Latest Issue
Vol. 6 ， Issue 2 ， 2000
- Keywords：Traditional Medicine;Western Medicine;Mutual Complement;Tional Medicine;East Asia Market
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Published：2021-08-27 - Keywords：Chinese Medicine;Traditional Medicine;Western Medicine;Ligustrazine;Arsenic Acid
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Published：2021-08-27 -
- Abstract：Objective: To explore the therapeutic effect and the possible working mechanism in using Chinese herbal medicine (CHM) for supplementing Kidney and Qi, and activating blood circulation in treating intrauterine growth retardation of fetus (IUGR). Methods: Fifty-five cases of IUGR were divided into two groups, 30 cases in the CHM group treated with CHM and the 25 in the control group treated with amino acids. The effect of CHM treatment was observed and compared with that of the control group, normal pregnancy group and non-treated IUGR group. Results: Body weight of the newborns in the CHM was markedly higher than that in the control group. Not only the maternal fundal height (FH) and the abdominal circumference (AC), but also the fetal growth parameters, including biparietal diameter, head circumference (HC), and femur length (FL) in the CHM group increased much faster than those in the control group. After CHM treatment, the maternal serum levels of estriol (E3) and human placental lactogen (hPL) approached to those in the normal pregnancy group, but the control group, in comparison with the normal pregnancy group, was significantly different. The umbilical venous plasma concentration of essential amino acids in both treated groups improved, but the improvement in the CHM group was more significant than that in the control group. No apparent adverse effect of CHM was observed in either mother or fetus. Conclusion: CHM for supplementing Kidney and Qi and activating blood circulation was more effective in improving placental function and enhancing amino acid transportation than amino acid.Keywords：Intrauterine Growth Retardation;Chinese herbal medicine for supplementing Kidney and Qi and activating blood circulation;placental function;amino acid
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Published：2021-08-27 - Abstract：Objective: To explore the therapeutic mechanism of Bushen Yugong Granule (BSYGG, a Chinese medicinal preparation) in treating infertility due to uterine dysgenesia.Methods: (1) Clinical study: Serum level of sex hormone and endometrial contents of estradial receptor (ER) and progesterone receptor (PR) in follicle period of 60 patients (the tested group) were measured and compared before and after treatment, and also compared with those of 70 normal women (the control group). (2) Experimental study: Rats were divided into the control group and 3 tested groups fed with different doses of BSYGG. Pathologic examination of pituitary, ovary and uterus of rats after BSYGG treatment were performed, and serum levels of ER, PR measured. Also, an estrogen activity experiment was conducted in some young oophorectomized rats.Results: (1) Clinical study showed the difference of serum sex hormone levels between the tested and control group was insignificant. The percentage of patients in the tested groups with endometrial ER content over ++ was lower than that in the control group (46.9 % vs 72.4 %) significantly (P < 0.05), after treatment, it rose to 65.4 %, and the change was significant, P<0.05. (2) Experimental study showed that the number of follicle, weight of uterus and serum E2 level increased significantly after BSYGG treatment. The endometrial content of ER in the control group was 29.25±17.03%, while in the tested groups, it was 67.75 ± 24.56% to 83.00 ± 9.87% after treatment, the difference between the two groups was significant (P<0.005).Conclusion: BSYGG has an estrogen-like activity, it could increase the endometrial content of ER, enhance the effect of estrogen on uterus and promote the development of uterus, so as to elevate fertilization rate.Keywords：Bushen Yugong Granule;uterine dysgenesia;Infertility;sex hormone receptor
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Published：2021-08-27 - Keywords：Nitric Oxide;Infertility;Western Medicine;Chinese Herbal Medicine;Coronary Heart Disease Patient
