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      Vol. 4 ， Issue 4 ， 1998
      • Lin Qiucheng
        Vol. 4, Issue 4, Pages: 242-246(1998) DOI: 10.1007/BF02935463
        Keywords：Traditional Chinese Medicine;Western Medicine;Blood Stasis Syndrome;Fungiform Papilla;Lingual Epithelium   
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        Published：2021-08-27
      • Shen Di,Shen Lin,Wang Ailian,Liu Zhongping,Yang Rui,Wei Wenning,Yang Yan
        Vol. 4, Issue 4, Pages: 247-250(1998) DOI: 10.1007/BF02935464
        Abstract：Objective: To explore the effect and pharmacological mechanism of Xiaoyu Zhixue Tablet (XZT).Methods: XZT mainly composed of Chinese medical herbs to replenish Qi and remove stasis was used to treat patients with idiopathic multifocal bleeding and platelet aggregation defect. Patients were divided into 2 groups, the TCM group (104 cases) treated with XZT, and the control group (84 cases) with vitamin C, K and P, adrenosin and/or artificial menstruation, for at least 4 months.Results: The hemostatic effective rate was 92.3% in the TCM group and 27.4% in the control group (P< 0.005), the recovery rate of platelet aggregation after 6 months’ therapy was 69.2% and only 1.8% respectively. The difference between the two groups was very significant (P < 0.005).Conclusion: XZT could regulate the hemostatic action and platelet aggregation  
        Keywords：multifocal bleeding;platelet aggregation defect;Xiaoyu Zhixue Tablet   
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        Published：2021-08-27
      • Zhang Yanzhou,Liu Dongxu,Li Yushu,Feng Yibo,Mao Huanyuan
        Vol. 4, Issue 4, Pages: 250(1998) DOI: 10.1007/BF02935465
        Keywords：Thrombin;Platelet Aggregation;Blood Coagulation;Mitral Stenosis;Platelet Aggrega   
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        Published：2021-08-27
      • Su Eryun,Chen Huishu
        Vol. 4, Issue 4, Pages: 251-254(1998) DOI: 10.1007/BF02935466
        Abstract：Objective: To investigate the pharmaceutical effect of Spatholobus suberectus composita (SSC) on bone marrow hematopoiesis and microenvironment of aplastic anemia.Methods: One hundred and six cases of aplastic anemia patients were treated by SSC for 24 months, and the pathological changes of bone marrow of 45 patients were observed before and after treatment, and compared with those of 17 cases of normal volunteers as control.Results: The total effective rate was 77.4%. The volume of nucleated cells changed from 15.7 ± 10.2 vol % to 39.2 ± 13.9 vol%, the percentage of the granulocytes from 31.4 ± 12.4 % to 39.9 ± 10.4%), the erythroblasts from 19.8 ± 15.9% to 36.7 ± 13.5%, megakaryocytes from 1.4 ± 2.3 cell/section to 24.0 ± 24. 6 cell/section), and the microvessel number from 40.0 ± 23.4 ves/100mm2 to 201.0 ± 141.0 ves/100mm2), all the criteria increased significantly (P < 0.01 orP < 0. 05).Conclusion: SSC could not only irritate the hematopoiesis, but also exert reconstructive action to marrow microenvironment.  
        Keywords：aplastic anemia;Spatholobus suberectus composita;pathology of bone marrow   
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        Published：2021-08-27
      • Zhao Qi,Cui Naiqiang,Li Jikun,Wu Xianzhong
        Vol. 4, Issue 4, Pages: 254(1998) DOI: 10.1007/BF02935467
        Keywords：Ceru;aplastic anemia;acute leukemia;Multiple Organ Dysfunction Syndrome;Reticulin   
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        Published：2021-08-27
      • Yan Fengshu,Li Guibin,Li Fengxue,Zhu Aiying,Yu Minzhi,Zhang Aihua
        Vol. 4, Issue 4, Pages: 255-258(1998) DOI: 10.1007/BF02935468
        Abstract：Objective: To find the effective method in treating infantile chronic aplastic anemia (ICAA) by using traditional Chinese medicine (TCM).Methods: Seventy-eight cases of ICAA were observed, 48 in the treated group were treated with Tiaoxue Yisui recipe, and 30 cases in the control group with SSL regimen.Results: The remission rate and total effective rate in the treated group were 52.08% and 81.25% respectively, which were higher than those in the control group (P < 0.05). After one year’s treatment the ratio of hemopoietic and non-hemopoietic cells in the treated group was higher than that in the control group (P < 0.05).Conclusion: Tiaoxue Yisui recipe could improve the living quality of ICAA patients. The therapeutical mechanism of the recipe might be related to its promoting the proliferation of hemopoietic stem cells and regulating the immune function.  
