Prevalence and Factors Associated with Concomitant Chinese Medicine Use by Rheumatoid Arthritis Patients in A Multi-Ethnic Asian Population

You-yi HUANG; Xiao-hui XIN; Rehena Sultana; Julian Thumboo; Kok Yong FONG

doi:10.1007/s11655-021-3494-3

Your Location：

Home >

Browse articles >

Prevalence and Factors Associated with Concomitant Chinese Medicine Use by Rheumatoid Arthritis Patients in A Multi-Ethnic Asian Population

Original Article | Updated：2022-03-18

- Prevalence and Factors Associated with Concomitant Chinese Medicine Use by Rheumatoid Arthritis Patients in A Multi-Ethnic Asian Population
- Chinese Journal of Integrative Medicine Vol. 28, Issue 3, Pages: 223-228(2022)
- Affiliations：
  
  1.Duke-NUS Medical School, Singapore
  2.Department of Rheumatology and Immunology, Singapore General Hospital, Singapore
  3.Medicine Academic Clinical Program, Division of Medicine, Singapore General Hospital, Singapore
  4.Centre for Quantitative Medicine, Duke-NUS Medical School, Singapore
- Author bio：
  
  Prof. FONG Kok Yong, E-mail: fong.kok.yong@singhealth.com.sg
- Funds：
- DOI：10.1007/s11655-021-3494-3
  CLC：
- Published：01 March 2022，
  
  Published Online：28 July 2021，
  
  Accepted：15 June 2020
Scan for full text
You-yi HUANG, Xiao-hui XIN, Rehena Sultana, et al. Prevalence and Factors Associated with Concomitant Chinese Medicine Use by Rheumatoid Arthritis Patients in A Multi-Ethnic Asian Population. [J]. Chinese Journal of Integrative Medicine 28(3):223-228(2022)
DOI：

You-yi HUANG, Xiao-hui XIN, Rehena Sultana, et al. Prevalence and Factors Associated with Concomitant Chinese Medicine Use by Rheumatoid Arthritis Patients in A Multi-Ethnic Asian Population. [J]. Chinese Journal of Integrative Medicine 28(3):223-228(2022) DOI： 10.1007/s11655-021-3494-3.

摘要

Abstract

Objective:

To determine the prevalence

factors associated with and patterns of concomitant Chinese medicine (CM) with Western treatment use among patients with rheumatoid arthritis (RA) in a tertiary referral centre (Singapore General Hospital) in Singapore.

Methods:

We conducted a cross-sectional intervieweradministered survey of a consecutive sample of patients with RA in Singapore General Hospital centre regarding their CM use including data on patient demographics

disease characteristics

concomitant use of CM and reasons

concerns and disclosure patterns from March to August 2015. Univariate and multivariate logistic regression analyses were performed to determine the associations of CM use.

Results:

Prevalence of CM use among the 258 patients surveyed (male: female 42: 216; Chinese: Malay: Indian 191: 29: 34; mean age: 61 years; mean duration of RA: 10 years) was 46.1% (119/258). On multivariate analysis

Chinese ethnicity (OR

95% CI: 4.11

1.49–11.36)

Chinese speakers (OR

95% CI: 2.35

1.03–5.54)

middle-income group (OR

95% CI: 2.53

1.01–6.31) and greater learned helplessness (OR

95% CI: 1.13

1.04–1.22) were significantly associated with CM use. More CM users disclosed their CM use to CM physicians (87.3%

96/110)

sought advice from them on treatment interactions (59.4%

57/96) and how best to combine treatments (49.0%

47/96) than did so with rheumatologists (42.0%

50/119; 40.0%

20/50; and 42.0%

21/50

respectively). Forty-two percentage (29/69) of patients who concealed CM use from rheumatologists because their rheumatologists did not specifically enquire about CM use.

Conclusions:

Concomitant CM use among patients with RA treated in a tertiary referral centre in Singapore is high but voluntary disclosure is low. The associations identified can help doctors identify and enquire about CM use

minimizing potential adverse interactions.

关键词

Keywords

pevalencerheumatoid arthritisChinese medicinecomplementary therapies

references

Chandrashekara S. Complementary and alternative medicine in rheumatoid arthritis. Chin J Integr Med 2011;17:731-734.

Tan MG, Win MT, Khan SA. The use of complementary and alternative medicine in chronic pain patients in Singapore: a single-centre study. Ann Acad Med Sing 2013;42:133-137.

Su D, Li L. Trends in the use of complementary and alternative medicine in the United States: 2002–2007. J Health Care Poor Underserved 2011;22:296-310.

Seca S, Miranda D, Cardoso D, Nogueira B, Greten HJ,Cabrita A, et al. Effectiveness of acupuncture on pain,physical function and health-related quality of life in patients with rheumatoid arthritis: a systematic review of quantitative evidence. Chin J Integr Med 2019;25:704-709.

Tamhane A, McGwin G Jr, Redden DT, Hughes LB, Brown EE, Westfall AO, et al. Complementary and alternative medicine use in African Americans with rheumatoid arthritis.Arthritis Care Res (Hoboken) 2014;66:180-189.

Efthimiou P, Kukar M, Mackenzie CR. Complementary and alternative medicine in rheumatoid arthritis: no longer the last resort! HSS J 2010;6:108-111.