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Published：2021-08-27 - Abstract：Objective: To explore the therapeutic effect of shengmai injection (SMI) on respiratory function in chronic obstructive pulmonary disease (COPD).Methods: Twenty patients with COPD were continuously treated with SMI by intravenous drip for 14 days and their lung vital capacity (VC), forced vital capacity (FVC), forced vital capacity of the first second (FEV1), FEV1/FVC, maximum voluntary ventilation (MVV), maximum inspiratory pressure (MIP),load respiratory time (LT), 6 minute walk distance (6 MWD), arterial blood gas analysis, and Borg dyspnea scale were examined respectively before and after treatment and compared before and after treatment or with the control group.Results: After treatment all parameters in the treated group were significantly better than those in the control group or than those before treatment (P<0.05) with the exception of FVC and FEV1/FVC.Conclusion: SMI could improve respiratory function in COPD. So it is an effective rehabilitative injection in treating COPD.Keywords：Shengmai Injection;Chronic Obstructive Pulmonary Disease;respiratory function
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Published：2021-08-27 - Abstract：Objective: To study the mechanism of Sini Decoction (SND) in prevention and treatment of post-percutaneous transluminal coronary angioplasty (PTCA) ischemia-reperfusion injury with different Syndrome typing of TCM.Methods: Forty patients who received PTCA were randomly divided equally into the SND group and the control group, there were 10 of Excess Syndrome (ES) and 10 of Deficiency Syndrome (DS)in each group. 25 ml SND was given daily to the SND group from 3 days before operation to the third day after operation. The blood Superoxide dismutase (SOD) activity, malondialdehyde (MDA) and nitric oxide (NO) content of patients were determined before PTCA, and 1 hr, 12 hrs, 24 hrs, 48 hrs and 72 hrs after PTCA.Results: Before PTCA, the cases with DS were characterized by low SOD activity and high MDA content, as compared with the patients with ES, P<0.05. SND could relieve the post-PTCA deprivation of SOD activity and NO content and the elevation of MDA level in both ES and DS patients, the amplitude of elevation of SOD activity in DS patients was higher than that in ES patients (P<0.05).Conclusion: SND has antagonizing effect on post-PTCA ischemia-reperfusion injury, which is more effective in treating patients with DS.Keywords：Sini Decoction;percutaneous transluminal coronary angioplasty;Syndrome typing;ischemiareperfusion injury
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Published：2021-08-27 - Abstract：Objective: To determine the influence of Sini Decoction (SND) on quality of life(QOL) of patients after percutaneous transluminal coronary angioplasty (PTCA).Methods: Randomized case-control clinical trial was conducted to evaluate QOL of 40 post-PTCA patients before and after SND treatment by scoring.Results: The scores in physical symptoms, sense of well-being, degree of depression, index of satisfaction of life and work capacity of the patients after PTCA were improved significantly as compared with before PTCA,P< 0.01. Scores of patients who received SND treatment were higher than those untreated with SND in the first three criteria, P<0.05, particularly in relieving palpitation and dyspnea.Conclusion: SND is helpful in improving QOL of patients after PTCA.Keywords：quality of life;Sini Decoction;percutaneous transluminal coronary angioplasty
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Published：2021-08-27 - Keywords：Analgesic Effect;pain threshold;Coronary Angioplasty;Pain Model;Positive Control Group
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Published：2021-08-27 - Abstract：Objective: To explore the mechanism of Buyang Huanwu Decoction (BHD) in treating early cerebral infarction.Methods: Seventy cases with early cerebral infarction were randomly divided into two groups. Chinese medicine group (CMG, n = 35) was treated with BHD; western medicine group (WMG, n = 35) was treated with hydroxyethyl starch injection and enteric coated aspirin tablets. The levels of endothelin (ET) and calcitonin gene related peptide (CGRP) in plasma before and after treatment and the results of clinical treatment were observed. Also healthy subjects were used as the normal control.Results: The levels of ET before treatment in the two treated groups were significantly higher than that of the healthy subjects (P<0. 001), and the levels of CGRP were significantly lower (P < 0.001). After treatment the metabolic imbalance of ET and CGRP improved significantly in the two treated groups (P<0. 001), but the ET and CGRP in CMG improved more obviously than those in WMG (P<0.01, P<0.05). The markedly effective and curative rate of CMG was higher than that of WMG (68. 6 % vs 31.4 %; ϰ2 = 9. 65, P < 0. 01).Conclusion: BHD could improve the metabolic imbalance of ET and CGRP in patients with early cerebral infarction and on the virtue of this mechanism it could be used to treat cerebral infarction.Keywords：Buyang Huanwu Decoction;Cerebral Infarction;endothelin;calcitonin gene related peptide;metabolic imbalance
