Computational Medicine: Past, Present and Future

Lan-qing LYU; Hong-yan CUI; Ming-yi SHAO; Yu FU; Rui-xia ZHAO; Qiu-ping CHEN

doi:10.1007/s11655-021-3453-z

Your Location：

Home >

Browse articles >

Computational Medicine: Past, Present and Future

Interdisciplinary Knowledge | Updated：2022-06-27

- Computational Medicine: Past, Present and Future
- Chinese Journal of Integrative Medicine Vol. 28, Issue 5, Pages: 453-462(2022)
- Affiliations：
  
  The First Clinical Medical College of Henan University of Traditional Chinese Medicine, Zhengzhou (450003), China
- Author bio：
  
  Dr. SHAO Ming-yi, E-mail: shmy1016@163.com
- Funds：
- DOI：10.1007/s11655-021-3453-z
  CLC：
- Published：01 May 2022，
  
  Published Online：21 September 2021，
  
  Accepted：09 April 2021
Scan for full text
Lan-qing LYU, Hong-yan CUI, Ming-yi SHAO, et al. Computational Medicine: Past, Present and Future. [J]. Chinese Journal of Integrative Medicine 28(5):453-462(2022)
DOI：

Lan-qing LYU, Hong-yan CUI, Ming-yi SHAO, et al. Computational Medicine: Past, Present and Future. [J]. Chinese Journal of Integrative Medicine 28(5):453-462(2022) DOI： 10.1007/s11655-021-3453-z.

摘要

计算医学是一门利用计算机模型和复杂软件来模拟疾病的发展和治疗过程的新兴学科. 计算机硬件和软件技术的进步

特别是算法和图形处理单元 (GPUs) 的发展

使得计算机在医学领域的应用更加广泛和深入. 基于数学生物建模的计算机视觉方法将彻底改变医学临床研究和诊疗

其中一些生物模型已开始在各种研究中发挥出切实的作用. 本文从介绍计算医学的概念、特点等方面开始

然后回顾其发展史

并介绍了计算医学国内外研究进展

列举了一些计算医学的具体临床实际应用

讨论了计算医学在研发和应用中的关键问题和局限性

最后就其发展前景进行展望.

Abstract

Computational medicine is an emerging discipline that uses computer models and complex software to simulate the development and treatment of diseases. Advances in computer hardware and software technology

especially the development of algorithms and graphics processing units (GPUs)

have led to the broader application of computers in the medical field. Computer vision based on mathematical biological modelling will revolutionize clinical research and diagnosis

and promote the innovative development of Chinese medicine

some biological models have begun to play a practical role in various types of research. This paper introduces the concepts and characteristics of computational medicine and then reviews the developmental history of the field

including Digital Human in Chinese medicine. Additionally

this study introduces research progress in computational medicine around the world

lists some specific clinical applications of computational medicine

discusses the key problems and limitations of the research and the development and application of computational medicine

and ultimately looks forward to the developmental prospects

especially in the field of computational Chinese medicine.

关键词

Keywords

computational medicinemodelcomputational Chinese medicineartificial intelligencebig data

references

Zhao XY, Diao TX, Gao YH, Chen T, Kang D, Wang L.Interpretation and thinking of the American precision medicine program. Milit Med (Chin) 2015;39:241-244.

Wu HQ. Opportunities and challenges in the era of big data.Qiushi (Chin) 2013;20(4):47-49.

Tao XJ, Hu XF, Liu Y. Overview of big data research. J Syst Simul (Chin) 2013;25(S1):142-146.

Winslow RL, Trayanova N, Geman D, Miller MI.Computational medicine: translating models to clinical care.Sci Transl Med 2012;4:158rv11.

Li YP, Liu M. Evidence based medicine: clinical medicine in the 21st century. J Pract Med (Chin) 2000;16:517-520.

Yuan B. Towards state medicine: medical revolution initiated by precision medicine. Chin J Tradit Chin Med(Chin) 2017;32:1434-1448.

He JX, Sally LB, Xu J, Xu JM, Zhou XT, Zhang K.The practical implementation of artificial intelligence technologies in medicine. Nature Med 2019;25:30-36.

Goldsmith I, Evans PL, Goodrum H, Warbrick-Smith J,Bragg T. Chest wall reconstruction with an anatomically designed 3-D printed titanium ribs and hemi-sternum implant. 3D Print Med 2020;16(7):26.

Zhang SW. Who can handle big data can "carry the banner"—computational medicine is ready to emerge. Sci News (Chin) 2019;21(6):31-32.

