Primary Sjögren's syndrome (pSS) is a chronic autoimmune disease with a long duration of illness

for which there is no cure. Patients often suffer from anxiety and depression due to various reasons

exhibiting a decline in their quality of life. Chinese medicine (CM) has certain advantages in the treatment of pSS

which not only helps relieve clinical symptoms and improve treatment outcomes

but also reduces anxiety and depression and improves the quality of life. Therefore

CM should be considered as early as possible given its effectiveness and synergistic effects in treating pSS.