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Published：2021-08-27 - Keywords：Cerebral Infarction;Effective Rate;cellular immunity;Total Effective Rate;Ulcer Recurrence
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Published：2021-08-27 - Abstract：Objective: To study immune function of children viral myocarditis and to evaluate the clinical effect of Shuanghuanglian Powder (SHLP) by injection.Methods: The 62 patients of viral myocarditis were divided into two groups randomly, the SHLP group (n = 32) treated with conventional therapy plus SHLP and the conventional treatment group (n = 30) with conventional therapy alone. Their serum antibody of Coxsackie virus group B (COXB-IgM), T-lymphocyte subsets including CD3 +, CD4 +, CD8 + and CD4 +/CD8 + were determined with ELISA and indirect immunofluorescent assay.Results: COXB-IgM was positive in 39 of the 62 patients, which was significantly different with those of normal controls (P< 0.001). Patients’ serum level of CD4 + cells and CD4 +/CD8 + ratio decreased while CD8 + increased. After treatment, the recovery of symptoms, signs and immune function in patients of the SHLP group were significantly better than those in patients treated with conventional treatment alone (P<0.01).Conclusion: Immunoregulatory disturbance is involved in children with viral myocarditis and SHLP is an effective drug in the treatment of children viral myocarditis.Keywords：Shuanghuanglian Powder;infantile viral myocarditis;T-lymphocyte subset;Coxsackievirus group B antibody
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Published：2021-08-27 - Keywords：Cervical Spine;Myocarditis;Cervical Vertebra;Viral Myocarditis;Coxsackie Virus
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Published：2021-08-27 - Abstract：Objective: To observe the clinical therapeutic effect of Shenmai Injection (SMI) in treating patients of congestive heart failure.Methods: Effect of 16 cases treated with either SMI or potassium magnesium aspartate was observed by randomized crossover method and compared.Results: By using SMI for 2 weeks, the patients’ left ventricular ejective fraction (LVEF) was increased from 29.5 ± 9.0 to 36.6 ± 10.2 (P < 0.05), the heart function of 68.75% patients was improved, no side effect or toxicity was observed. Potassium magnesium aspartate improved the heart function in 37. 50% patients only but showed no effect on LVEF.Conclusion: SMI is an effective and safe drug in treating patients with congestive heart failure.Keywords：congestive heart failure;Shenmai injection;heart function
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Published：2021-08-27 - Keywords：Rheumatic Heart Disease;creatine phosphokinase;Chronic Congestive Heart Failure;Serum Creatine Phosphokinase;tetramethylpyrazine
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Published：2021-08-27 - Abstract：Objective: To investigate the clinical efficacy of Serenity, an Australia Government listed Chinese herbal patent medicine, in the treatment of long-term insomnia.Methods: Adopting randomized double blind placebo controlled cross-over method, 19 volunteers participated were enrolled in this study for a period of 12 weeks. Each phase of the trial lasted for six weeks. No washout period was implemented. Assessment was based on the Vital Sign Test, Sleep Parameter Questionnaire, Leeds Sleep Evaluation Questionnaire and the Side Effects Questionnaire.Results: Serenity improved significantly the Overall Sleep Evaluation in the treated group, in comparing with that in the control group, P<0.01. Therapeutic effect reached the peak at the end of the fourth week of the treatment period.Conclusion: Serenity, a Chinese herbal patent medicine, is effective for the clinical management of long-term insomnia.Keywords：insomnia;sleep disorder;Chinese Herbal Medicine;Serenity