Tokem Y, Parlar Kilic S, Ozer S, Nakas D, Argon G. A multicenter analysis of the use of complementary and alternative medicine in Turkish patients with rheumatoid arthritis: holistic nursing practice review copy. Holist Nurs Pract 2014;28:98-105.

Lee MS, Yang CY, Lee SI, Joo MC, Shin BC, Yoo WH, et al.Use of complementary and alternative medicine by rheumatoid arthritis patients in Korea. Clin Rheumatol 2008;27:29-33.

Lim MK, Sadarangani P, Chan HL, Heng JY.Complementary and alternative medicine use in multiracial Singapore. Complement Ther Med 2005;13:16-24.

Leong KP, Pong LY, Chan SP. Why lupus patients use alternative medicine? Lupus 2003;12:659-664.

Zhang P, Li J, Han Y, Yu XW, Qin L. Traditional Chinese medicine in the treatment of rheumatoid arthritis: a general review. Rheumatol Int 2010;30:713-718.

Alaaeddine N, Okais J, Ballane L, Baddoura RM. Use of complementary and alternative therapy among patients with rheumatoid arthritis and osteoarthritis. J Clin Nurs 2012;21:3198-3204.

National Institutes of Health. Acupuncture. NIH consensus statement online. United States, 3–5 Nov, 1997. National Institutes of Health. 1997;15:1-34.

Schmier JK, Halpern MT. Patient recall and recall bias of health state and health status. Expert Rev Pharmacoecon Outcomes Res 2004;4:159-163.

Brady TJ. Measures of self-efficacy, helplessness,mastery, and control: The Arthritis Helplessness Index(AHI)/Rheumatology Attitudes Index (RAI), Arthritis Self-Efficacy Scale (ASES), Children's Arthritis Self-Efficacy Scale (CASE), Generalized Self-Efficacy Scale(GSES), Mastery Scale, Multi-Dimensional Health Locus of Control Scale (MHLC), Parent's Arthritis Self-Efficacy Scale (PASE), Rheumatoid Arthritis Self-Efficacy Scale(RASE), and Self-Efficacy Scale (SES). Arthritis Care Res 2003;49:S147-S164.

Thumboo J, Fong KY, Chan SP, Leong KH, Feng PH,Thio ST, et al. The Rheumatology Attitudes Index and its helplessness subscale are valid and reliable measures of learned helplessness in Asian patients with systemic lupus erythematosus. J Rheumatol 1999;26:1512-1517.

Key household income trends, 2014. 2015. Accessed September 22, 2015. Available from: http://www.singstat.gov.sg/docs/default-source/default-document-library/publications/publications_and_papers/household_income_and_expenditure/pp-s21.pdfhttp://www.singstat.gov.sg/docs/default-source/default-document-library/publications/publications_and_papers/household_income_and_expenditure/pp-s21.pdf.

Public housing in Singapore: examining fundamental shifts. 2014. Accessed September 22, 2014. Available from: https://lkyspp.nus.edu.sg/wp-content/uploads/2014/11/Public-Housing-in-Singapore.pdfhttps://lkyspp.nus.edu.sg/wp-content/uploads/2014/11/Public-Housing-in-Singapore.pdf.

Sato A. Does socio-economic status explain use of modern and traditional health care services? Soc Sci Med 2012;75:1450-1459.

Jacobs JWG, Kraaimaat FW, Bijlsma JW. Why do patients with rheumatoid arthritis use alternative treatments? Clin Rheumatol 2001;20:192-196.

la Cour P. Rheumatic disease and complementary-alternative treatments: a qualitative study of patient's experiences. J Clin Rheumatol 2008;14:332-337.

Jong MC, van de Vijver L, Busch M, Fritsma J, Seldenrijk R. Integration of complementary and alternative medicine in primary care: what do patients want? Patient Educ Couns 2012;89:417-422.

More>

Views

Downloads

CSCD

Alert me when the article has been cited

Submit

Tools

Publicity Resources

Inokosterone Is a Potential Drug Target of Estrogen Receptor 1 in Rheumatoid Arthritis Patients:Analysis from Active Ingredient of Cyathula Officinalis

Chinese Herbal Formula Ermiao Powder (二妙散) Regulates Cholinergic Anti-inflammatory Pathway in Rats with Rheumatoid Arthritis

Chemical Composition, Pharmacological Effects and Clinical Applications of Cinobufacini

Immunomodulatory Function of Pien Tze Huang in T Cell-Mediated Anti-tumor Activity against B16-F10, MC38 and Hep1-6 Tumor Models

Safflower Yellow Inhibits Progression of Hepatocellular Carcinoma by Modulating Immunological Tolerance via FAK Pathway

Related Author

No data

Related Institution

Department of Medical Laboratory, Luoyang Orthopedic Hospital of Henan Province, Orthopedic Institute of Henan Province

Miller School of Medicine, University of Miami

Institute of Technical Biology & Agriculture Engineering,Hefei Institutes of Physical Science, Chinese Academy of Sciences

Eatobe Pte

College of Basic Medical Sciences, Shanxi University of Chinese Medicine

Address：1 Caochang, xiyuan, Beijing, People's Republic of China Postal code：100091
Tel：010-62886827, 62877592 Fax：010-62874291
Technical support is provided by Beijing Founder electronics co., LTD 京ICP备05067934号-1 京公网安备11010802024621
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