Wang ZH. Computational medicine: facing the challenge of big data and transforming into clinical practice. J Bengbu Med Coll (Chin) 2014;39:1-2.

Lang YQ. Computational medicine: from model to clinical.Sci Res Inf Technol Appl (Chin) 2012;3(6):91-92.

Xiao F. Thinking from evidence-based medicine to precision medicine. Chin J Nephrol (Chin) 2014;3:123-128.

Mei T, Zhang Y, Hu S, Yang HM, Zhou Y. Construction of precision medicine system and its challenges. Chin Digit Med (Chin) 2016;11:44-48.

Ikopoulos P, Eaton C, eds. Understanding big data:analytics for enterprise class hadoop and streaming data.New York: McGraw-Hill Osborne Media; 2011.

Gautlieri M. Big data in 2013: what to expect. Inf Manag J 2013;47(2):20.

Qian K. Research on the application of data mining technology in medical big data. Indust Sci Technol Inninnov(Chin) 2020;2(10):56-58.

Fang SB, Yang B. Research status and prospect of digital human. Guangdong Med J (Chin) 2013;34:2585-2587.

Zhong SZ, ed. Digital human and digital anatomy. Jinan:Shandong Science and Technology Press;2004.

Lu YH, Ma XT, Zhang HX. Computational Chinese medicine and digital human body research. Dongguan: Proceedings of the National Symposium on Methodology of Traditional Chinese Medicine; 2008:89-92.

Shea KG, Grimm NL, Nichols FR, Jacobs JC Jr. Volumetric damage to the femoral physis during double-bundle posterio cruciate ligament reconstruction: a magnetic resonance imaging computer modeling study. Arthroscopy 2015;31:1102-1107.

Abdollahi S, Markvicka EJ, Majidi C, Feinberg AW. 3D printing silicone elastomer for patient-specific wearable pulse oximeter. Adv Healthcare Mater 2020;9:e1901735.

Zhu YI, Miller DL, Dou CY, Kripfgans OD. Characterization of macrolesions induced by myocardial cavitation-enabled therapy. IEEE Transact Biomed Eng 2015;62:717-727.

Lee JY, Bogyu C, Benjamin W, Min L. Customized biomimetic scaffolds created by indirect three-dimensional printingn for tissue engineering. Biofabrication 2013;5:045003.

Topol EJ. High-performance medicine: the convergence of human and artificial intelligence. Nature Med 2019;25:44-56.

Ngiam KY, Khor IW. Big data and machine learning algorithms for health-care delivery [published correction appears in Lancet Oncol 2019;20:293]. Lancet Oncol 2019;20:e262-e273.

Deo RC. Machine learning in medicine: will this time be different? Circulation 2020;142:1521-1523.

Miao FF, Liu JF. Development of artificial intelligence and its application prospect in medical field. Soft Sci Health 2009;23:222-224.

Handelman GS, Kok HK, Chandra RV, Razavi AH, Lee MJ, Asadi H. eDoctor: machine learning and the future of medicine. J Intern Med 2018;284:603-619.

Barrs RW, Jia J, Silver SE, Yost M, Mei Y. Biomaterials for bioprinting microvasculature. Chem Rev 2020;120:10887-10949.

Guo Y, Ren X, Chen YX, Wang TJ. Artificial intelligence meets Chinese medicine. Chin J Integr Med 2019;25:648-653.

Ferraro NM, Strober BJ, Einson J, Abell NS, Aguet F,Barbeira AN, et al. Transcriptomic signatures across human tissues identify functional rare genetic variation. Science 2020;369:eaaz5900.

More>

Views

Downloads

CSCD

Alert me when the article has been cited

Submit

Tools

Publicity Resources

Artificial Intelligence Meets Chinese Medicine

Related Author

No data

Related Institution

College of Acupuncture and Moxibustion, Fujian University of Traditional Chinese Medicine

Research Base of Traditional Chinese Medicine Syndrome, Fujian University of Traditional Chinese Medicine

Hangzhou Changgentang Clinic of Traditional Chinese Medicine

Department of Neurosurgery, Hamamatsu University School of Medicine, Handayama, Hamamatsu-city

Xiyuan Hospital, China Academy of Chinese Medicinal Sciences

Address：1 Caochang, xiyuan, Beijing, People's Republic of China Postal code：100091
Tel：010-62886827, 62877592 Fax：010-62874291
Technical support is provided by Beijing Founder electronics co., LTD 京ICP备05067934号-1 京公网安备11010802024621
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