Objective:

2

To analyze Chinese medicine (CM) prescriptions for gastroesophageal reflux disease (GERD)

we model topics on GERD-related classical CM literature

providing insights into the potential treatment.

Methods:

2

Clinical guidelines were used to identify symptom terms for GERD

and CM literature from the database "Imedbooks" was retrieved for related prescriptions and their corresponding sources

indications

and other information. BERTopic was applied to identify the main topics and visualize the data.

Results:

2

A total of 36

207 entries are queried and 1

938 valid entries were acquired after manually filtering. Eight topics were identified by BERTopic

including digestion function abate

stomach flu

respiratory-related symptoms

gastric dysfunction

regurgitation and gastrointestinal dysfunction in pediatric patients

vomiting

stroke and alcohol accumulation are associated with the risk of GERD

vomiting and its causes

regurgitation

epigastric pain

and symptoms of heartburn.

Conclusions:

2

Topic modeling provides an unbiased analysis of classical CM literature on GERD in a time-efficient and scale-efficient manner. Based on this analysis

we present a range of treatment options for relieving symptoms

including herbal remedies and non-pharmacological interventions such as acupuncture and dietary therapy.