Combined therapy with Chinese medicine and percutaneous transradial coronary intervention for a centenarian patient with acute myocardial infarction

Lei Wang; Min-zhou Zhang; Guang Yang

doi:10.1007/s11655-009-0233-6

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Combined therapy with Chinese medicine and percutaneous transradial coronary intervention for a centenarian patient with acute myocardial infarction

OriginalPaper | Updated：2021-08-27

- Combined therapy with Chinese medicine and percutaneous transradial coronary intervention for a centenarian patient with acute myocardial infarction
- Combined therapy with Chinese medicine and percutaneous transradial coronary intervention for a centenarian patient with acute myocardial infarction
- 中国结合医学杂志（英文版） 2009年15卷第3期页码：233-235
- Affiliations：
  
  Heart Center, Guangdong Provincial Hospital of Chinese Medicine,Guangzhou,China
- Author bio：
- Funds：
  
  Supported by Scientific Research Project of Public Welfare Industry, State Administration of Traditional Chinese Medicine of P.R. China (No. 200707004)
- DOI：10.1007/s11655-009-0233-6
  中图分类号：
- 纸质出版日期：2009，
  
  网络出版日期：2009-7-2，
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Wang, L., Zhang, Mz. & Yang, G. Combined therapy with Chinese medicine and percutaneous transradial coronary intervention for a centenarian patient with acute myocardial infarction., Chin. J. Integr. Med. 15, 233–235 (2009). https://doi.org/10.1007/s11655-009-0233-6

Lei Wang, Min-zhou Zhang, Guang Yang. Combined therapy with Chinese medicine and percutaneous transradial coronary intervention for a centenarian patient with acute myocardial infarction[J]. Chinese Journal of Integrative Medicine, 2009,15(3):233-235.
Wang, L., Zhang, Mz. & Yang, G. Combined therapy with Chinese medicine and percutaneous transradial coronary intervention for a centenarian patient with acute myocardial infarction., Chin. J. Integr. Med. 15, 233–235 (2009). https://doi.org/10.1007/s11655-009-0233-6 DOI：

Lei Wang, Min-zhou Zhang, Guang Yang. Combined therapy with Chinese medicine and percutaneous transradial coronary intervention for a centenarian patient with acute myocardial infarction[J]. Chinese Journal of Integrative Medicine, 2009,15(3):233-235. DOI： 10.1007/s11655-009-0233-6.

摘要

There are not enough clinical data about centenarians with acute myocardial infarction (AMI) undergoing percutaneous coronary intervention (PCI). A 104-year-old woman exhibited sharp chest pain and severe dyspnea. In routine examinations

her electrocardiogram showed 1–3 mm ST-segment elevation from V1 to V4 leads

the cardiac enzymes were also elevated: creatine kinase (CK)-MB was 45.7 U/L

and cardiac specific troponin I was 40 μg/L. A two-dimensional echocardiography showed anteroseptal akinesia with severely depressed left ventricular function

38% ejection fraction. She primarily refused to receive percutaneous coronary intervention (PCI) considering her old age

and she was given a dual anti-platelet medications (low molecular heparin and frusemide). Three days later

due to continuously deteriorating angina pectoris and dyspnea

she was treated with PCI. A diagnostic percutaneous transradial coronary angiography revealed 95% stenosis in the proximal left anterior descending artery (LAD) with 90% stenosis at the origin of diagonal one. A percutaneous coronary intervention for the LAD lesion was successfully performed

and the final angiogram showed a good coronary flow without residual stenosis. The dual anti-platelet medications had to be ceased due to the upper gastrointestinal bleeding after one week and Tongguan Capsule (通冠胶囊

Chinese medicine composed with Radix Astragali

Radix Salviae Miltiorrhiae

etc.) was administered continuously. The six-month follow-up displayed a high level quality of life for the centenarian woman with the absence of angina pectoris and dyspnea. The case reinforces the importance of PCI for very elderly patients with AMI even centenarian people and reveals the possibility that Tongguan Capsule can be used to replace dual anti-platelet medication with the reduction of bleeding complications.

Abstract

her electrocardiogram showed 1–3 mm ST-segment elevation from V1 to V4 leads

the cardiac enzymes were also elevated: creatine kinase (CK)-MB was 45.7 U/L

and cardiac specific troponin I was 40 μg/L. A two-dimensional echocardiography showed anteroseptal akinesia with severely depressed left ventricular function

38% ejection fraction. She primarily refused to receive percutaneous coronary intervention (PCI) considering her old age

and she was given a dual anti-platelet medications (low molecular heparin and frusemide). Three days later

due to continuously deteriorating angina pectoris and dyspnea

Chinese medicine composed with Radix Astragali

Radix Salviae Miltiorrhiae

关键词

acute myocardial infarctionPercutaneous Coronary InterventionChinese Medicinecentenarian

Keywords

acute myocardial infarctionPercutaneous Coronary InterventionChinese Medicinecentenarian

references

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Valente S, Lazzeri C, Salvadori C, Chiostri M, Giglioli C, Poli S, et al. Effectiveness and safety of routine primary angioplasty in patients aged > or =85 years with acute myocardial infarction. Circ J 2008;72:67–70.

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Zhang XW, Zhang MZ. Effect of Tongguan Capsule on coagulant and fibrinolysis system in patients with coronary heart disease after percutaneous coronary intervention. Chin J Integr Tradit West Med (Chin) 2004;24:1065–1068.

Cao AQ, Tian WJ, Li Song. The influence of Tongguan Capsule on contents of GMP-140 and vWF of patients with coronary heart disease after PCI. Chin J Integr Med Cardio-/Cerebrovas Dis 2004;2:685–686.

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