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Published：2021-08-27 - Abstract：Objective: To explore the effect of Tiangui Recipe (TGR) on obesity and reproductive function in androgen-sterilized rats (ASR).Methods: ASR model was established by subcutaneous injection of testosterone propionate to SD female rats at the age of 9 days. Change of serum leptin, follicular stimulating hormone (FSH) and luteinizing hormone (LH) in model rats aged 115 days before and after feeding them with TGR was measured by radioimmunoassay (RIA). Meanwhile, criteria of energy state, including diurnal food intake, retroperitoneal fat depot weight and body weight, were measured and evaluated.Results: ASR had the characteristics of high metabolic rate, energy imbalance and obesity. Serum level of leptin increased and FSH, LH decreased significantly (P<0.01) in model rats as compared with the normal rats. Significant positive correlation between leptin level and body weight (r=0.8977, P<0.001) was observed, and negative correlation was seen between FSH, LH and leptin (r = -0.7517, P<0.001; r= -0.8444, P<0.001, respectively). The endocrine changes of ASR all returned to normal range after the TGR treatment.Conclusion: Obesity and concerned hypogonadotrophic hypogonadal anovulation were expressed in ASR. TGR may play an important role in reducing weight and inducing ovulation.Keywords：Tiangui Recipe;androgen-sterilized rat;leptin;Pituitary Gonadotropin
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Published：2021-08-27 - Keywords：Eating Disorder;Chinese Herbal Medicine;Anovulation;Activate Blood Circulation;Ovary Adrenal Gland
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Published：2021-08-27 - Abstract：Objective: To study the effect of Astragalus (As) on left ventricular collagen remodeling after myocardial infarction in rats.Methods: Myocardial collagen (MC) and ratio of myocardial collagen type I and M in rat models of myocardial infarction treated with Astragalus injection were determined and compared with those in sham operated rats and in captopril(CAP) treated rats.Results: MC and ratio of MC I /IE of non-in-farcted region in the myocardial infarction rats was higher than that in the sham group. Both AS and CAP could restrain the ascending trend of these parameters.Conclusion: Astragalus is effective in lowering the elevation of MC after infarction and changing the MC I /H ratio, therefore, is beneficial to improve the systolic and diastolic function of left ventricle after acute myocardial infarction.Keywords：Astragalus;acute myocardial infarction;myocardial collagen;Captopril;ventricular function
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Published：2021-08-27 - Keywords：Losartan;Homovanillic Acid;Ascorbic Acid Level;Experimental Myocardial Infarction;Oral Liquid
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Published：2021-08-27 - Abstract：Objective: To observe the protective effect of theo-polyphenols (TP) on hepatic histology of hyperlipidemia model in quails.Methods: Model of hyperlipidemia in quails was established. The 75 male quails were divided randomly into 5 groups, 15 in each group. The non-hyperlipidemia group (normal control group) was fed with ordinary forage. The hyperlipidemia group (hyperlipidemia control group) was fed with high lipid forage. The three TP groups were fed with high lipid forage together with a low (25 mg/kg), middle (50 mg/ kg) and high (100 mg/kg) dose of TP respectively. The total experimental period was 6 weeks for all the quails.Results: TP could prevent the increase of serum total cholesterol (TC), triglycerides (TG), low-density lipoprotein cholesterol (LDL-C) and liver index (LI) caused by high lipid food, thus showing protective dosedependant effect on hepatic histology in hyperlipidemia.Conclusion: TP has the effect of regulating serum lipids in preventing and treating fatty liver.Keywords：theo-polyphenols;hyperlipidemia;Fatty Liver;histology;quail
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Published：2021-08-27 - Keywords：Catechin;Fatty Liver;Lipoprotein Lipase;Activate Blood Circulation;Micellar Solubility
