety of Patients Undergoing Coronary Angiography:A Single-Blind, Randomized Controlled Trial. [J]. Chinese Journal of Integrative Medicine 27(3):177-182(2021)
DOI：

Moradi Khalil, Ashtarian Hossein, Yakubu Danzima Nicholas, et al. Essential Oil from Citrus aurantium Alleviates Anxiety of Patients Undergoing Coronary Angiography:A Single-Blind, Randomized Controlled Trial. [J]. Chinese Journal of Integrative Medicine 27(3):177-182(2021) DOI： 10.1007/s11655-020-3266-5.

摘要

Abstract

Objective:

To determine the effectiveness and safety of essential oil from

Citrus aurantium

on anxiety in patients undergoing coronary angiography.

Methods:

A single-blind

randomized controlled trial was conducted in 80 patients experiencing coronary angiography in Imam Ali Hospital in Kermanshah

Iran from April to November in 2016. All patients were randomly divided into intervention and control groups by a random number table

40 cases in each group. The patients in the intervention group inhaled

Citrus aurantium

essential oil for 15–20 min about 60 min before angiography. Following the same procedure

distilled water was used instead of

Citrus aurantium

in the control group. Spielberger's State-Trait Anxiety Inventory (STAI) was filled in and vital signs including systolic blood pressure (SBP)

diastolic blood pressure (DBP)

respiratory and pulse rate were recorded before and 20 min after the intervention. Adverse reactions after intervention were observed.

Results:

In the intervention group

the mean scores of STAI

SBP

DBP

respiratory and pulse rate were 53.30±10.13

134.82±11.75 mm Hg

84.49±6.99 mm Hg

17.87±1.73 times/min

and 76.48±12.55 beats/min at baseline and significantly decreased to 42.37±10.15

124.49±10.48 mm Hg

79.23±6.62 mm Hg

14.54±1.43 times/min

and 70.03±13.66 beats/min respectively 20 min after intervention (all

0.05); however

in the control group

neither anxiety scores nor vital signs changed significantly (

0.05). All subjects reported no adverse reactions.

Conclusion:

Inhalation of the essential oil from

Citrus aurantium

was effective in reducing anxiety and stress levels in patients undergoing coronary angiography. Trial registration: IRCT2016040816797N2 (retrospectively registered on 21 April 2016

https://en.irct.ir/trial/15600)

关键词

Keywords

single-blindrandomized controlled trialessential oilCitrus aurantiumanxietycoronary angiographynon-drug treatmentaromatherapy

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Essential Oil from Citrus aurantium Alleviates Anxiety of Patients Undergoing Coronary Angiography:A Single-Blind, Randomized Controlled Trial

DOI：10.1007/s11655-020-3266-5

摘要

Abstract

关键词

Keywords

references