<italic style="font-style: italic">Cistanche Deserticola</italic> for Regulation of Bone Metabolism:Therapeutic Potential and Molecular Mechanisms on Postmenopausal Osteoporosis

WANG Cheng; LI Feng; LI Yang; FENG Hui; ZHAO Min-wei; TU Peng-fei; TIAN Hua

doi:10.1007/s11655-022-3518-z

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Cistanche Deserticola for Regulation of Bone Metabolism:Therapeutic Potential and Molecular Mechanisms on Postmenopausal Osteoporosis

Herbal and Botanical Review | Updated：2023-01-05

- Cistanche Deserticola for Regulation of Bone Metabolism:Therapeutic Potential and Molecular Mechanisms on Postmenopausal Osteoporosis
- Chinese Journal of Integrative Medicine Vol. 29, Issue 1, Pages: 74-80(2023)
- Affiliations：
  
  1.Department of Orthopaedics/Engineering Research Center of Bone and Joint Precision Medicine/Beijing Key Laboratory of Spinal Disease Research, Peking University Third Hospital,Beijing (100191), China
  2.Peking University School of Pharmaceutical Sciences, Beijing (100191), China
- Author bio：
  
  Prof. TIAN Hua, E-mail: tianhua@bjmu.edu.cn
- Funds：
- DOI：10.1007/s11655-022-3518-z
  CLC：
- Published：01 January 2023，
  
  Published Online：05 August 2022，
  
  Accepted：30 December 2021
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WANG Cheng, LI Feng, LI Yang, et al. Cistanche Deserticola for Regulation of Bone Metabolism:Therapeutic Potential and Molecular Mechanisms on Postmenopausal Osteoporosis. [J]. Chinese Journal of Integrative Medicine 29(1):74-80(2023)
DOI：

WANG Cheng, LI Feng, LI Yang, et al. Cistanche Deserticola for Regulation of Bone Metabolism:Therapeutic Potential and Molecular Mechanisms on Postmenopausal Osteoporosis. [J]. Chinese Journal of Integrative Medicine 29(1):74-80(2023) DOI： 10.1007/s11655-022-3518-z.

摘要

Abstract

Osteoporosis is a generalized disease of bone that leads to a loss of bone density and bone mass

destruction of bone microstructure

increased brittleness and therefore fracture. At present

the main treatment of Western medicine is drug therapy such as bisphosphonates

calcitriol

vitamin D

etc. However

long-term use of these drugs may bring some adverse reactions. Chinese herbal medicine

Cistanche deserticola

could regulate bone metabolism by promoting osteoblast activity and inhibiting osteoclast activity with low toxicity and adverse reactions. Therefore

Cistanche deserticola

has attracted increasing attention for its efficacy in the prevention and treatment of osteoporosis in recent years. Here we present a literature review of the molecular pathways involved in osteoporosis and the effects of

Cistanche deserticola

on bone metabolism. Our objective is to clarify the mechanism of

Cistanche deserticola

in the treatment of osteoporosis.

关键词

Keywords

osteoporosisCistanche deserticolabone metabolismChinese medicine

references

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Related Institution

Department of Integrated Traditional Chinese and Western Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Faculty of Medicine and Life Science, Xiamen University

Fujian Pien Tze Huang Enterprise Key Laboratory of Natural Medicine Research and Development

Good Clinical Practice Development, Guangdong Provincial Key Laboratory of Bone and Joint Degeneration Diseases, The Third Affiliated Hospital of Southern Medical University

Department of Pharmacy, Sun Yat-sen Memorial Hospital, Sun Yat-sen University

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⁰

Cistanche Deserticola for Regulation of Bone Metabolism:Therapeutic Potential and Molecular Mechanisms on Postmenopausal Osteoporosis

DOI：10.1007/s11655-022-3518-z

摘要

Abstract

关键词

Keywords

references