        Keywords：infantile chronic aplastic anemia;Tiaoxue Yisui recipe;hemopoietic stem cell;immunoregulation   
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        Published：2021-08-27
      • Yin Chunlin,Xu Chengbin
        Vol. 4, Issue 4, Pages: 258(1998) DOI: 10.1007/BF02935469
        Keywords：Vascular Smooth Muscle Cell;Iliac Artery;aplastic anemia;Emodin;Intimal Hyperplasia   
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        Published：2021-08-27
      • Ma Rou,Liu Feng,Yang Jingmin,Ma Ling,Xu Yonggang,Hu Naiping,Hu Xiaomei,Xue Xiangjun,Li Liu,Wang Nan
        Vol. 4, Issue 4, Pages: 259-262(1998) DOI: 10.1007/BF02935470
        Abstract：Objective: To observe the effect of Fuzheng Kangbai Granule (FZKBG) on long-term survival of patients with acute leukemia, and to study its mechanism in treating minimal residual leukemia.Methods: FZKBG was used to treat 90 cases of completely remitted acute leukemia to observe the effect of treatment on 5-year event free interval (EFI), over survival (OS) and the immune function of patients.Results: Five-year EFI and OS of the 90 cases were 62.4% and 77.2% respectively, and the immune functions after FZKBG therapy were improved significantly.Conclusion: FZKBG could increase the 5-year EFI and 5-year OS, which might be reached through improving immune function of patients.  
        Keywords：Fuzhen Kangbai Granule;acute leukemia;quality of life span;immune function   
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        Published：2021-08-27
      • Tan Huo,Ying Hongguang,Chu Jianxin
        Vol. 4, Issue 4, Pages: 262(1998) DOI: 10.1007/BF02935471
        Keywords：Leukemia;Leukemia Cell;Acute Myelogenous Leukemia;HL60 Cell Line;Augmented Effect   
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        Published：2021-08-27
      • Yin Guangyao,He Xuefen,Yin Yufen,Li Baofu,Yang Zhongren
        Vol. 4, Issue 4, Pages: 263-266(1998) DOI: 10.1007/BF02935472
        Abstract：Objective: To evaluate the effect of Zhuchun pill (ZCP) on senile Kidney-Yang Deficiency (KYD).Methods: By single blind method, 45 elderly males with KYD were divided randomly into the ZCP group (treated by ZCP) and the control group (treated by placebo, starch capsule) and treated for 3 months.Results: ZCP could greatly improve the main symptoms of KYD,P < 0. 01 in comparison with the control group. After treatment, in the ZCP group, the3H-TdR lymphocyte transformation rate, levels of serum C3, IgA, IgD, IgG and IgM, superoxide dismutase, plasma adrenocortical hormone, testosterone and cyclic adenosine monophosphate all increased,P < 0.01, and plasma lipid peroxide decreased,P < 0.01. While in the control group, no remarkable change was found in these parameters.Conclusion: ZCP could improve the KYD through regulating the immunity, endocrine function and scavenging the free radicals in organism.  
        Keywords：Kidney Yang Deficiency;Zhuchun Pill;immunity;endocrine hormone;lipid peroxide;superoxide dismutase   
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        Published：2021-08-27
      • Huang Ruijian,Liao Chongxian,Chen Daozhong,Chen Weimin,Weng Qinyong
        Vol. 4, Issue 4, Pages: 266(1998) DOI: 10.1007/BF02935473
        Keywords：Pulmonary Hypertension;Congenital Heart Disease;PGI2;Pulmonary Hypertension Patient;Compensation Function   
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        Published：2021-08-27
      • Cai Depei,Ji Zhiying,Shi Yumin
        Vol. 4, Issue 4, Pages: 267-271(1998) DOI: 10.1007/BF02935474
        Abstract：Objective: To find effective therapeutic approach for treating true idiopathic precocious puberty suitable to our national condition and different from gonadotrophin releasing hormone analogue.Methods: One hundred and six girls with idiopathic precocious puberty were divided into 3 groups. The 51 girls in the TCM-WM group were treated with Chinese herbal medicine combined with megestrol acetate (MA), 35 girls in the MA group treated with megestrol acetate alone, and 20 girls were taken as control group and given no treatment at all. Luteinizing hormone releasing hormone (LHRH) stimulating test were performed before and after treatment, and the size of the uterus and ovary, linear growth rate, X-ray bone age measurement and final height prediction were also observed simultaneously.Results: After treated with TCM-WM for 2.7 years in average, the luteinizing hormone (LH) peak value of LHRH stimulating test was reduced from 48.5 ± 5.2 IU/L to 12. 2 ± 1.3 IU/L, size of uterus and ovary decreased, secondary sexual characteristics regressed, the bone age difference/chronological age difference value (ΔBA/ΔCA) reduced from 1.35 ± 0.09 to 0.65 ± 0.05 and predictive final height increased from 153.3 ± 0.5 cm to 158.5 ± 0.6 cm.Conclusion: TCM-WM therapy could not only modulate the function of hypothalamic-pituitary-ovarian axis and the development of internal genitalia, but also could decelerate skeletal growth, delay skeletal maturation, and thereby prevent premature epiphyseal fusion and increase the final height of patients.  