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Published：2021-08-27 - Abstract：To terminate early stage pregnancy by combination of Mifepristone and Misoprostol is superior in high success rate, convenient use and less misery, but with the main badness of inducing irregular vaginal bleeding harmful to psychosomatic condition of puerpera. From March 1993 to December 1995, Yaoliuan Capsule (YLAC) was used by the authors to treat the drug-induced post-abortion vaginal bleeding and good effect was achieved. The study was introduced as follows.Keywords：Misoprostol;Vaginal Bleeding;Mifepristone;Blood Stasis;Ball Discharge
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Published：2021-08-27 - Abstract：The diagnostic method of early tubal pregnancy has been improved progressively in recent years, and more attention is paid to conservative therapy of the disease. Combination therapy of Chinese herbal medicine (CHM) for activating blood circulation to remove blood stasis and methotrexate (MTX) administration by tubal intubation under uteroscope has been used since 1995 in treating 12 patients of tubal pregnancy and satisfactory effect obtained. The report is as follows.Keywords：Chinese Herbal Medicine;Tubal pregnancy;Activate Blood Circulation;Promote Blood Circulation;Basal Body Temperature
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Published：2021-08-27 - Abstract：From Feb. 1994 to Oct. 1997, 67 cases with tuberculous exudative pleurisy were treated with chemotherapy and fluid aspiration by thoracic puncture, combined with compound Salviae miltiorrhizae injection (CSMI) through intravenous and thoracic cavity injection, and a good clinical effect was obtained.Keywords：Pleural Fluid;Pyrazinamide;Pleurisy;Fluid Aspiration;Remove Blood Stasis
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Published：2021-08-27 - Abstract：From Dec. 1955 to June 1997, 121 inpatients of labour angina pectoris (LAP) were treated with puerarine, ligustrazin and mailuoning respectively by the authors, the effect of treatment was observed and analysed as follows.Keywords：K562 Cell;Chronic Myelogenous Leukemia;Total Effective Rate;Peking Union Medical College;Ligustrazine
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Published：2021-08-27 - Keywords：K562 Cell;Chronic Myelogenous Leukemia;Total Effective Rate;Myocardial Oxygen Consumption;Peking Union Medical College
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Published：2021-08-27 - Abstract：Fifty patients of Candida albicans vaginitis were treated with Cortex Sophorae from Feb. 1992 to Feb. 1996 by the authors and good effect was obtained. The summary is reported as follows.Keywords：Candida Albicans;Total Effective Rate;Vaginitis;Ming Dynasty;Vaginal Discharge
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Published：2021-08-27 - Keywords：Flavonoid;Cell Mediate Immunity;Total Effective Rate;Vaginitis;Ming Dynasty
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Published：2021-08-27 -
- Keywords：Glial Fibrillary Acidic Protein;Alzheimer Disease;Brain Cortex;Cala;Common Cold
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Published：2021-08-27 -
- Keywords：Nephrotic Syndrome;Corticosterone;Urinary Protein;Corti;Chinese Herbal Medicine
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Published：2021-08-27 - Keywords：Morbid Condition;Febrile Disease;Dull Pain;Tongue Coating;Rapid Pulse
- 620
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Published：2021-08-27 - Keywords：Menthol;Chronic Renal Failure Patient;Licorice Root;Irregular Menstruation;Storage Store
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Published：2021-08-27 - Keywords：Captopril;chronic renal failure;Chronic Renal Failure Patient;Short Breath;Gastric Atonia
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Published：2021-08-27 - Abstract：Yupingfeng Powder (YPFP, ), a recipe which consists of Radix Astragalus, Rhizoma Atractylodes Alba and Radix Sileris is originally from the book “Experiences of ZHU Danxi” (written by ZHU Danxi, a famous doctor in the Yuan Dynasty). FZ Kong, YH Shen, et al found that YPFP had action on anti-bacterial adhesion. (1,2) It was used in clinical practice to prevent diseases of respiratory tract, such as Wind-Cold, respiratory infection, allergic rhinitis, bronchial asthma. It was recently found that YPFP could affect extensively the immune system, and the related studies were summarized in this article as follows.Keywords：Allergic Rhinitis;Chronic Bronchitis;Yuan Dynasty;Plaque Formation Cell;H202 Release
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Published：2021-08-27
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