Kuanxiong Aerosol (宽胸气雾剂) in Treatment of Angina Pectoris: A Literature Review and Network Pharmacology

Yu-zhuo ZHANG; Rui-xiang ZENG; Yuan-shen ZHOU; Min-zhou ZHANG

doi:10.1007/s11655-021-2867-y

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Kuanxiong Aerosol (宽胸气雾剂) in Treatment of Angina Pectoris: A Literature Review and Network Pharmacology

Review | Updated：2021-09-01

- Kuanxiong Aerosol (宽胸气雾剂) in Treatment of Angina Pectoris: A Literature Review and Network Pharmacology
- Chinese Journal of Integrative Medicine Vol. 27, Issue 6, Pages: 470-480(2021)
- Affiliations：
  
  1.The Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou (510120), China
  2.Department of Critical Care Medicine, the Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou(510120), China
  3.Division of Chest Pain Center, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou (510120), China
- Author bio：
  
  Prof. ZHANG Min-zhou, E-mail:minzhouzhang@aliyun.com
- Funds：
- DOI：10.1007/s11655-021-2867-y
  CLC：
- Published：01 June 2021，
  
  Accepted：09 August 2020
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Yu-zhuo ZHANG, Rui-xiang ZENG, Yuan-shen ZHOU, et al. Kuanxiong Aerosol (宽胸气雾剂) in Treatment of Angina Pectoris: A Literature Review and Network Pharmacology. [J]. Chinese Journal of Integrative Medicine 27(6):470-480(2021)
DOI：

Yu-zhuo ZHANG, Rui-xiang ZENG, Yuan-shen ZHOU, et al. Kuanxiong Aerosol (宽胸气雾剂) in Treatment of Angina Pectoris: A Literature Review and Network Pharmacology. [J]. Chinese Journal of Integrative Medicine 27(6):470-480(2021) DOI： 10.1007/s11655-021-2867-y.

摘要

Abstract

Angina pectoris (AP) is the most common symptom of cardiovascular diseases

which seriously affects the quality of life in cardiovascular patients. Kuanxiong (KX) Aerosol (宽胸气雾剂)

a compound preparation that consists of 5 traditional Chinese medicines:

Herba Asari

Rhizoma Alpiniae Officinarum

Lignum Santali Albi

Fructus Piperis Longi

and Borneolum

has been used in the treatment of AP for many years

exhibiting a significant curative effect and less side-effect. For the convenience and comprehensive understanding of KX Aerosol

this review systematically summarizes evidence on KX Aerosol in the treatment of AP including the pharmacological effects of its composition

clinical research

animal experiments

and network pharmacology prediction. Meanwhile

we highlight the research limitation of KX Aerosol at present. This review may guide the clinical application of KX Aerosol and further provide a reference for the research of AP.

关键词

Keywords

Kuanxiong Aerosolangina pectorispharmacologyclinical applicationnetwork pharmacology

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