        Keywords：precocious puberty;Traditional Chinese Medicine;Megestrol;skeletal development;hypothalamic-pituitary-ovarian axis   
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        Published：2021-08-27
      • Xiao Yuguang,Tang Pei
        Vol. 4, Issue 4, Pages: 272-274(1998) DOI: 10.1007/BF02935475
        Abstract：Objective: To study the effect of Dachengqi Decoction in Treating diabetic gastric retention.Methods: Twenty Patients of diabetic gastric retention were treated with Dachengqi Decoction with their electrogastrogram, urinary glucose and clinical symptoms observed.Results: After treatment, the parameters of electrogastrogram and urinary glucose lowered significantly, and the symptoms relieved. The effect of the treated group was significantly better than that of the control group who were treated with metoclopramide.Conclusion: Dachengqi Decoction is an effective recipe in treating diabetic gastric retention.  
        Keywords：Dachengqi decoction;diabetic gastric retention;electrogastrogram;urinary glucose   
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        Published：2021-08-27
      • Yuan Aping,Liu Chao,Wang Xiuju,Yu Xueduan,Huang Xia
        Vol. 4, Issue 4, Pages: 274(1998) DOI: 10.1007/BF02935476
        Keywords：Neuropathy;Metoclopramide;Verse;aplastic anemia;Gastric Wall   
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        Published：2021-08-27
      • Chen Yanqing,Wu Xiaotong,Chen Wenbin,Shi Wenjie,Li Li
        Vol. 4, Issue 4, Pages: 275-277(1998) DOI: 10.1007/BF02935477
        Abstract：Objective: To observe the effect of combined therapy of acupoint injection and Chinese herbal medicine ion-introduction in treating mammary gland hyperplasia (MGH).Methods: Eighty-six patients of MGH were treated with the combined therapy and compared with a control group treated with other Chinese or western drugs.Results: Therapeutic effect evaluated after 3 courses of treatment showed that the effect of combined therapy was superior to that of the control groups treated by Xiaoyao Pill, Rupixiao tablet, Asparagine tablet and combined therapy of vitamin E+oryzanol+vitamin B6.Conclusion: Combined treatment of acupoint injection and ion-introduction of Chinese herbal medicine is an effective treatment for mammary gland hypertrophy.  
        Keywords：Acupoint Injection;ion-introduction of Chinese herbal medicine;mammary gland hyperplasia   
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        Published：2021-08-27
      • Shen Ziyin,Cai Dingfang,Zhang Lingjuan,Chen Xiaohong,Zhong Liyong
        Vol. 4, Issue 4, Pages: 278-281(1998) DOI: 10.1007/BF02935478
        Abstract：Objective: To observe the acting pattern on the immune system by Kidney tonifying (KT) drugs.Methods: Three composite recipes were used on the 7- and 14-day corticosterone rat model to study the effect of recipes on the different patterns of immuno-modulatory and neuro-endocrinological systems.Results: The immune system of Spleen Invigorating (SI) group was well protected in either 7- or 14-day experiments, with the SI recipe showing no effect on the neuroendocrine system. It suggested that SI recipe might have direct action on immune system. On the other hand, KT group with no effect on neuroendocrine-immune (NEI) system in 7-day experiment, but showed a remarkable protective effect of the whole NEI system in 14-day experiment.Conclusion: The results indicated that KT recipe acts on the neuroendocrine system first, and then influence the immune system. It means that the action took place through down pathway of NEI network.  
