Monoclonal Gammopathy of Renal Significance (MGRS):Prospects for Treatment in Integrated Chinese and Western Medicine

Jin-pu LI; Ya-ting DU; Shen LI; Xiang-rong RAO

doi:10.1007/s11655-021-3446-y

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Monoclonal Gammopathy of Renal Significance (MGRS):Prospects for Treatment in Integrated Chinese and Western Medicine

Perspective | Updated：2021-09-01

- Monoclonal Gammopathy of Renal Significance (MGRS):Prospects for Treatment in Integrated Chinese and Western Medicine
- Chinese Journal of Integrative Medicine Vol. 27, Issue 9, Pages: 643-648(2021)
- Affiliations：
  
  Department of Nephrology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing(100053), China
- Author bio：
  
  Prof. RAO Xiang-rong, E-mail:raoyisheng@163.com
- Funds：
- DOI：10.1007/s11655-021-3446-y
  CLC：
- Published：01 September 2021，
  
  Published Online：08 June 2021，
  
  Accepted：22 March 2021
Scan for full text
Jin-pu LI, Ya-ting DU, Shen LI, et al. Monoclonal Gammopathy of Renal Significance (MGRS):Prospects for Treatment in Integrated Chinese and Western Medicine. [J]. Chinese Journal of Integrative Medicine 27(9):643-648(2021)
DOI：

Jin-pu LI, Ya-ting DU, Shen LI, et al. Monoclonal Gammopathy of Renal Significance (MGRS):Prospects for Treatment in Integrated Chinese and Western Medicine. [J]. Chinese Journal of Integrative Medicine 27(9):643-648(2021) DOI： 10.1007/s11655-021-3446-y.

摘要

Abstract

Monoclonal gammopathy of renal significance (MGRS) is a pathological state which presents with a spectrum of renal lesions. MGRS is characterized by pathogenic monoclonal immunoglobulins or light chains produced by a premalignant plasma cell or B cell clone. In view of inadequate understanding in the past

the low detection rate of MGRS often results in poor outcomes and reduces quality of life of patients. Thus

MGRS stands for a group of clinical refractory renal diseases. To date

no standard treatment strategy for MGRS is available. Current consensus suggests a clone-directed approach that aims to eradicate the offending clone

but its long-term prognosis is not clear. In this article

we discuss the diagnostic methods

highlight treatment advances

and introduce integrated Chinese and Western medicine in the management of MGRS.

关键词

Keywords

monoclonal gammopathy of renal significanceChinese medicineintegrative medicine

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Depar tment of Internal Medicine, Fuj ian Provincial Cardiovascular Disease Institute, the Shengli Clinical Medical College of Fujian Medical University

Department of Cardiology, Beijing Anzhen Hospital Affiliated to Capital Medical University—Beijing Institute of Heart, Lung and Blood Vessel Diseases

Center for Cardiovascular Diseases, Xiyuan Hospital, China Academy of Chinese Medical Sciences

Department of Cardiology, Beijing Chinese Medicine Hospital Affiliated to Capital Medical University

Department of Cardiology, Dongzhimen Hospital Affiliated to Beijing University of Traditional Chinese Medicine

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