Relationship between various Chinese medicine types and T-cell subsets in patients with ulcerative colitis

Ting-min Chang; Xiu-min Li; Xi-de Zhao

doi:10.1007/s11655-009-0220-y

Your Location：

Home >

Browse articles >

Relationship between various Chinese medicine types and T-cell subsets in patients with ulcerative colitis

OriginalPaper | Updated：2021-08-27

- Relationship between various Chinese medicine types and T-cell subsets in patients with ulcerative colitis
- Relationship between various Chinese medicine types and T-cell subsets in patients with ulcerative colitis
- 中国结合医学杂志（英文版） 2009年15卷第3期页码：220-223
- Affiliations：
  
  1. Department of Internal Digestive Medicine, First Affiliated Hospital of Xinxiang Medical College,Henan,China
  2. Wuhan Union Hospital, Tongji Medical College of Huazhong University of Science and Technology,Wuhan,China
  3. Department of Integrative Chinese and Western Medicine, First Affiliated Hospital of Xinxiang Medical College,Henan,China
- Author bio：
- Funds：
- DOI：10.1007/s11655-009-0220-y
  中图分类号：
- 纸质出版日期：2009，
  
  网络出版日期：2009-7-2，
Scan for full text
Chang, Tm., Li, Xm. & Zhao, Xd. Relationship between various Chinese medicine types and T-cell subsets in patients with ulcerative colitis., Chin. J. Integr. Med. 15, 220–223 (2009). https://doi.org/10.1007/s11655-009-0220-y

Ting-min Chang, Xiu-min Li, Xi-de Zhao. Relationship between various Chinese medicine types and T-cell subsets in patients with ulcerative colitis[J]. Chinese Journal of Integrative Medicine, 2009,15(3):220-223.
Chang, Tm., Li, Xm. & Zhao, Xd. Relationship between various Chinese medicine types and T-cell subsets in patients with ulcerative colitis., Chin. J. Integr. Med. 15, 220–223 (2009). https://doi.org/10.1007/s11655-009-0220-y DOI：

Ting-min Chang, Xiu-min Li, Xi-de Zhao. Relationship between various Chinese medicine types and T-cell subsets in patients with ulcerative colitis[J]. Chinese Journal of Integrative Medicine, 2009,15(3):220-223. DOI： 10.1007/s11655-009-0220-y.

摘要

To investigate the relationship between various Chinese medicine (CM) types and T-cell subsets (CD4+ and CD8+) in the colonic mucous membranes of patients with ulcerative colitis (UC). Fifty UC patients were enrolled

after differentiation into four types by CM syndromes

i.e.

the internal heat-damp accumulation type (IHDA)

the qi-stagnancy with blood stasis type (QSBS)

the Pi (脾)-Shen (肾) yang-deficiency type (PSYD) and the yin-blood deficiency type (YBD). From every patient

3–5 pieces of intestinal mucous membrane tissues were taken through colonoscopy to determine the levels of the T-cell subsets (CD4+ and CD8+) using immunohistochemical method. The results were compared with those in the normal control. The level of CD8+increased and the ratio of CD4+/CD8+decreased mainly in colonic mucous membranous tissues in UC patients. The level of CD4+decreased significantly in IHDA types (P<0.01)

but decreased only slightly in the PSYD

QSBS and YBD types. CD8+increased significantly in the IHDA types (P<0.01)

but only slightly in the other three types. The IHDA types of UC are closely related with T-cell subsets. The difference of T-cell subsets in various IHDA types of UC patients has provided a theoretical basis for syndrome differentiation in the CM typing of UC.