        Keywords：Kidney tonifying;Spleen invigorating;corticosterone rat;Youguiyin   
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        Published：2021-08-27
      • Yan Hongbing,Ke Yuannan,Shu Bangming,Ou Zhihong,Zhao Xia,Zhao Guiru
        Vol. 4, Issue 4, Pages: 281(1998) DOI: 10.1007/BF02935479
        Keywords：Coronary Artery;Right Coronary Artery;Left Main Coronary Artery;Coronary Arteriography;Circumflex Coronary Artery   
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        Published：2021-08-27
      • Wang Zhiwei,Gao Shangzhi,Cheng Bangchang,Lin Daoming,Yao Zhen,Tu Zhongfan
        Vol. 4, Issue 4, Pages: 282-285(1998) DOI: 10.1007/BF02935480
        Abstract：Objective: To explore the therapeutic mechanism of the combined use of Radix Salviae Miltiorrhizae, ligustrazine and Radix Sanchi in treating late hemorrhagic shock in rabbit.Methods: Rabbit hemorrhagic shock models were set up according to Wiggers’ method and treated with the combined therapy. Levels of RBC superoxide dismutase (SOD) activity, plasma malondialdehyde (MDA), blood lactate (BL) and magnesium (Mg++) were continuously monitored before shock, 120 minutes after shock, 60 and 120 minutes after reinfusion.Results: (1) Levels of SOD decreased and MDA, BL, Mg++ increased markedly 120 minutes after shock, indicating that there existed cell membrane damage caused by oxygen free radicals in hemorrhagic shock. (2) The combination therapy could alleviate lipid peroxidation injury to tissue, enhance the activity of SOD and lower the concentration of MDA significantly,P < 0.01 or 0.05, as compared with the control group.Conclusion: The combined use of the three drugs could gain the same effect with half dosage as that gained from the whole dosage of one single drug. It could also reduce the negative effect of treatment, such as hypotension and slowing down of heart rate  
        Keywords：Hemorrhagic shock;Radix Salviae Miltiorrhizae;Ligustrazine;Radix Sanchi;combined administration   
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        Published：2021-08-27
      • Li Deyang,Shi Yiting,Chen Yuping,Li Ru,Dai Feng
        Vol. 4, Issue 4, Pages: 285(1998) DOI: 10.1007/BF02935481
        Keywords：Nitric Oxide;Cerebral Infarction;Allopurinol;Ischemic Brain Damage;Ligustrazine   
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        Published：2021-08-27
      • Zhang Dong,Wang Shuyou,Fu Weixing
        Vol. 4, Issue 4, Pages: 286-289(1998) DOI: 10.1007/BF02935482
        Abstract：Objective: To explore the possibility of using cortical infrared thermography (CIT) and temperature in studying the principle of acupuncture and moxibustion.Methods: The changes of the cerebral cortical temperature during electro-acupuncture (EA) measured by CIT in twenty cats were observed. By opening the skull before experiments, the cortex of animals was revealed. The distribution of the cortical temperature of the awakened animals was studied by AGA infrared thermovision, and the thermograms were analysed by computer.Results: (1) The thermograms of the profile of the cortex could be displayed clearly, the temperature was higher in the ante and lower in post-cortex than that in other regions. (2) No tendency of cortical temperature ascending within 30 minutes in cats without EA. (3) After EA, the temperature of cortex generally increased by 0.3 to 1.7 degrees centigrade, and 5 min after EA, the increment of temperature was the highest, 10 min after EA, the temperature increment was higher than before EA, but lower than 5 min after EA. The cortical temperature recovered 10 min after stopping the stimulation. (4) The temperature increment was more obvious in the regions of ant. ectosylvian, ant. supra-Sylvian and ant. Sylvian than that in other regions. No matter where the site of EA was, every group had its own special region of higher temperature increment.Conclusion: The temperature increased in the cortex were mainly in the somatosensory regions. The extent and position of temperature response of cortex after EA could be displayed with CIT directly by picture. The display of the temperature response could be taken as the indication of the nervous activity. CIT could be used to conduct the studies of the acupuncture and the brain.  
        Keywords：infrared thermography;temperature;cerebral cortex;electro-acupuncture;neuro-imaging   
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        Published：2021-08-27
      • Duan Shaobin,Luo Ji’an,Liu Ruihong,Xu Xiping
        Vol. 4, Issue 4, Pages: 290-292(1998) DOI: 10.1007/BF02935483
        Abstract：Objective: Radiographic contrast media can induce renal failure and it may serve as an experimental model of acute renal failure (ARF). The study was aimed to determine the protective effect of Shengmai Injection (SMI) on contrast medium-associated ARF in Sprague-Dawley (SD) rats.Methods: Twenty healthy SD rats of both sex were randomly divided into two groups, Group A (control group) treated with glycerin+0. 9% saline+meglucamine diatrizoate, and group B (preventive group) with glycerin+SMI+meglucamine diatrizoate.Results: In Group B, the levels of blood urea nitrogen, serum creatinine, renal phospholipase A2 (PLA2) and calcium were all significantly lower than those in Group A,P < 0.01. The results indicated the renal injury induced by meglucamine diatrizoate was alleviated by SMI.Conclusion: SMI could prevent renal tissue from contrast media induced nephropathy in SD rats. The effect may partially owe to its preventing intracellular calcium accumulation, inhibiting PLA2 activity and dilating renal vessels.  
        Keywords：nephrotoxicity;contrast media;Shengmai Injection;renal failure;meglucamine diatrizoate   
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        Published：2021-08-27
      • Chen Yongzhen,Lin Bin,Wu Donghong,Zeng Yunxing
        Vol. 4, Issue 4, Pages: 293-295(1998) DOI: 10.1007/BF02935484
        Keywords：Acute Lymphocytic Leukemia;Collagen Synthesis;acute leukemia;Cardiac Fibroblast;Puerarin   
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        Published：2021-08-27
      • Zhao Zhiming,Yang Xiaoying,Zhang Yongzhen,Xiao Zhengyi
        Vol. 4, Issue 4, Pages: 295(1998) DOI: 10.1007/BF02935486
        Keywords：Unstable Angina;Collagen Synthesis;Cardiac Fibroblast;Puerarin;Myocardial Oxygen Consumption   
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      • Song Deming,Su Hai,Wu Meihua,Huang Xueming
        Vol. 4, Issue 4, Pages: 295(1998) DOI: 10.1007/BF02935485
        Keywords：Unstable Angina;Collagen Synthesis;Cardiac Fibroblast;Puerarin;Myocardial Oxygen Consumption   
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      • Chen Weiqiang,Chen Yangshu
        Vol. 4, Issue 4, Pages: 296-297(1998) DOI: 10.1007/BF02935487
        Keywords：Herpes Simplex Virus Type;Acyclovir;Normal Control Group;Competitive Polymerase Chain Reaction;Immune Disturbance   
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      • Zuo Li,Guo Huiyu
        Vol. 4, Issue 4, Pages: 297(1998) DOI: 10.1007/BF02935488
        Keywords：Herpes Simplex Virus Type;Acyclovir;Quantitative Polymerase Chain Reaction;Combine Index;Provement Effect   
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      • Shuqin Mao,Xiaoru Zhang,Jie Bai
        Vol. 4, Issue 4, Pages: 298-300(1998) DOI: 10.1007/BF02935489
        Keywords：Blood Stasis;Total Effective Rate;Alanine Transaminase;Oxymatrine;Whole Blood Viscosity   
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      • Jiqiang Li,Chaoqun Li,Mingde Zeng,Jiangao Fan,Jing Hua,Dekai Qiu,Shudong Xiao,Xiangkui She,Guoqin Li
        Vol. 4, Issue 4, Pages: 300(1998) DOI: 10.1007/BF02935490
        Keywords：chronic hepatitis;Blood Stasis;Alanine Transaminase;Oxymatrine;High Risk Period   
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      • Wenxin Zhu
        Vol. 4, Issue 4, Pages: 301-302(1998) DOI: 10.1007/BF02935491
        Keywords：endometriosis;Western Medicine;Chinese Herbal Medicine;danazol;Blood Stasis   
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      • Vol. 4, Issue 4, Pages: 303-305(1998) DOI: 10.1007/BF02935492
          
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      • Shouyi Wang,Ruihong Dai,Chun Jin
        Vol. 4, Issue 4, Pages: 305(1998) DOI: 10.1007/BF02935493
        Keywords：angina pectoris;Nitroglycerin;Effective Rate;National People;Shanghai Medical   
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      • Vol. 4, Issue 4, Pages: 306-307(1998) DOI: 10.1007/BF02935494
          
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      • Zhufan Xie
        Vol. 4, Issue 4, Pages: 308-310(1998) DOI: 10.1007/BF02935495
        Keywords：Pathogenic Factor;Morbid Condition;Facial Paralysis;Undue Influence;Climatic Phenomenon   
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      • Meilin Xie,Zhenlun Gu,Keji Chen
        Vol. 4, Issue 4, Pages: 311-314(1998) DOI: 10.1007/BF02935496
          
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      • Vol. 4, Issue 4, Pages: 315-317(1998) DOI: 10.1007/BF02935497
          
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