Abstract

after differentiation into four types by CM syndromes

i.e.

the internal heat-damp accumulation type (IHDA)

the qi-stagnancy with blood stasis type (QSBS)

the Pi (脾)-Shen (肾) yang-deficiency type (PSYD) and the yin-blood deficiency type (YBD). From every patient

but decreased only slightly in the PSYD

QSBS and YBD types. CD8+increased significantly in the IHDA types (P<0.01)

关键词

Ulcerative ColitisChinese medicine typingT cell subset

Keywords

Ulcerative ColitisChinese medicine typingT cell subset

references

Lin Y, Wang XY, Tian DL, Cui W, Li XL. Comparison of warm and purgative remedy and warm and restraining diarrhea remedy on the T-cell subsets of ulcerative colitis in fresh peripheral blood lymphocytes. Chin J Integr Tradit West Med Dig (Chin) 2006;14:78–81.

Chen BT. Effect of matrine injection on the cellular immunity in peripheral blood of patients with ulcerative colitis. Chin J Integr Tradit West Med Dig (Chin) 2005;13:313–315.

Li GZ, Wen FH, Li TJ, Zhao XL. Detection of T-lymphocyte and ulcerative colitis. Clin Focus (Chin) 2004;19(12): 711

Li GH, Liao WD, Li BL, Li P, Zhou XJ, Wang J. Levels of complement, T cell subsets and immunoglobulin of peripheral blood in patients with ulcerative colitis. Acta Academiae Med Jiangxi (Chin) 2006;46:63–64, 67.

Yan J, Ouyan Q. Imbalance of the ratio of inflammatory bowel disease and T cell subsets. Foreign Med Sci (Dig Dis, Chin)1999;19: 83–87.

Gao YF, Zhu ZM, Li X. Discussion on the relationship between the syndrome of traditional Chinese medicine and chemical and biological material of chronic ulcerative colitis. J Xi’an Med Univ (Chin) 1996,17:356–358.

The Fourth Symposium by Professional Committee of digestive diseases, Chinese Asscociation of Integrative Chinese and Western Medicine. Standard of integrative medical diagnosis, syndrome differentiation and efficacy evaluation for chronic non-specific ulcerative Colitis (draft). Chin J Integr Tradit West Med (Chin) 1994;14: 239–240

Zheng CQ, Hu GZ. Guideline of new understanding on CD4+ T-lymphocyte subsets and inflammatory bowel disease study. World Chin J Dig (Chin) 2004;12:505–511.

Macdonald TT, Monteleone G. Immunity, inflammation, and allergy in the gut. Science 2005; 307: 1920–1925.

Rook GA, Brunet LR. Microbes, immunoregulation, and the gut. Gut 2005; 54: 317–320.

Powrie F. Immune regulation in the intestine: a balancing act between effector and regulatory T cell responses. Ann NY Acad Sci 2004;1029:132–141.

Duchmann R, Kaiser I, Hermann E, Mayet W, Ewe K, Meyer zum Büschenfelde KH. Tolerance exists towards resident intestinal flora but is broken in active inflammatory bowel disease (IBD). Clin Exp Immunol 1995; 102: 448–455

Allez M, Mayer L. Regulatory T cells: peace keepers in the gut. Inflamm Bowel Dis 2004;10:666–676.

Jiang XL, Cui HW. Ulcerative colitis. Beijing: China Medico-Pharmaceutical Sciences and Technology Publishing House; 2005:42.

Zhang WK, Chen KJ, Wu XZ. Integrated traditional and Western medicine. Beijing: China Press of Traditional Chinese Medicine; 2000:673–674.

Ye RG, Lu ZY. Internal Medicine. 6th ed. Beijing: People’s Medical Publishing House; 2004:408.

FULL TEXT LINK

More>

浏览量

349

Downloads

CSCD

文章被引用时，请邮件提醒。

Submit

工具集

关联资源

Effects of Modified Sanhuang Decoction (加味三黄汤) enema on serum tumor necrosis factor-α and colonic mucosa interleukin-1β, interleukin-6 levels in ulcerative colitis rats

Role of β2-adrenoceptor-β-arrestin2-nuclear factor-κB signal transduction pathway and intervention effects of oxymatrine in ulcerative colitis

Review on efficacy and health services research studies of complementary and alternative medicine in inflammatory bowel disease

Protective effect of Jiechangning decoction in treating experimental ulcerative colitis in guinea pigs